ChemicalBook > CAS DataBase List > Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]-
Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]-
- Product Name
- Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]-
- CAS No.
- 133012-00-7
- Chemical Name
- Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]-
- Synonyms
- LTB4-IN-1;LTB4-IN-1, 10 mM in DMSO;Anti-inflammatory agent 2;Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]-
- CBNumber
- CB53339645
- Molecular Formula
- C26H30N2O4S
- Formula Weight
- 466.6
- MOL File
- 133012-00-7.mol
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Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Property
- Density
- 1.243±0.06 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- Soluble in DMSO
- pka
- 4.22±0.40(Predicted)
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Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Chemical Properties,Usage,Production
Uses
LTB4-IN-1 (Compound 6) is a leukotriene synthesis (LTB4) inhibitor with an IC50 of 70 nM[1].
IC 50
LTB4: 70 nM (IC50)
References
[1] Hatzelmann A, et al. Inversely-correlated inhibition of human 5-lipoxygenase activity by BAY X1005 and other quinoline derivatives in intact cells and a cell-free system--implications for the function of 5-lipoxygenase activating protein. Biochem Pharmacol. 1994 Jun 15;47(12):2259-68. DOI:10.1016/0006-2952(94)90264-x
Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Preparation Products And Raw materials
Raw materials
Preparation Products
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Cycloheptaneacetamide, N-(methylsulfonyl)-α-[4-(2-quinolinylmethoxy)phenyl]- Suppliers
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