ON-013100

Product Name: ON-013100
CAS No.: 865783-95-5
Chemical Name: ON-013100
Synonyms: ON-013100;UNII-J3I19I491A;ON-013100, 10 mM in DMSO;ON-013100;ON 013100;ON013100;(E)-2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenol;CDK,ON-013100,ON 013100,inhibit,Inhibitor,Cyclin dependent kinase,ON013100;Phenol, 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-
CBNumber: CB53339236
Molecular Formula: C19H22O7S
Formula Weight: 394.44
MOL File: 865783-95-5.mol

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ON-013100 Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-0066132
Product name: ON-013100
Purity: 98.23%
Packaging: 1mg
Price: $90
Updated: 2021/12/16

ChemScene

Product number: CS-0066132
Product name: ON-013100
Purity: 98.23%
Packaging: 5mg
Price: $140
Updated: 2021/12/16

ChemScene

Product number: CS-0066132
Product name: ON-013100
Purity: 98.23%
Packaging: 10mg
Price: $220
Updated: 2021/12/16

ChemScene

Product number: CS-0066132
Product name: ON-013100
Purity: 98.23%
Packaging: 50mg
Price: $620
Updated: 2021/12/16

ChemScene

Product number: CS-0066132
Product name: ON-013100
Purity: 98.23%
Packaging: 100mg
Price: $920
Updated: 2021/12/16

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ON-013100 Chemical Properties,Usage,Production

Uses

ON-013100, an antineoplastic agent, acts a mitotic inhibitor that could inhibit Cyclin D1 expression.

IC 50

Cdk4/cyclin D1

References

[1] Cho SY, et al. Determination of the glucuronide metabolite of ON 013100, a benzylstyrylsulfone antineoplastic drug, in colon cancer cells using LC/MS/MS. J Pharm Biomed Anal. 2013 Mar 5;75:138-44. DOI:10.1016/j.jpba.2012.11.022
[2] Park IW, et al. Evaluation of novel cell cycle inhibitors in mantle cell lymphoma. Oncogene. 2007 Aug 16;26(38):5635-42. DOI:10.1038/sj.onc.1210350
[3] Neel Jasani, et al. Potent anticancer activity of an orally bioavailable small molecule, ON 013100, and its water soluble derivative, briciclib, a clinical-stage eIF4E-targeted agent. AACR 106th Annual Meeting 2015; April 18-22, 2015; Philadelphia, PA.

ON-013100 Preparation Products And Raw materials

Raw materials

Preparation Products

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ON-013100 Suppliers

China 34 United States 3 USA 1 Global 38

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865783-95-5, ON-013100Related Search:

ON-013100

UNII-J3I19I491A

ON-013100;ON 013100;ON013100

Phenol, 2-methoxy-5-[[[(1E)-2-(2,4,6-trimethoxyphenyl)ethenyl]sulfonyl]methyl]-

CDK,ON-013100,ON 013100,inhibit,Inhibitor,Cyclin dependent kinase,ON013100

(E)-2-Methoxy-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)phenol

ON-013100, 10 mM in DMSO

865783-95-5