ChemicalBook > CAS DataBase List > 4-hydroxy-3-phenyl-naphthalene-1,2-dione
4-hydroxy-3-phenyl-naphthalene-1,2-dione
- Product Name
- 4-hydroxy-3-phenyl-naphthalene-1,2-dione
- CAS No.
- 1150-59-0
- Chemical Name
- 4-hydroxy-3-phenyl-naphthalene-1,2-dione
- Synonyms
- NSC 102533;Antimalarial agent 14;Antimalarial agent 14, 10 mM in DMSO;2-Hydroxy-3-phenyl-1,4-naphthoquinone;2-hydroxy-3-phenylnaphthalene-1,4-dione;4-hydroxy-3-phenyl-naphthalene-1,2-dione;1,4-Naphthalenedione, 2-hydroxy-3-phenyl-;2-hydroxy-3-phenyl-1,4-dihydronaphthalene-1,4-dione;4-hydroxy-3-phenyl-naphthalene-1,2-dione|||2-Hydroxy-3-phenyl-1,4-naphthoquinone;low cytotoxicity,inhibit,Antimalarial agent-14,P. falciparum,Mitochondrial Metabolism,Inhibitor,Antimalarial agent 14,mitochondrial electron transport,NSC 102533,Antimalarial agent14
- CBNumber
- CB53178985
- Molecular Formula
- C16H10O3
- Formula Weight
- 250.25
- MOL File
- 1150-59-0.mol
More
Less
4-hydroxy-3-phenyl-naphthalene-1,2-dione Property
- Melting point:
- 146 °C
- Boiling point:
- 440.5±45.0 °C(Predicted)
- Density
- 1.392±0.06 g/cm3(Predicted)
- solubility
- DMSO: Sparingly Soluble: 1-10 mg/mL
Ethanol: Slightly Soluble: 0.1-1 mg/mL - form
- Solid
- pka
- 4.26±0.10(Predicted)
- color
- Yellow to brown
More
Less
N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- CHM1043081
- Product name
- 2-HYDROXY-3-PHENYL-1,4-NAPHTHOQUINONE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $500.39
- Updated
- 2021/12/16
More
Less
4-hydroxy-3-phenyl-naphthalene-1,2-dione Chemical Properties,Usage,Production
Uses
Antimalarial agent 14 (Compound N3) is a potent inhibitor of mitochondrial electron transport. Antimalarial agent 14 can serve as an anti-malarial agent[1].
IC 50
Plasmodium
References
[1] Schuck DC, et al. Biological evaluation of hydroxynaphthoquinones as anti-malarials. Malar J. 2013 Jul 10;12:234. DOI:10.1186/1475-2875-12-234
[2] R X FARIA. 1,4-Naphthoquinones potently inhibiting P2X7 receptor activity.[J]. European Journal of Medicinal Chemistry, 2018, 143: 1361-1372. DOI: 10.1016/j.ejmech.2017.10.033
[3] MARCELO A STRAUCH. Lapachol and synthetic derivatives: in vitro and in vivo activities against Bothrops snake venoms.[J]. ACS Applied Bio Materials, 2019: e0211229. DOI: 10.1371/journal.pone.0211229
4-hydroxy-3-phenyl-naphthalene-1,2-dione Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
4-hydroxy-3-phenyl-naphthalene-1,2-dione Suppliers
- Tel
- 13621943973
- Fax
- -
- sales@shjiyipharmatech.com
- Country
- China
- ProdList
- 1166
- Advantage
- 55
- Tel
- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
- Country
- China
- ProdList
- 9803
- Advantage
- 58
- Tel
- 021-61312847; 18021002903
- Fax
- QQ:3008007432
- 3008007409@qq.com
- Country
- China
- ProdList
- 71826
- Advantage
- 60
- Tel
- 177-54423994 17754423994
- Fax
- QQ:2853530913
- 2853530910@QQ.com
- Country
- China
- ProdList
- 8000
- Advantage
- 62
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9186
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- 18696571988
- Fax
- +86 (23) 6777-0220
- amy.lei@chemieliva.com
- Country
- China
- ProdList
- 1555
- Advantage
- 60
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32470
- Advantage
- 58
- Tel
- +1-708-310-1919 +1-13798911105
- Fax
- 708-557-7486
- sales@invivochem.cn
- Country
- United States
- ProdList
- 6391
- Advantage
- 58
- Tel
- 13621943973; 13621943973
- sales@jamxmpharmatech.com
- Country
- China
- ProdList
- 1169
- Advantage
- 58
More
Less
View Lastest Price from 4-hydroxy-3-phenyl-naphthalene-1,2-dione manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- 4-hydroxy-3-phenyl-naphthalene-1,2-dione 1150-59-0
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 10 tons
- Release date
- 2024-08-17