Eribulin intermediate

Product Name: Eribulin intermediate
CAS No.: 253128-15-3
Chemical Name: Eribulin intermediate
Synonyms: Eribu;ER-076349;Eribulin N-3;Eribulin Impurity 12;Azerbrin Impurity 12;Eribulin Mesylate N-3;Eribulin mesylate Impurity 9;(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R...;Eribulin Impurity 12Q: What is Eribulin Impurity 12 Q: What is the CAS Number of Eribulin Impurity 12;11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-
CBNumber: CB53339872
Molecular Formula: C40H58O12
Formula Weight: 730.88
MOL File: 253128-15-3.mol

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Eribulin intermediate Property

form: Solid
color: White to off-white
InChIKey: NKVBBIDGGDRJNL-LUFZHUSSNA-N

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Hazard and Precautionary Statements (GHS)

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Eribulin intermediate Chemical Properties,Usage,Production

Uses

ER-076349 (Eribulin intermediate) is an inhibitor of tubulin polymerization, induces G2-M cell cycle arrest, and disrupts mitotic spindles. ER-076349 inhibits cancer cell growth, and inhibits tumor growth in several human tumor xenografts. ER-076349 is an analog of Halichondrin B[1].

References

[1] Towle MJ, et al. In vitro and in vivo anticancer activities of synthetic macrocyclic ketone analogues of halichondrin B. Cancer Res. 2001 Feb 1;61(3):1013-21. PMID:11221827

Eribulin intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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Eribulin intermediate Suppliers

China 27 India 2 Global 29

Lianyungang TengFa Biological Technology Co. Ltd

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253128-15-3, Eribulin intermediateRelated Search:

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Eribulin N-3

Eribulin Impurity 12

11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one, 2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-, (2R,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-

ER-076349

(1S,3S,6S,9S,12S,14R,16R,18S,20R,21R,22S,26R,29S,31R,32S,35R...

Eribulin Impurity 12Q: What is Eribulin Impurity 12 Q: What is the CAS Number of Eribulin Impurity 12

Eribulin Mesylate N-3

Eribu

11,15:18,21:24,28-Triepoxy-7,9-ethano-12,15-methano-9H,15H-furo[3,2-i]furo[2',3':5,6]pyrano[4,3-b][1,4]dioxacyclopentacosin-5(4H)-one,2-[(2S)-2,3-dihydroxypropyl]hexacosahydro-3-methoxy-26-methyl-20,27-bis(methylene)-,(2ChemicalbookR,3R,3aS,7R,8aS,9S,10aR,11S,12R,13aR,13bS,15S,18S,21S,24S,26R,28R,29aS)-

Eribulin mesylate Impurity 9

Azerbrin Impurity 12

253128-15-3

C40H58O12