N-methyl-N'-(propargyl-PEG4)-Cy5
- Product Name
- N-methyl-N'-(propargyl-PEG4)-Cy5
- CAS No.
- 2107273-04-9
- Chemical Name
- N-methyl-N'-(propargyl-PEG4)-Cy5
- Synonyms
- N-methyl-N'-(propargyl-PEG4)-Cy5;2-(5-(3,3-dimethyl-1-(3,6,9,12-tetraoxapentadec-14-yn-1-yl)indolin-2-ylidene)penta-1,3-dien-1-yl)-1,3,3-trimethyl-3H-indol-1-ium chloride
- CBNumber
- CB53163093
- Molecular Formula
- C37H47ClN2O4
- Formula Weight
- 619.24
- MOL File
- 2107273-04-9.mol
N-methyl-N'-(propargyl-PEG4)-Cy5 Property
- solubility
- Soluble in DMSO, DMF, DCM, low solubility in water
N-Bromosuccinimide Price
- Product number
- BP-23013
- Product name
- N-methyl-N'-(propargyl-PEG4)-Cy5
- Purity
- 97%
- Packaging
- 1mg
- Price
- $150
- Updated
- 2021/12/16
- Product number
- BP-23013
- Product name
- N-methyl-N'-(propargyl-PEG4)-Cy5
- Purity
- 97%
- Packaging
- 5mg
- Price
- $450
- Updated
- 2021/12/16
- Product number
- BP-23013
- Product name
- N-methyl-N'-(propargyl-PEG4)-Cy5
- Purity
- 97%
- Packaging
- 10mg
- Price
- $680
- Updated
- 2021/12/16
N-methyl-N'-(propargyl-PEG4)-Cy5 Chemical Properties,Usage,Production
Description
N-methyl-N'-(propargyl-PEG4)-Cy5 is a cyanine linker with excitation/emmission maximum 649/667 nm containing an alkyne group, which enables Click Chemistry to attach deeply colored and photostable Cyanine fluorophore to various molecules.
Uses
N-methyl-N'-(propargyl-PEG4)-Cy5 (chloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-methyl-N'-(propargyl-PEG4)-Cy5 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-methyl-N'-(propargyl-PEG4)-Cy5 Preparation Products And Raw materials
Raw materials
Preparation Products
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