Azido-PEG4- Boc-Hydrazide

Product Name: Azido-PEG4- Boc-Hydrazide
CAS No.: 1919045-01-4
Chemical Name: Azido-PEG4- Boc-Hydrazide
Synonyms: Azido-PEG4-hydrazide-Boc;Azido-PEG4- Boc-Hydrazide;Azido-PEG4-t-Boc-Hydrazide;N'-Boc-1-azido-3,6,9,12-tetraoxapentadecane-15-hydrazide;tert-Butyl 18-azido-4-oxo-7,10,13,16-tetraoxa-2,3-diazaoctadecanoate
CBNumber: CB53162874
Molecular Formula: C16H31N5O7
Formula Weight: 405.44664
MOL File: 1919045-01-4.mol

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Azido-PEG4- Boc-Hydrazide Property

storage temp.: Storage temp. 2-8°C
form: Viscous Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23197
Product name: Azido-PEG4-t-Boc-hydrazide
Purity: 98%
Packaging: 100mg
Price: $320
Updated: 2021/12/16

BroadPharm

Product number: BP-23197
Product name: Azido-PEG4-t-Boc-hydrazide
Purity: 98%
Packaging: 500mg
Price: $720
Updated: 2021/12/16

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Azido-PEG4- Boc-Hydrazide Chemical Properties,Usage,Production

Description

Azido-PEG4-t-Boc-hydrazide is a Boc-protected PEG linker containing an azide group (N3). The hydrophilic PEG spacer increases solubility in aqueous media. The azide group can react with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage. The Boc site can be deprotected under mild acidic conditions to form a reactive hydrazide, which can then be coupled with various carbonyl groups.

Uses

Azido-PEG4-hydrazide-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG4-hydrazide-Boc is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

Azido-PEG4- Boc-Hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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Azido-PEG4- Boc-Hydrazide Suppliers

China 32 United States 3 Global 35

Bide Pharmatech Ltd.

Tel: 400-400-164-7117 18317119277
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 40000
Advantage: 60

Mashilabs (Shanghai) Co.,Ltd.

Tel: 19916721580
Fax: QQ：3154870176
Email: mafarm@126.com
Country: China
ProdList: 4539
Advantage: 58

Jilin Chinese Academy of Sciences - Yanshen Technology Co., Ltd

Tel: 0431-80534353 19917294565
Email: et@chemextension.com
Country: China
ProdList: 3828
Advantage: 55

Shanghai EFE Biological Technology Co., Ltd.

Tel: 021-65675885 18964387627
Fax: 021-65675885
Email: info@efebio.com
Country: China
ProdList: 9803
Advantage: 58

Jinan elephant international trading co., LTD

Tel
Fax: -
Email: 13006575422@163.com
Country: China
ProdList: 6355
Advantage: 58

SHANGHAI FDC-CHEMICAL CO.,LTD

Tel: 021-61469567 13482353728
Fax: 021-61161605
Email: sales@fdc-chemical.com
Country: China
ProdList: 9964
Advantage: 58

Xi'an Confluore Biological Technology Co., Ltd.

Tel: +86-156-80926068 +86-15680926068
Email: 1924344760@qq.com
Country: China
ProdList: 4952
Advantage: 58

Zhengzhou Acme Chemical Co., Ltd.

Tel: 0371-037163312495,13303845143 13303845143
Fax: QQ3001379618
Email: 3001379618@qq.com
Country: China
ProdList: 10197
Advantage: 58

Alpha Biopharmaceuticals Co., Ltd

Tel: 0411-39042497
Fax: 0411-39042693
Email: sales@alphabiopharm.com
Country: China
ProdList: 1951
Advantage: 58

TargetMol Chemicals Inc.

Tel: +1-781-999-5354; +17819995354
Email: marketing@targetmol.com
Country: United States
ProdList: 32467
Advantage: 58

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View Lastest Price from Azido-PEG4- Boc-Hydrazide manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: Azido-PEG4-hydrazide-Boc 1919045-01-4
Price: US $0.00/g
Min. Order: 1g
Purity: >98.00%
Supply Ability: 1g
Release date: 2024-03-23

1919045-01-4, Azido-PEG4- Boc-HydrazideRelated Search:

Azido-PEG4- Boc-Hydrazide

Azido-PEG4-t-Boc-Hydrazide

Azido-PEG4-hydrazide-Boc

tert-Butyl 18-azido-4-oxo-7,10,13,16-tetraoxa-2,3-diazaoctadecanoate

N'-Boc-1-azido-3,6,9,12-tetraoxapentadecane-15-hydrazide

1919045-01-4