ChemicalBook > CAS DataBase List > Anavex 2-73

Anavex 2-73

Product Name
Anavex 2-73
CAS No.
195615-84-0
Chemical Name
Anavex 2-73
Synonyms
CS-2759;Anavex 2-73;AVex-73 HCl;Blarcamesine;Anavex2-73 HCl;AVex-73 hydrochL;AE-37 HYDROCHLORIDE;AN2/AVEX-73 HCL SALT;AVex-73 hydrochloride;Anavex 2-73(ANAVEX2-73)
CBNumber
CB53151652
Molecular Formula
C19H24ClNO
Formula Weight
317.86
MOL File
195615-84-0.mol
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Anavex 2-73 Property

Melting point:
165 - 168°C
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
White to Off-White
InChI
InChI=1S/C19H23NO.ClH/c1-20(2)15-18-13-14-21-19(18,16-9-5-3-6-10-16)17-11-7-4-8-12-17;/h3-12,18H,13-15H2,1-2H3;1H
InChIKey
FEQOLYDPQKHFTD-UHFFFAOYSA-N
SMILES
C(C1CCOC1(C1C=CC=CC=1)C1C=CC=CC=1)N(C)C.Cl
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P273Avoid release to the environment.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC
Product number
A637195
Product name
Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamineHydrochloride(>75%)
Packaging
25mg
Price
$125
Updated
2021/12/16
Usbiological
Product number
254635
Product name
ANAVEX 2-73
Packaging
10mg
Price
$446
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
50mg
Price
$660
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
100mg
Price
$972
Updated
2021/12/16
ChemScene
Product number
CS-7904
Product name
Blarcamesine(hydrochloride)
Purity
99.85%
Packaging
5mg
Price
$132
Updated
2021/12/16
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Anavex 2-73 Chemical Properties,Usage,Production

Uses

Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine Hydrochloride is a useful therapeutic in the treatment of humans suffering from insomnia, anxiety, or agitation.Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine Hydrochloride is also used in pharmacological studies such as the anti-amnesic and neuroprotective potentials of mixed muscarinic receptor/σ1 ligand ANAVEX2-73 as novel aminotetrahydrofuran deriv.

in vivo

The pre-administration of Blarcamesine leads to a dose-dependent attenuation of the scopolamine induced alternation deficit, significant at 1 and 3 mg/kg. The pre-treatment with Blarcamesine hydrochloride attenuates the impairments of step-through latency, dose dependently and significantly at doses higher than 0.3 mg/kg[1]. The Blarcamesine hydrochloride treatment dose-dependently blocks the recognition memory deficit, with a significant effect measured at 1?mg/kg. One day after injections, the significant Aβ25-35-induced decrease in Akt phosphorylation is significantly attenuated by Blarcamesine hydrochloride at 0.1 and 1?mg/kg dose. Seven days after injections, Blarcamesine hydrochloride attenuates the decrease in Ser9 phosphorylation induced by the peptide at 0.3 and 1?mg/kg. The Blarcamesine hydrochloride treatment dose-dependently prevents the Aβ25-35-induced increase in Aβ1-42 content, with a significant effect at the highest dose tested[2].

IC 50

Sigma 1 Receptor

Anavex 2-73 Preparation Products And Raw materials

Raw materials

Preparation Products

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Anavex 2-73 Suppliers

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View Lastest Price from Anavex 2-73 manufacturers

Career Henan Chemical Co
Product
Anavex 2-73 195615-84-0
Price
US $1.00/g
Min. Order
1g
Purity
99.99%
Supply Ability
200kg
Release date
2019-12-24

195615-84-0, Anavex 2-73Related Search:

Tetrahydro-N-methyl-2,2-diphenyl-3-furanmethanamine hydrochloride salt

  • Anavex 2-73
  • AE-37 HYDROCHLORIDE
  • AN2/AVex-73 hydrochloride salt
  • AN2/AVEX-73 HCL SALT
  • AVex-73 hydrochloride
  • Anavex2-73 HCl
  • CS-2759
  • AE-37; AVEX-73; ANAVEX-2-73; ANAVEX-273; AE37; AVEX73; ANAVEX273; AE 37; AVEX 73; ANAVEX 2 73; ANAVEX 273; BLARCAMESINE
  • Blarcamesine
  • Anavex 2-73(ANAVEX2-73)
  • AVex-73 hydrochloride(AE-37)
  • Blarcamesine hydrochloride
  • AVex-73 hydrochL
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride salt
  • 1-(2,2-Diphenyltetrahydrofuran-3-yl)-N,N-dimethylmethanamine hydrochloride
  • Anavex 2-73 hydrochloride
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride
  • Inhibitor,Blarcamesine,Blarcamesine hydrochloride,inhibit,Sigma Receptor
  • AVex-73 HCl
  • Blarcamesine hydrochloride, 10 mM in DMSO
  • Tetrahydro-N,N-dimethyl-2,2-diphenyl-3-furanmethanamine hydrochloride98%
  • 195615-84-0
  • API