2-AMINO-5-NITRO-1H-BENZIMIDAZOLE
- Product Name
- 2-AMINO-5-NITRO-1H-BENZIMIDAZOLE
- CAS No.
- 6232-92-4
- Chemical Name
- 2-AMINO-5-NITRO-1H-BENZIMIDAZOLE
- Synonyms
- 6-Nitro-1H-benzo[d;2-AMINO-6-NITROBENZIMIDAZOLE;2-Amino-5-nitro-benzimidazole;2-AMINO-5-NITRO-1H-BENZIMIDAZOLE;2-amine-5-nitro-1H-benzimidazole;1H-Benzimidazol-2-amine,5-nitro-;5-Nitro-1H-benzimidazol-2-ylamine;6-nitro-1H-1,3-benzodiazol-2-amine;6-Nitro-1H-benzoimidazol-2-ylamine;6-Nitro-1H-benzo[d]iMidazol-2-aMine
- CBNumber
- CB5315176
- Molecular Formula
- C7H6N4O2
- Formula Weight
- 178.15
- MOL File
- 6232-92-4.mol
2-AMINO-5-NITRO-1H-BENZIMIDAZOLE Property
- Melting point:
- 222-223 °C (decomp)
- Boiling point:
- 478.5±37.0 °C(Predicted)
- Density
- 1.631±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- form
- powder to crystal
- pka
- 9.63±0.10(Predicted)
- color
- White to Yellow to Orange
- CAS DataBase Reference
- 6232-92-4(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H319Causes serious eye irritation
- Precautionary statements
-
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- A2934
- Product name
- 2-Amino-5-nitrobenzimidazole
- Packaging
- 250MG
- Price
- $206
- Updated
- 2025/07/31
- Product number
- A615055
- Product name
- 2-Amino-5-nitro-1h-benzimidazole
- Packaging
- 100mg
- Price
- $115
- Updated
- 2021/12/16
- Product number
- A615055
- Product name
- 2-Amino-5-nitro-1h-benzimidazole
- Packaging
- 500mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- A615055
- Product name
- 2-Amino-5-nitro-1h-benzimidazole
- Packaging
- 1g
- Price
- $515
- Updated
- 2021/12/16
- Product number
- 057540
- Product name
- 5-Nitro-1H-benzo[d]imidazol-2-amine
- Purity
- 98%
- Packaging
- 1g
- Price
- $188
- Updated
- 2021/12/16
2-AMINO-5-NITRO-1H-BENZIMIDAZOLE Chemical Properties,Usage,Production
Synthesis
506-68-3
99-56-9
6232-92-4
4-Nitrophthalimide (1.4 g, 9.1 mmol) was suspended in an aqueous solution (30 mL) of cyanogen bromide (0.97 g, 9.2 mmol) and heated to reflux for 7 hr. Upon completion of the reaction, the reaction mixture was cooled and neutralized with 25% NH4OH solution to pH 10-11. Subsequently, the precipitate formed was collected by filtration, washed with water, dried over air, and finally recrystallized from hot water to give 2-amino-6-nitrobenzimidazole as orange-yellow shiny crystals. Yield: 1.28 g (91.4%); Melting point: 245-247 °C. 1H NMR (400 MHz, DMSO-d6, δ ppm): 8.10 (d, 1H, J = 2.2 Hz, ArH), 7.90 (dd, 1H, J = 8.70, 2.2 Hz, ArH), 7.20 (d, 1H, J = 8.7 Hz, ArH). 6.90 (s, 2H, NH2). 13C NMR (400 MHz, DMSO-d6, δ ppm): 158.91, 139.92, 136.67, 116.50, 111.16, 106.16. IR (KBr, cm-1): 3514, 3457 (NH stretching vibration), 3092 (aromatic CH stretching vibration), 1658 (C=NH stretching vibration), 1658 (C=NH stretching vibration). ), 1658 (C=N ring stretching vibration), 1587, 1507 (skeletal vibrational bands), 1421 (asymmetric N=O stretching vibration), 1471 (NH shear vibration), 1336 (symmetric N=O stretching vibration), 876 (NH wobble vibration).MS (+ESI-QTOF): m/z calculated value C7H6N4O2 [M+H]+ 179.14, measured value 179.1 (100%).
References
[1] European Journal of Medicinal Chemistry, 1990, vol. 25, # 4, p. 309 - 319
[2] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 2, p. 663 - 674
[3] Angewandte Chemie - International Edition, 2012, vol. 51, # 21, p. 5226 - 5229
[4] Bioorganic Chemistry, 2018, vol. 80, p. 24 - 35
[5] Patent: EP1674466, 2006, A1. Location in patent: Page/Page column 25
2-AMINO-5-NITRO-1H-BENZIMIDAZOLE Preparation Products And Raw materials
Raw materials
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View Lastest Price from 2-AMINO-5-NITRO-1H-BENZIMIDAZOLE manufacturers
- Product
- 2-AMINO-5-NITRO-1H-BENZIMIDAZOLE 6232-92-4
- Price
- US $0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1000kg
- Release date
- 2025-07-05
- Product
- 2-AMINO-5-NITRO-1H-BENZIMIDAZOLE 6232-92-4
- Price
- US $1.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 200KG
- Release date
- 2018-12-23