(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate

Product Name: (R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate
CAS No.: 171230-81-2
Chemical Name: (R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate
Synonyms: (R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate;Methyl (R)-2-[(tert-Butyldimethylsilyl)oxy]propanoate;methyl (2R)-2-[tert-butyl(dimethyl)silyl]oxypropanoate;(R)-2-(tert-Butyl-dimethyl-silanyloxy)-propionic acid methyl ester;Propanoic acid, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester, (2R)-
CBNumber: CB53313490
Molecular Formula: C10H22O3Si
Formula Weight: 218.37
MOL File: 171230-81-2.mol

More

Less

(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate Property

Boiling point:: 211.4±23.0 °C(Predicted)
Density: 0.911±0.06 g/cm3(Predicted)
storage temp.: 2-8°C

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: M343173
Product name: (R)-Methyl2-((tert-butyldimethylsilyl)oxy)propanoate
Packaging: 100mg
Price: $240
Updated: 2021/12/16

AK Scientific

Product number: 0830CS
Product name: (R)-Methyl2-((tert-butyldimethylsilyl)oxy)propanoate
Packaging: 100mg
Price: $103
Updated: 2021/12/16

AK Scientific

Product number: 0830CS
Product name: (R)-Methyl2-((tert-butyldimethylsilyl)oxy)propanoate
Packaging: 5g
Price: $551
Updated: 2021/12/16

Ambeed

Product number: A155826
Product name: (R)-Methyl2-((tert-butyldimethylsilyl)oxy)propanoate
Purity: 97%
Packaging: 100mg
Price: $33
Updated: 2021/12/16

Ambeed

Product number: A155826
Product name: (R)-Methyl2-((tert-butyldimethylsilyl)oxy)propanoate
Purity: 97%
Packaging: 250mg
Price: $59
Updated: 2021/12/16

More

Less

(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate Chemical Properties,Usage,Production

Synthesis

17392-83-5

18162-48-6

171230-81-2

GENERAL STEPS: A mixture of methyl D-lactate (5.1 g, 48.99 mmol), dichloromethane (50 mL), imidazole (5 g, 75 mmol), and tert-butyldimethylchlorosilane (8.85 g, 58.79 mmol) was stirred for 2 hours at room temperature. After completion of the reaction, the mixture was diluted with water and extracted three times with dichloromethane. The organic layers were combined, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by medium pressure liquid chromatography (MPLC), using a petroleum ether solution of 5% ethyl acetate as eluent, to afford methyl (R)-2-((tert-butyldimethylsilyl)oxy)propionate (10.67 g, 100% yield) as a colorless oil.

References

[1] Patent: WO2015/171610, 2015, A2. Location in patent: Paragraph 000507
[2] Chemical Communications, 1997, # 13, p. 1219 - 1220
[3] Patent: WO2016/154533, 2016, A1. Location in patent: Paragraph 00176
[4] Tetrahedron Asymmetry, 2012, vol. 23, # 2, p. 117 - 123
[5] European Journal of Organic Chemistry, 2013, # 3, p. 525 - 532

(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate Suppliers

China 23 India 1 United States 3 Global 27

WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.

Tel: 17702719238 18971495150;
Email: sales@sun-shinechem.com
Country: China
ProdList: 1077
Advantage: 64

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

SanoChem (Chengdu) Tech. Co., Ltd.

Tel: 28-87999436 02887999436
Fax: QQ:2746983436
Email: sales@sano-chem.com
Country: China
ProdList: 3795
Advantage: 55

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Yantai ShengKailun Chemical Technology Co., Ltd.

Tel: 13356901049
Fax: QQ：1025383091
Email: 3119594100@qq.com
Country: China
ProdList: 7964
Advantage: 55

Wuhan Sun-shine Bio-technology Corporation Limited

Tel: +86-027-6552-2453
Email: sales@sun-shinechem.com
Country: China
ProdList: 727
Advantage: 58

Career Henan Chemica Co

Tel: +86-0371-86658258 +8613203830695
Fax: 0371-86658258
Email: laboratory@coreychem.com
Country: China
ProdList: 30229
Advantage: 58

Baimei Jihua (Henan) Pharmaceutical Technology Co., Ltd

Tel: 037188900765 18037465274
Fax: QQ3430974218
Email: enyawanglei@sina.cn
Country: China
ProdList: 13966
Advantage: 58

Shanghai Qiming New Material Co. LTD

Tel: 021-36010885 13661599081
Fax: 021-66167180
Email: sale@qmsilicon.com
Country: China
ProdList: 1474
Advantage: 58

Energy Chemical

Tel: 021-58432009 400-005-6266
Fax: 021-58436166
Email: marketing@energy-chemical.com
Country: China
ProdList: 44918
Advantage: 58

171230-81-2, (R)-methyl 2-(tert-butyldimethylsilyloxy)propanoateRelated Search:

(R)-methyl 2-(tert-butyldimethylsilyloxy)propanoate

Propanoic acid, 2-[[(1,1-dimethylethyl)dimethylsilyl]oxy]-, methyl ester, (2R)-

(R)-2-(tert-Butyl-dimethyl-silanyloxy)-propionic acid methyl ester

methyl (2R)-2-[tert-butyl(dimethyl)silyl]oxypropanoate

Methyl (R)-2-[(tert-Butyldimethylsilyl)oxy]propanoate

171230-81-2