ChemicalBook > CAS DataBase List > Sarolaner

Sarolaner

Product Name: Sarolaner
CAS No.: 1398609-39-6
Chemical Name: Sarolaner
Synonyms: Saiolana;Saoranna;PF6450567;Sarolaner;Sharolana;PF 6450567;PF 6450567;PF6450567;Sarolaner(PF-6450567);Sarolaner, 10 mM in DMSO;Sarolaner (Synonyms: PF-6450567)
CBNumber: CB53344764
Molecular Formula: C23H18Cl2F4N2O5S
Formula Weight: 581.36
MOL File: 1398609-39-6.mol

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Sarolaner Property

Boiling point:: 722.7±70.0 °C(Predicted)
Density: 1.65±0.1 g/cm3(Predicted)
storage temp.: Store at 4°C, sealed storage, away from moisture
solubility: DMF: Slightly soluble; DMSO: Slightly soluble; Ethanol: Slightly soluble
form: A solid
pka: -0.93±0.20(Predicted)
color: White to off-white
InChIKey: FLEFKKUZMDEUIP-QFIPXVFZSA-N
SMILES: C(=O)(N1CC2(C3=C(C=C(C4C[C@](C5=CC(Cl)=C(F)C(Cl)=C5)(C(F)(F)F)ON=4)C=C3)CO2)C1)CS(C)(=O)=O

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P273Avoid release to the environment.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P391Collect spillage. Hazardous to the aquatic environment

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: S141670
Product name: Sarolaner
Packaging: 1mg
Price: $415
Updated: 2021/12/16

ChemScene

Product number: CS-0012328
Product name: Sarolaner
Purity: 99.47%
Packaging: 50mg
Price: $850
Updated: 2021/12/16

ChemScene

Product number: CS-0012328
Product name: Sarolaner
Purity: 99.47%
Packaging: 100mg
Price: $1500
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573185
Product name: Sarolaner(PF-6450567)
Purity: >98%
Packaging: 100mg
Price: $1654.1
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb573185
Product name: Sarolaner(PF-6450567)
Purity: >98%
Packaging: 250mg
Price: $3136.5
Updated: 2021/12/16

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Sarolaner Chemical Properties,Usage,Production

Uses

Sarolaner is used in the making of formulations for the control of ticks in cats, and flea infestations in dogs. A parasiiticide.

in vivo

Sarolaner (2.5 mg/kg; p.o. once) shows 100% efficacious against R. sanguineus and D. reticulatus^[1]. Sarolaner (1.25- 5 mg/kg; p.o. once) effectively against I. ricinus^[1].

Animal Model:	Dog infested with R. sanguineus and D. reticulatus^[1]
Dosage:	2.5 mg/kg
Administration:	Oral gavage; 2.5 mg/kg once
Result:	Exibited 100% efficacy against R. sanguineus at 48 hours after treatment and also exhibited 98.0% efficacy againstD. reticulatus.

Animal Model:	Dog infested with I. ricinus^[1]
Dosage:	1.25, 2.5 and 5 mg/kg
Administration:	Oral gavage; 1.25, 2.5 and 5 mg/kg once
Result:	Exibited 100% efficacy against I. ricinus at all doses until 7 days, and provided over 99.3% reduction against subsequent re-infestations until 57 days at dose of 5.0 and 2.5 mg/kg.

Sarolaner Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Sarolaner manufacturers

Wuhan Haorong Biotechnology Co.,Ltd

Product: Sarolaner 1398609-39-6
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10000
Release date: 2025-07-08

Wuhan Biocar Pharmacy CO.,Ltd.

Product: *Sarolaner 1398609-39-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 0.99
Supply Ability: 2500kg
Release date: 2025-03-05

Shandong Xuhuang New material CoLTD

Product: Sarolaner 1398609-39-6
Price: US $62.00/KG
Min. Order: 1KG
Purity: 99.99%
Supply Ability: 10T
Release date: 2025-02-25

1398609-39-6, SarolanerRelated Search:

Sarolaner

1-[6-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone

PF 6450567;PF6450567

PF6450567

PF 6450567

Sarolaner(PF-6450567)

(S)-1-(5'-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone

Ethanone, 1-[5'-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-yl]-2-(methylsulfonyl)-

dog,Sarolaner,Parasite,PF 6450567,flea,Inhibitor,oral,inhibit,isoxazoline,tick,PF6450567

(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one

Sarolaner, 10 mM in DMSO

Sarolaner (Synonyms: PF-6450567)

Saiolana

Saoranna

Sharolana

(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one

Sarolaner 100 μg/mL in Acetonitrile

1398609-39-6

C23H18Cl2F4N2O5S