ChemicalBook > CAS DataBase List > Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Product Name
- Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- CAS No.
- 82419-34-9
- Chemical Name
- Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Synonyms
- Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate;"(S)-ethyl 8,9-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate";9, 10-Difluoro-3-methyl-7-oxo-2,3-dihydro-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid ethyl ester;ethyl 6,7-difluoro-2-methyl-10-oxo-4-oxa-1-azatricyclo[7.3.1.05,13]trideca-5(13),6,8,11-tetraene-11-carboxylate
- CBNumber
- CB53161983
- Molecular Formula
- C15H13F2NO4
- Formula Weight
- 309.26
- MOL File
- 82419-34-9.mol
More
Less
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Property
- Melting point:
- 261 °C(Solv: ethanol (64-17-5))
- Boiling point:
- 442.2±45.0 °C(Predicted)
- Density
- 1.43±0.1 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- -3.62±0.60(Predicted)
More
Less
N-Bromosuccinimide Price
AK Scientific
- Product number
- 2845CL
- Product name
- Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Packaging
- 100mg
- Price
- $109
- Updated
- 2021/12/16
AK Scientific
- Product number
- 2845CL
- Product name
- Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Packaging
- 250mg
- Price
- $139
- Updated
- 2021/12/16
Alichem
- Product number
- 82419349
- Product name
- Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Packaging
- 250mg
- Price
- $151.2
- Updated
- 2021/12/16
Ambeed
- Product number
- A419532
- Product name
- Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $252
- Updated
- 2021/12/16
Crysdot
- Product number
- CD11051712
- Product name
- Ethyl9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
- Purity
- 97%
- Packaging
- 1g
- Price
- $347
- Updated
- 2021/12/16
More
Less
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Chemical Properties,Usage,Production
Synthesis
74-96-4
82419-35-0
82419-34-9
The general procedure for the synthesis of ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate from ethyl bromide and fluorozinecarboxylic acid was as follows: 40 g of fluorozinecarboxylic acid was suspended in 200 mL of N,N-dimethylformamide, and ethyl bromide and 21.6 g of potassium carbonate were subsequently added to form a white suspension. The reaction mixture was stirred at 50 °C for 5 hours. Upon completion of the reaction, the mixture was cooled to room temperature and filtered to collect 60 g of white solid. The solid was dissolved in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol and stirred at 40 °C. After filtration, the undissolved solid was dissolved again in a solvent mixture of 200 mL of dichloromethane and 200 mL of methanol, stirred at 40°C and filtered. The filtrates were combined and concentrated and dried by rotary evaporator. To the dried product, 300 mL of ether was added, stirred at room temperature and filtered to obtain a white solid, i.e., target compound II.
References
[1] Patent: CN107586302, 2018, A. Location in patent: Paragraph 0022; 0023; 0024
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate Suppliers
- Tel
- 0755-0755-66853366 13670046396
- Fax
- 0755-28363542
- sales@chem-strong.com
- Country
- China
- ProdList
- 18333
- Advantage
- 56
- Tel
- 025-83453382-8005
- Fax
- 025-83453382
- sale@parabiochem.com
- Country
- China
- ProdList
- 9595
- Advantage
- 55
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 025-66061636 18013972705
- Fax
- (3)02557626880
- qqyang@aikonchem.com
- Country
- China
- ProdList
- 15814
- Advantage
- 58
- Tel
- 15589964716
- Fax
- qq：3360232875
- 15253102672@163.com
- Country
- China
- ProdList
- 211
- Advantage
- 58
- Tel
- 0371-63315541 13323832564
- Fax
- QQ:3001332135
- 3001332135@qq.com
- Country
- China
- ProdList
- 9972
- Advantage
- 58
- Tel
- 18081075745
- chemflowtech@sina.com
- Country
- China
- ProdList
- 1886
- Advantage
- 58
- Tel
- +86-0571-85134551
- Fax
- 008657185134895
- sales@afinechem.com
- Country
- China
- ProdList
- 15109
- Advantage
- 58
- Tel
- +86-0371-86658258 +8613203830695
- Fax
- 0371-86658258
- laboratory@coreychem.com
- Country
- China
- ProdList
- 30229
- Advantage
- 58
- Tel
- 15151934985
- sales@yingsapharm.com
- Country
- China
- ProdList
- 5183
- Advantage
- 58
More
Less
View Lastest Price from Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate manufacturers
Career Henan Chemical Co
- Product
- Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate 82419-34-9
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-10
82419-34-9, Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylateRelated Search:
Ofloxacin EP Impurity C
OFLOXACIN RELATED COMPOUND A (25 MG) ((RS)-9-FLUORO-2,3-DIHYDRO-3-METHYL-7-OXO-10-(PIPERA-ZIN-1 -YL)-7H-PYRIDO[1,2,3-DE]-1,4-BENZOXAZINE-6-CARBOXYLIC ACID)
Ofloxacin
OFLOXACIN N-OXIDE (MIXTURE OF DIASTEREOMERS)
9-Piperazino Ofloxacin