3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE

Product Name: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE
CAS No.: 198821-79-3
Chemical Name: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE
Synonyms: 3-Methoxy-4-(oxazol-5-yl);3-Methoxy-4-(5-oxazolyl)aniline;3-Methoxy-4-(oxazol-5-yl)aniline;5-(4-Amino-2-methoxyphenyl)oxazole;3-Methoxy-4-(5-oxazolyl)benzenamine;3-Methoxy-4-(5-oxazolyl)aniline, 97%;3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE;BenzenaMine, 3-Methoxy-4-(5-oxazolyl)-
CBNumber: CB5318849
Molecular Formula: C10H10N2O2
Formula Weight: 190.2
MOL File: 198821-79-3.mol

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3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE Property

Boiling point:: 318.7±27.0 °C(Predicted)
Density: 1.211±0.06 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2–8 °C
pka: 3.03±0.10(Predicted)
Appearance: Off-white to yellow Solid

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Safety

HS Code: 2934999090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: M266645
Product name: 3-Methoxy-4-(oxazol-5-yl)aniline
Packaging: 20mg
Price: $200
Updated: 2021/12/16

Apolloscientific

Product number: OR927626
Product name: 3-Methoxy-4-(1,3-oxazol-5-yl)aniline
Purity: 98%
Packaging: 1g
Price: $235
Updated: 2021/12/16

Matrix Scientific

Product number: 089547
Product name: 3-Methoxy-4-(1,3-oxazol-5-yl)aniline
Packaging: 5g
Price: $890
Updated: 2021/12/16

ChemScene

Product number: CS-W005501
Product name: 3-Methoxy-4-(oxazol-5-yl)aniline
Purity: 99.80%
Packaging: 25g
Price: $1150
Updated: 2021/12/16

ChemScene

Product number: CS-W005501
Product name: 3-Methoxy-4-(oxazol-5-yl)aniline
Purity: 99.80%
Packaging: 250mg
Price: $24
Updated: 2021/12/16

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3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE Chemical Properties,Usage,Production

Synthesis

198821-78-2

198821-79-3

The general procedure for the synthesis of 3-methoxy-4-(1,3-oxazolyl)aniline from 5-(2-methoxy-4-nitrophenyl)oxazole was as follows: 5-(2-methoxy-4-nitrophenyl)oxazole (10 g, 45.4 mmol) was dissolved in a solvent mixture of tetrahydrofuran (185 ml) and ethanol (37 ml). Palladium-carbon catalyst (Pd/C, 2.0 g, 1.88 mmol) was added to the reaction system under argon protection. After displacing the gas in the reaction system with hydrogen, the reaction mixture was stirred vigorously at room temperature overnight. Upon completion of the reaction, the catalyst was removed by filtration and washed with tetrahydrofuran and ethanol. The filtrate was concentrated to give an oil, which was allowed to stand for several hours and then crystallized. 3-Methoxy-4-(1,3-oxazole)aniline was finally obtained as a yellow solid (8.54 g, 97% yield); mass spectrum (ISN) m/z = 191.08 [(M + H)+].

References

[1] Patent: WO2014/79850, 2014, A1. Location in patent: Page/Page column 53; 54
[2] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 9, p. 1323 - 1326
[3] Bioorganic and Medicinal Chemistry Letters, 2002, vol. 12, # 20, p. 2879 - 2882
[4] Heterocycles, 2006, vol. 68, # 1, p. 167 - 173
[5] Patent: WO2004/214, 2003, A2. Location in patent: Page 42

3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE Suppliers

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View Lastest Price from 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE manufacturers

Career Henan Chemical Co

Product: 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE 198821-79-3
Price: US $1.00/KG
Min. Order: 1KG
Purity: 95%
Supply Ability: 200KG
Release date: 2018-08-19

198821-79-3, 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINERelated Search:

5-(4-ISOCYANATO-2-METHOXYPHENYL)OXAZOLE 5-(2-METHOXY-PHENYL)OXAZOLE MERIMEPODIB 3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE 5-(2-METHOXY-4-NITROPHENYL)OXAZOLE 4-(1,3-OXAZOL-5-YL)ANILINE

3-METHOXY-4-(1,3-OXAZOL-5-YL)ANILINE

BenzenaMine, 3-Methoxy-4-(5-oxazolyl)-

3-Methoxy-4-(oxazol-5-yl)

3-Methoxy-4-(oxazol-5-yl)aniline

3-Methoxy-4-(5-oxazolyl)aniline, 97%

3-Methoxy-4-(5-oxazolyl)benzenamine

5-(4-Amino-2-methoxyphenyl)oxazole

3-Methoxy-4-(5-oxazolyl)aniline

198821-79-3