IC87201

Product Name: IC87201
CAS No.: 866927-10-8
Chemical Name: IC87201
Synonyms: IC87201;IC-87201 (IC87201;IC87201 >=98% (HPLC);IC87201, 10 mM in DMSO;2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol;Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-;2-{[(1H-1,2,3-benzotriazol-6-yl)amino]methyl}-4,6-dichlorophenol;2-(((1H-Benzo[d][1,2,3]triazol-6-yl)amino)methyl)-4,6-dichlorophenol;IC 87201,IC87201,IC-87201,inhibit,iGluR,Inhibitor,Ionotropic glutamate receptors
CBNumber: CB53146614
Molecular Formula: C13H10Cl2N4O
Formula Weight: 309.15
MOL File: 866927-10-8.mol

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IC87201 Property

storage temp.: Store at -20°C
solubility: DMF:30.0(Max Conc. mg/mL);97.04(Max Conc. mM)
DMSO:29.0(Max Conc. mg/mL);93.81(Max Conc. mM)
DMSO:PBS (pH 7.2) (1:3):0.25(Max Conc. mg/mL);0.81(Max Conc. mM)
Ethanol:1.0(Max Conc. mg/mL);3.23(Max Conc. mM)
form: A solid
color: Pink to red
InChI: InChI=1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19)
InChIKey: QEHVTUCLCBXQIC-UHFFFAOYSA-N
SMILES: C1(O)=C(Cl)C=C(Cl)C=C1CNC1C=C2NN=NC2=CC=1

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Safety

WGK Germany: WGK 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Eye Irrit. 2
Skin Irrit. 2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML1910
Product name: IC87201
Purity: ≥98% (HPLC)
Packaging: 5MG
Price: $78.7
Updated: 2026/03/19

Sigma-Aldrich

Product number: SML1910
Product name: IC87201
Purity: ≥98% (HPLC)
Packaging: 25MG
Price: $413
Updated: 2023/01/07

Tocris

Product number: 6226
Product name: IC87201
Purity: ≥99%(HPLC)
Packaging: 50
Price: $557
Updated: 2021/12/16

Tocris

Product number: 6226
Product name: IC87201
Purity: ≥99%(HPLC)
Packaging: 10
Price: $133
Updated: 2021/12/16

ChemScene

Product number: CS-5875
Product name: IC87201
Purity: 97.29%
Packaging: 25mg
Price: $280
Updated: 2021/12/16

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IC87201 Chemical Properties,Usage,Production

Uses

IC 87201 (cas# 866927-10-8) is a useful research chemical.IC 87201 is a small molecule inhibitor. It inhibited the in vitro binding of nNOS with PSD95, without inhibiting nNOS catalytic activity.

Biological Activity

IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction th at blocks NMDA-induced 3μ ,5μ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memory, spatial memory, and motor function in rats.

in vivo

IC87201 (1, 4 and 10 mg/kg, i.p.) does not produce impairment in either spatial working memory or source memory^[2]. IC87201 (1 mg/kg) is effective in treating NMDA-induced thermal hyperalgesia in mice, with a corresponding peak plasma level of 55 ng/mL (or 0.2 μM)^[3].

IC 50

NMDA Receptor

IC87201 Preparation Products And Raw materials

Raw materials

Preparation Products

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IC87201 Suppliers

China 52 United Kingdom 1 United States 8 Global 61

Shanghai Luofa Biochemical Technology Co., Ltd.

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866927-10-8, IC87201Related Search:

IC87201

2-[(1H-Benzotriazol-6-ylamino)methyl]-4,6-dichlorophenol

IC-87201 (IC87201

Phenol, 2-[(1H-benzotriazol-6-ylamino)methyl]-4,6-dichloro-

IC87201 >=98% (HPLC)

2-(((1H-Benzo[d][1,2,3]triazol-6-yl)amino)methyl)-4,6-dichlorophenol

IC 87201,IC87201,IC-87201,inhibit,iGluR,Inhibitor,Ionotropic glutamate receptors

2-{[(1H-1,2,3-benzotriazol-6-yl)amino]methyl}-4,6-dichlorophenol

IC87201, 10 mM in DMSO

866927-10-8

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