AUNP-12

ChemicalBook > CAS DataBase List > AUNP-12

Product Name: AUNP-12
CAS No.: 1353563-85-5
Chemical Name: AUNP-12
Synonyms: AUR 012;AUNP-12;NP-12 TFA;Aurigene-012;Aurigene NP-12;AURIGENE-012;AUR 012;L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-
CBNumber: CB53168755
Molecular Formula: C142H226N40O48
Formula Weight: 3261.55
MOL File: 1353563-85-5.mol

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AUNP-12 Property

Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Water: Soluble
form: A solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 28053
Product name: AUNP-12
Packaging: 1mg
Price: $153
Updated: 2024/03/01

Cayman Chemical

Product number: 28053
Product name: AUNP-12
Packaging: 5mg
Price: $420
Updated: 2024/03/01

Biorbyt Ltd

Product number: orb611287
Product name: AUNP-12
Purity: >98%
Packaging: 100mg
Price: $1949.9
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611287
Product name: AUNP-12
Purity: >98%
Packaging: 250mg
Price: $3282.7
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb611287
Product name: AUNP-12
Purity: >98%
Packaging: 1g
Price: $5803.8
Updated: 2021/12/16

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AUNP-12 Chemical Properties,Usage,Production

Biological Activity

AUNP-12 (Aur-012, Aurigene-012, Aurigene NP-12), a novel immune checkpoint modulator, is an inhibitor of PD-1 signaling pathway.

in vitro

In hPDL2-expressing HEK293 cells, AUNP-12 inhibited the binding of PD1 to PDL2 with EC50 of 0.72 nM; in hPDL1-expressing MDA-MB231 cells, in PBMC proliferation assay, EC50 was 0.41 nM.

target

Target	Value
PD-L1 (Cell-free assay)

AUNP-12 Preparation Products And Raw materials

Raw materials

Preparation Products

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AUNP-12 Suppliers

China 39 United States 4 Global 43

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1353563-85-5, AUNP-12Related Search:

CHOLESTEROL ESTERASE

AUNP-12

AUR 012

Aurigene-012

AURIGENE-012;AUR 012

L-α-Glutamine, N2,N6-bis(L-seryl-L-asparaginyl-L-threonyl-L-seryl-L-α-glutamyl-L-seryl-L-phenylalanyl)-L-lysyl-L-phenylalanyl-L-arginyl-L-valyl-L-threonyl-L-glutaminyl-L-leucyl-L-alanyl-L-prolyl-L-lysyl-L-alanyl-L-glutaminyl-L-isoleucyl-L-lysyl-

Aurigene NP-12

NP-12 TFA

1353563-85-5

C142H226N40O48