4-(TERT-BUTYL)-2-NITROANILINE

Product Name: 4-(TERT-BUTYL)-2-NITROANILINE
CAS No.: 6310-19-6
Chemical Name: 4-(TERT-BUTYL)-2-NITROANILINE
Synonyms: BUTTPARK 52\04-96;2-Nitro-4-tert-butylaniline;4-(TERT-BUTYL)-2-NITROANILINE;4-tert-Butyl-2-nitrobenzenaMine;4-tert-Butyl-2-nitro-phenylaMine;2-Amino-5-(tert-butyl)nitrobenzene;4-(1,1-Dimethylethyl)-2-nitrobenzenamine;Benzenamine, 4-(1,1-dimethylethyl)-2-nitro-;4-(TERT-BUTYL)-2-NITROANILINE ISO 9001：2015 REACH
CBNumber: CB5315989
Molecular Formula: C10H14N2O2
Formula Weight: 194.23
MOL File: 6310-19-6.mol

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4-(TERT-BUTYL)-2-NITROANILINE Property

Melting point:: 101-104°C
Boiling point:: 302.8±30.0 °C(Predicted)
Density: 1.140±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
form: crystalline powder
pka: 0.43±0.10(Predicted)
color: Orange
CAS DataBase Reference: 6310-19-6(CAS DataBase Reference)

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Safety

Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36/37/39
RIDADR: 2811
HazardClass: 6.1
PackingGroup: Ⅱ
HS Code: 2921420090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H225Highly Flammable liquid and vapour

H290May be corrosive to metals

H314Causes severe skin burns and eye damage

H330Fatal if inhaled

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P234Keep only in original container.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P363Wash contaminated clothing before reuse.

P370+P378In case of fire: Use … for extinction.

P390Absorb spillage to prevent material damage.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

P406Store in corrosive resistant/… container with a resistant inner liner.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S192341
Product name: 4-TERT-BUTYL-2-NITRO-PHENYLAMINE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $30.7
Updated: 2025/07/31

TRC

Product number: B695125
Product name: 4-(tert-Butyl)-2-nitroaniline
Packaging: 250mg
Price: $45
Updated: 2021/12/16

Oakwood

Product number: 024552
Product name: 4-tert-Butyl-2-nitroaniline
Packaging: 1g
Price: $10
Updated: 2021/12/16

Apolloscientific

Product number: OR4982
Product name: 4-(tert-Butyl)-2-nitroaniline
Packaging: 1g
Price: $15
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4755-1-X7
Product name: 4-(tert-Butyl)-2-nitroaniline
Packaging: 1g
Price: $16
Updated: 2021/12/16

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4-(TERT-BUTYL)-2-NITROANILINE Chemical Properties,Usage,Production

Uses

4-(tert-Butyl)-2-nitroaniline is an organic compound commonly used in organic synthesis, especially as a synthetic intermediate in the pharmaceutical and dye industries.

Synthesis

40655-37-6

6310-19-6

General procedure for the synthesis of 4-tert-butyl-2-nitroaniline from N-(4-tert-butyl-2-nitrophenyl)acetamide: Methanol (13.5 L) and N-(4-tert-butyl-2-nitrophenyl)acetamide (7.0 kg, 29.6 mol) were added to the reactor. The mixture was stirred for 10 min, then a methanol solution of 30% sodium methanol (6.49 L, 35.5 mol) was slowly added at room temperature. The mixture was slowly heated to reflux and held at this temperature for 2 hours. Upon completion of the reaction, the methanol was vacuum distilled to dryness at 50-55°C and the solid was cooled to room temperature. The residue was stirred in water (35 L) for 1 h. The solid was collected by filtration, washed with water (14 L) and dried at 45-50 °C to give 5.3 kg of 4-tert-butyl-2-nitroaniline. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 1.27 (s, 9H), 5.95 (br s, 2H), 6.76 (d, 1H), 7.43 (d, 1H), 8.08 (s, 1H).

References

[1] Journal of the American Chemical Society, 2012, vol. 134, # 3, p. 1528 - 1535
[2] Journal of Organic Chemistry, 1970, vol. 35, p. 917 - 923
[3] Journal of Medicinal Chemistry, 1995, vol. 38, # 25, p. 4906 - 4916
[4] Patent: WO2011/47315, 2011, A1. Location in patent: Page/Page column 51
[5] Patent: WO2013/114250, 2013, A1. Location in patent: Page/Page column 181

4-(TERT-BUTYL)-2-NITROANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(TERT-BUTYL)-2-NITROANILINE Suppliers

Belgium 1 China 108 France 1 Germany 2 India 1 The Netherlands 1 United Kingdom 10 United States 15 Global 139

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View Lastest Price from 4-(TERT-BUTYL)-2-NITROANILINE manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 4-tert-butyl-2-nitroaniline 6310-19-6
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-07

Henan Fengda Chemical Co., Ltd

Product: 4-(TERT-BUTYL)-2-NITROANILINE 6310-19-6
Price: US $100.00-1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2023-12-26

Henan Bao Enluo International TradeCo.，LTD

Product: 4-tert-butyl-2-nitroaniline 6310-19-6
Price: US $50.00/kg
Min. Order: 1kg
Purity: 99.9%
Supply Ability: 10000MT
Release date: 2023-08-15

6310-19-6, 4-(TERT-BUTYL)-2-NITROANILINERelated Search:

4-tert-Butylaniline 2-TERT-BUTYL-4-NITROANILINE 2-TERT-BUTYL-5-NITROANILINE 2-tert-butyl-3-nitroaniline 2-tert-butyl-6-nitroaniline 3-TERT-BUTYL-4-NITROANILINE N-tert-Butyl-4-nitroaniline 5-TERT-BUTYL-2-NITROANILINE N-tert-Butyl-3-nitroaniline N-[4-(TERT-BUTYL)-2-NITROPHENYL]-2-CHLOROACETAMIDE 2,4-ditert-butyl-6-nitroaniline 1-(4-tert-butyl-2-nitrophenyl)hydrazine BUTRALIN 4-(TERT-BUTYL)-2-NITROANILINE

BUTTPARK 52\04-96

4-(TERT-BUTYL)-2-NITROANILINE

Benzenamine, 4-(1,1-dimethylethyl)-2-nitro-

2-Nitro-4-tert-butylaniline

4-(1,1-Dimethylethyl)-2-nitrobenzenamine

4-tert-Butyl-2-nitrobenzenaMine

2-Amino-5-(tert-butyl)nitrobenzene

4-tert-Butyl-2-nitro-phenylaMine

4-(TERT-BUTYL)-2-NITROANILINE ISO 9001：2015 REACH

6310-19-6

6310-19-0