BAY-Y 3118

Product Name: BAY-Y 3118
CAS No.: 151213-16-0
Chemical Name: BAY-Y 3118
Synonyms: BAY Y 3118,BAYY 3118;3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-
CBNumber: CB53339610
Molecular Formula: C20H21ClFN3O3
Formula Weight: 405.85
MOL File: 151213-16-0.mol

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BAY-Y 3118 Property

Boiling point:: 627.2±55.0 °C(Predicted)
Density: 1.486±0.06 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
form: Solid
pka: 6.40±0.50(Predicted)
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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BAY-Y 3118 Chemical Properties,Usage,Production

Uses

BAY-Y 3118 is a new chlorofluoroquinolone with antimicrobial activity.

in vivo

Immunocompetent mice are rapidly cured by treatment with 4 mg every 12 h. Concomitantly, the levels of interleukin 6 and gamma interferon in mouse sera decline rapidly. In immunocompetent mice, treatment with 2 mg of BAY-Y 3118 every 12 h results in a greater initial reduction in the listerial counts in the organs than treatment with 2 mg of ampicillin every 12 h. BAY-Y 3118 completely eliminates L. monocytogenes from the livers and spleens of chronically infected nude mice^[3].

References

[1] Fass RJ, et al. In vitro activity of Bay y 3118, a new quinolone. Antimicrob Agents Chemother. 1993 Nov;37(11):2348-57. DOI:10.1128/AAC.37.11.2348
[2] García I, et al. Intracellular penetration and activity of BAY Y 3118 in human polymorphonuclear leukocytes. Antimicrob Agents Chemother. 1994 Oct;38(10):2426-9. DOI:10.1128/AAC.38.10.2426
[3] Nichterlein T, et al. Bay Y 3118, a new quinolone derivative, rapidly eradicates Listeria monocytogenes from infected mice and L929 cells. Antimicrob Agents Chemother. 1994 Jul;38(7):1501-6. DOI:10.1128/AAC.38.7.1501

BAY-Y 3118 Preparation Products And Raw materials

Raw materials

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BAY-Y 3118 Suppliers

China 9 United States 5 USA 1 Global 15

MedChemexpress LLC

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151213-16-0, BAY-Y 3118Related Search:

BAY Y 3118,BAYY 3118

3-Quinolinecarboxylic acid, 8-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-

151213-16-0