Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-

Product Name: Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-
CAS No.: 142648-47-3
Chemical Name: Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-
Synonyms: Anti-Heart Failure Agent 1;AntiHeart Failure Agent 1,Anti Heart Failure Agent 1;Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-
CBNumber: CB53339625
Molecular Formula: C11H11FN2O3S
Formula Weight: 270.2800432
MOL File: 142648-47-3.mol

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Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- Property

Boiling point:: 413.5±55.0 °C(Predicted)
Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 6.32±0.69(Predicted)

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Hazard and Precautionary Statements (GHS)

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Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- Chemical Properties,Usage,Production

Uses

Anti-Heart Failure Agent 1 an orally available compound suitable for the treatment of heart failure without inducing nausea, vomiting and restlessness.

in vivo

15 mg/kg of compound produces 60% increase in left ventricular contractility in anaesthetized cat. An oral dose of compound (25 mg/kg) could produce marked increases in left ventricular contractility (45%) in conscious dog^[1].

References

[1] EP0482717A1

Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy- Suppliers

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142648-47-3, Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-Related Search:

Benzo[b]thiophene-2-carboximidamide, 4-fluoro-N-hydroxy-5,6-dimethoxy-

Anti-Heart Failure Agent 1

AntiHeart Failure Agent 1,Anti Heart Failure Agent 1

142648-47-3