ChemicalBook > CAS DataBase List > CID5721353

CID5721353

Product Name
CID5721353
CAS No.
301356-95-6
Chemical Name
CID5721353
Synonyms
CID5721353;BCL6 inhibitor;79-6（CID5721353）;CID-5721353;CID 5721353;CID5721353 BDL6 inhribitor;BCL6 inhibitor(CID5721353);CID5721353, BCL6 inhibitor;79-6 (CID5721353， BCL6 inhibitor);CID 5721353;CID-5721353;CID 5721353;Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
CBNumber
CB53159456
Molecular Formula
C15H9BrN2O6S2
Formula Weight
457.28
MOL File
301356-95-6.mol
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CID5721353 Property

Density 
2.06±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
Solid
pka
3.02±0.23(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22967
Product name
CID-5721353
Packaging
1mg
Price
$32
Updated
2024/03/01
Cayman Chemical
Product number
22967
Product name
CID-5721353
Packaging
5mg
Price
$70
Updated
2024/03/01
Cayman Chemical
Product number
22967
Product name
CID-5721353
Packaging
10mg
Price
$109
Updated
2024/03/01
Cayman Chemical
Product number
22967
Product name
CID-5721353
Packaging
25mg
Price
$190
Updated
2024/03/01
AK Scientific
Product number
6486CL
Product name
2-[5-(5-Bromo-2-oxoindol-3-yl)-4-hydroxy-2-sulfanylidene-1,3-thiazol-3-yl]butanedioicacid
Packaging
5mg
Price
$313
Updated
2021/12/16
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CID5721353 Chemical Properties,Usage,Production

Description

CID-5721353 is an inhibitor of the transcriptional repressor B cell lymphoma 6 (Bcl-6; Ki = 147 μM). It is selective for Bcl-6 over Kaiso, hypermethylated in cancer 1 (HIC1), and promyelocytic leukemia zinc finger (PLZF) at 50 μM. CID-5721353 is cytotoxic against Bcl-6-dependent SU-DLH-6, SU-DLH-4, Farage, OCI-LY7, OCI-LY1, and OCI-LY10 diffuse large B cell lymphoma (DLBCL) cells (GI50s = 0.024-0.936 mM) but not Bcl-6-independent Toledo or OCI-LY4 DLBCL cells (GI50 = >15 mM for both). It increases expression of the Bcl-6 target genes ATR, TP53, CD69, p21, and CD44 in SU-DLH-6 and SU-DHL-4 cells when used at a concentration of 50 μM. CID-5721353 (50 mg/kg) reduces tumor growth in OCI-LY7 and SU-DHL-6 mouse xenograft models.

CID5721353 Preparation Products And Raw materials

Raw materials

Preparation Products

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CID5721353 Suppliers

China 47 United States 6 USA 1 Global 54
Dalian Meilun Biotech Co., Ltd.
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View Lastest Price from CID5721353 manufacturers

Career Henan Chemical Co
Product
CID5721353 301356-95-6
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

301356-95-6, CID5721353Related Search:


  • CID5721353
  • CID5721353, BCL6 inhibitor
  • BCL6 inhibitor(CID5721353)
  • CID5721353 BDL6 inhribitor
  • CID-5721353;CID 5721353
  • 79-6 (CID5721353， BCL6 inhibitor)
  • CID 5721353;CID-5721353;CID 5721353
  • 2-(5-(5-bromo-2-oxoindolin-3-ylidene)-4-oxo-2-thioxothiazolidin-3-yl)succinic acid
  • BCL6 inhibitor
  • Butanedioic acid, 2-[5-(5-bromo-1,2-dihydro-2-oxo-3H-indol-3-ylidene)-4-oxo-2-thioxo-3-thiazolidinyl]-
  • Apoptosis,Inhibitor,CID5721353,Bcl-2 Family,CID-5721353,inhibit,CID 5721353
  • 79-6（CID5721353）
  • 301356-95-6
  • C15H9BrN2O6S2
  • API