NH-(PEG1-OH)2

Product Name: NH-(PEG1-OH)2
CAS No.: 54384-47-3
Chemical Name: NH-(PEG1-OH)2
Synonyms: NH-bis-PEG2;NH-(PEG1-OH)2;NH-bis(PEG1-OH);Ethanol, 2,2'-[iminobis(2,1-ethanediyloxy)]bis-;2-[2-[2-(2-hydroxyethoxy)ethylamino]ethoxy]ethanol;2,2’-[[Azanediylbis(ethane-2,1-diyl)]bis(oxy)]diethanol;2-(2-{[2-(2-hydroxyethoxy)ethyl]amino}ethoxy)ethan-1-ol
CBNumber: CB53163073
Molecular Formula: C8H19NO4
Formula Weight: 193.24
MOL File: 54384-47-3.mol

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NH-(PEG1-OH)2 Property

Boiling point:: 128 °C(Press: 0.02 Torr)
Density: 1.090±0.06 g/cm3(Predicted)
solubility: Soluble in Water, DMSO, DCM, DMF
pka: 14.09±0.10(Predicted)
form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H315Causes skin irritation

H318Causes serious eye damage

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23224
Product name: NH-bis(PEG1-OH)
Purity: 98%
Packaging: 250mg
Price: $330
Updated: 2021/12/16

BroadPharm

Product number: BP-23224
Product name: NH-bis(PEG1-OH)
Purity: 98%
Packaging: 500mg
Price: $540
Updated: 2021/12/16

BroadPharm

Product number: BP-23224
Product name: NH-bis(PEG1-OH)
Purity: 98%
Packaging: 1g
Price: $780
Updated: 2021/12/16

AK Scientific

Product number: 3741CT
Product name: 2,2'-((Azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol
Packaging: 500mg
Price: $896
Updated: 2021/12/16

AK Scientific

Product number: 3741CT
Product name: 2,2'-((Azanediylbis(ethane-2,1-diyl))bis(oxy))diethanol
Packaging: 1g
Price: $1121
Updated: 2021/12/16

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NH-(PEG1-OH)2 Chemical Properties,Usage,Production

Description

NH-bis(PEG1-OH) can be used to conjugate with carboxylic acid in the presence of HATU or EDC

Biological Activity

NH-bis(PEG1-OH) is a non-cleavable 2-unit PEG ADC linker for the synthesis of antibody drug conjugates (ADCs). It is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.

in vitro

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.

target

Non-cleavable

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PEGs

NH-(PEG1-OH)2 Preparation Products And Raw materials

Raw materials

Preparation Products

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NH-(PEG1-OH)2 Suppliers

China 31 United States 4 Global 35

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View Lastest Price from NH-(PEG1-OH)2 manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: NH-bis(PEG1-OH) 54384-47-3
Price: US $0.00/g
Min. Order: 10g
Purity: >95.00%
Supply Ability: 10g
Release date: 2024-03-28

54384-47-3, NH-(PEG1-OH)2Related Search:

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2-[2-[2-(2-hydroxyethoxy)ethylamino]ethoxy]ethanol

54384-47-3