1-CHLORO-1-NITROPROPANE Property

Boiling point:

142°C (estimate)

Density 

1.2070

vapor pressure 

6 at 25 °C (NIOSH, 1997)

refractive index 

1.4251 (estimate)

solubility 

Soluble in alcohol, ether (Weast, 1986), and many low molecular weight hydrocarbons (pentane, hexane, heptane), and halogenated hydrocarbons such as chloroform, methylene chloride, trichloroethylene.

pka

3.93±0.36(Predicted)

form 

Colorless liquid

color 

Clear, colorless liquid with an unpleasant odor

Water Solubility 

6 mg/L at 20 °C (quoted, Verschueren, 1983)

Henry's Law Constant

0.157 atm?m³/mol at 20 °C (approximate - calculated from water solubility and vapor pressure)

Exposure limits

NIOSH REL: TWA 2 ppm (10 mg/m³), IDLH 100 ppm; OSHA PEL: TWA 20 ppm (100 mg/m³); ACGIH TLV: TWA 2 ppm (adopted).

EPA Substance Registry System

1-Chloro-1-nitropropane (600-25-9)

Safety

Hazard Codes 

Xn

Risk Statements 

20/22

RIDADR 

2810

OEB

B

OEL

TWA: 2 ppm (10 mg/m3)

HazardClass 

6.1(b)

PackingGroup 

III

Hazardous Substances Data

600-25-9(Hazardous Substances Data)

Toxicity

Acute oral LD₅₀ for mice 510 mg/kg (quoted, RTECS, 1985).

IDLA

100 ppm

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H332Harmful if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

1-CHLORO-1-NITROPROPANE Chemical Properties,Usage,Production

Description

Chloronitropropane is a flammable, colorlessliquid with an unpleasant odor that causes tears (lachrimator). Molecular weight =123.5; Specific gravity (H2O:1) =1.2; Boiling point =142.7℃; Vapor pressure =6 mmHg at25℃; Flash point =62℃ (oc). Hazard Identification (basedon NFPA 704 M Rating System): Health (unknown),Flammability 3, Reactivity 2. Slightly soluble in water;solubility =0.6% at 20℃

Chemical Properties

Chloronitroproane is a flammable, colorless liquid with an unpleasant odor that causes tears (lachrymator).

Uses

Fungicide.

Synthesis Reference(s)

The Journal of Organic Chemistry, 42, p. 3764, 1977 DOI: 10.1021/jo00443a034

General Description

Colorless liquid. Unpleasant odor.

Air & Water Reactions

Slightly soluble in water [Lawry's].

Reactivity Profile

1-CHLORO-1-NITROPROPANE is sensitive to heat (may be explosive). 1-CHLORO-1-NITROPROPANE is incompatible with oxidizers. 1-CHLORO-1-NITROPROPANE will attack some forms of plastics, rubber and coatings . Combustible: May produce toxic gases, including nitrogen oxides, hydrogen chloride, and carbon monoxide. Will attack some plastics, rubber, and coatings [USCG, 1999].

Health Hazard

LIQUID: Irritating to skin and eyes. Harmful if swallowed.

Fire Hazard

Combustible: May produce toxic gases, including nitrogen oxides, hydrogen chloride, and carbon monoxide. Will attack some plastics, rubber, and coatings.

Safety Profile

Poison by ingestion, subcutaneous, and possibly other routes. Moderately toxic by inhalation. Causes injury to kidneys, liver, and cardiovascular system. Mutation data reported. Flammable liquid when exposed to heat, flame (sparks), and oxidizers. Moderately explosive when exposed to heat. To fight fire, use alcohol foam, water, CO2, or dry chemical. When heated to decomposition it emits toxic fumes of Cland NOx. See also other chloropropane entries and CHLORIDES.

Potential Exposure

This compound is used in the synthetic rubber industry; as a component in rubber cements; and as a fungicide.

First aid

If this chemical gets into the eyes, remove anycontact lenses at once and irrigate immediately for at least15 min, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts theskin, remove contaminated clothing and wash immediatelywith soap and water. Seek medical attention immediately. Ifthis chemical has been inhaled, remove from exposure,begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR ifheart action has stopped. Transfer promptly to a medicalfacility. When this chemical has been swallowed, get medical attention. Give large quantities of water and inducevomiting. Do not make an unconscious person vomit.Medical observation is recommended for 2448 h afterbreathing overexposure, as pulmonary edema may bedelayed. As first aid for pulmonary edema, a doctor orauthorized paramedic may consider administering a corticosteroid spray.

storage

Color Code—Blue: Health Hazard/Poison: Store ina secure poison location. Prior to working with 1-chloro-1-nitropropane you should be trained on its proper handling andstorage. Before entering confined space where 1-chloro-1-nitropropane may be present, check to make sure that anexplosive concentration does not exist. Store to avoid contactwith strong oxidizers (such as chlorine, bromine, and fluorine), since violent reactions occur. Store in tightly closedcontainers in a cool, well-ventilated area away from heat.Metal containers involving the transfer of this chemicalshould be grounded and bonded. Where possible, automatically pump liquid from drums or other storage containers toprocess containers. Drums must be equipped with self-closingvalves, pressure vacuum bungs, and flame arresters. Use onlynonsparking tools and equipment, especially when openingand closing containers of this chemical. Sources of ignition,such as smoking and open flames, are prohibited where thischemical is used, handled, or stored in a manner that couldcreate a potential fire or explosion hazard.

Shipping

UN2810 Toxic liquids, organic, n.o.s., Hazard Class: 6.1; Labels: 6.1-Poisonous materials, Technical Name Required.

Incompatibilities

May form explosive mixture with air. Strong oxidizers may cause a fire and explosion hazard. May explode when exposed to heat.

Waste Disposal

Incineration (816C, 0.5-second minimum for primary combustion; 1204C, 1.0 second for secondary combustion) after mixing with other fuel. The formation of elemental chlorine may be prevented by injection of steam or using methane as a fuel in the process. Alternatively it may be poured over soda ash, neutralized and flushed into the sewer with large volumes of water.