SLF Exclusive

Product Name: SLF Exclusive
CAS No.: 195513-96-3
Chemical Name: SLF Exclusive
Synonyms: SLF Exclusive;IIDSDBBDZNDWCN-BJKOFHAPSA-N;(R)-1-(3-Aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate;(1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate;2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-
CBNumber: CB53152987
Molecular Formula: C30H40N2O6
Formula Weight: 524.65
MOL File: 195513-96-3.mol

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SLF Exclusive Property

Boiling point:: 656.9±65.0 °C(Predicted)
Density: 1.161±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 30 mg/ml; Ethanol:PBS (pH 7.2)(1:3): .2 mg/ml
pka: 4.14±0.10(Predicted)
form: Oil
color: Light yellow to yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P337+P313IF eye irritation persists: Get medical advice/attention.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10007974
Product name: SLF
Purity: ≥98%
Packaging: 5mg
Price: $92
Updated: 2024/03/01

Cayman Chemical

Product number: 10007974
Product name: SLF
Purity: ≥98%
Packaging: 10mg
Price: $174
Updated: 2024/03/01

Cayman Chemical

Product number: 10007974
Product name: SLF
Purity: ≥98%
Packaging: 50mg
Price: $719
Updated: 2024/03/01

Cayman Chemical

Product number: 10007974
Product name: SLF
Purity: ≥98%
Packaging: 100mg
Price: $1204
Updated: 2024/03/01

ChemScene

Product number: CS-0064537
Product name: SLF
Purity: 98.60%
Packaging: 5mg
Price: $75
Updated: 2021/12/16

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SLF Exclusive Chemical Properties,Usage,Production

Uses

SLF is a synthetic ligand for FK506-binding protein (FKBP) with an affinity of 3.1 μM for FKBP51 and an IC50 of 2.6 μM for FKBP12. SLF can be used in the synthesis of PROTAC[1][2][3].

References

[1] Kolos JM, et al. FKBP Ligands-Where We Are and Where to Go? Front Pharmacol. 2018 Dec 5;9:1425. DOI:10.3389/fphar.2018.01425
[2] Wu X, et al. Creating diverse target-binding surfaces on FKBP12: synthesis and evaluation of a rapamycin analogue library. ACS Comb Sci. 2011 Sep 12;13(5):486-95. DOI:10.1021/co200057n
[3] Zhang X, et al. Electrophilic PROTACs that degrade nuclear proteins by engaging DCAF16. Nat Chem Biol. 2019 Jul;15(7):737-746. DOI:10.1038/s41589-019-0279-5

SLF Exclusive Preparation Products And Raw materials

Raw materials

Preparation Products

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SLF Exclusive Suppliers

China 24 United States 5 Global 29

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
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Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
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Sichuan Wei Keqi Biological Technology Co., Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Beijing Jin Ming Biotechnology Co., Ltd.

Tel: 010-60605840 18892239720
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Shanghai Hongye Biotechnology Co. Ltd

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Fan De(Beijing) Biotechnology Co., Ltd.

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Jilin Province Woda Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
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BOC Sciences

Tel: +1-631-485-4226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 19552
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195513-96-3, SLF ExclusiveRelated Search:

SLF Exclusive

IIDSDBBDZNDWCN-BJKOFHAPSA-N

2-Piperidinecarboxylic acid, 1-(3,3-dimethyl-1,2-dioxopentyl)-, (1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl ester, (2S)-

(R)-1-(3-Aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

(1R)-1-(3-aminophenyl)-3-(3,4-dimethoxyphenyl)propyl (2S)-1-(3,3-dimethyl-2-oxopentanoyl)piperidine-2-carboxylate

195513-96-3