ChemicalBook > CAS DataBase List > BocNH-PEG7-OH

BocNH-PEG7-OH

Product Name
BocNH-PEG7-OH
CAS No.
1292268-13-3
Chemical Name
BocNH-PEG7-OH
Synonyms
tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate;NHBoc-PEG7-OH;BocNH-PEG7-OH;BocNH-PEG7-alcohol;N-Boc-PEG7-alcohol N-Boc-;t-boc-N-amido-PEG7-alcohol;20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol;t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate;5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester;BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
CBNumber
CB53340579
Molecular Formula
C19H39NO9
Formula Weight
425.51
MOL File
1292268-13-3.mol
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BocNH-PEG7-OH Property

Boiling point:
521.1±50.0 °C(Predicted)
Density 
1.090±0.06 g/cm3(Predicted)
solubility 
Soluble in Water, DMSO, DCM, DMF
pka
12.23±0.46(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23546
Product name
N-Boc-PEG7-alcohol
Purity
98%
Packaging
500mg
Price
$280
Updated
2021/12/16
Activate Scientific
Product number
AS104083
Product name
BocNH-PEG7-OH
Purity
95+%
Packaging
1g
Price
$615
Updated
2021/12/16
purepeg
Product number
432407
Product name
BocNH-PEG7-OH
Purity
min.95%
Packaging
1g
Price
$350
Updated
2021/12/16
purepeg
Product number
432407
Product name
BocNH-PEG7-OH
Purity
min.95%
Packaging
250mg
Price
$185
Updated
2021/12/16
Acrotein
Product number
B-0973
Product name
BocNH-PEG7-OH
Purity
97%
Packaging
0.25g
Price
$192.5
Updated
2021/12/16
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BocNH-PEG7-OH Chemical Properties,Usage,Production

Description

N-Boc-PEG7-alcohol is a PEG linker containing a hydroxyl group and Boc-protected amino group. The hydrophilic PEG spacer increases solubility in aqueous media. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. The Boc group can be deprotected under mild acidic conditions to form the free amine.

Biological Activity

N-Boc-PEG7-alcohol is a PROTAC bridge that belongs to the PEG class and the Alkyl/ether class. It can be used to synthesize a series of PROTAC molecules. Also it is a cleavable ADC linker for the synthesis of antibody drug conjugates (ADCs).

in vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

target

Cleavable

PEGs

Alkyl/ether

BocNH-PEG7-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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BocNH-PEG7-OH Suppliers

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View Lastest Price from BocNH-PEG7-OH manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
NHBoc-PEG7-OH 1292268-13-3
Price
US $0.00/g
Min. Order
5g
Purity
>98.00%
Supply Ability
5g
Release date
2024-03-25

1292268-13-3, BocNH-PEG7-OHRelated Search:


  • BocNH-PEG7-OH
  • NHBoc-PEG7-OH
  • 5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
  • t-boc-N-amido-PEG7-alcohol
  • t-butyl20-hydroxy-3,6,9,12,15,18-hexaoxaicosylcarbamate
  • tert-Butyl (20-hydroxy-3,6,9,12,15,18-hexaoxaicosyl)carbamate
  • 20-(Boc-amino)-3,6,9,12,15,18-hexaoxa-1-icosanol
  • BocNH-PEG7-OH/5,8,11,14,17,20-Hexaoxa-2-azadocosanoic acid, 22-hydroxy-, 1,1-dimethylethyl ester
  • BocNH-PEG7-alcohol
  • N-Boc-PEG7-alcohol N-Boc-
  • tert-butyl N-[2-[2-[2-[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]carbamate
  • 1292268-13-3
  • C19H39NO9
  • peg