PC-Biotin-PEG4-NHS carbonate
- Product Name
- PC-Biotin-PEG4-NHS carbonate
- CAS No.
- 2055198-03-1
- Chemical Name
- PC-Biotin-PEG4-NHS carbonate
- Synonyms
- PC-Biotin-PEG4-NHS carbonate;1-(5-(3,19-Dioxo-23-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)-6,9,12,15-tetraoxa-2,18-diazatricosyl)-2-nitrophenyl)ethyl (2,5-dioxopyrrolidin-1-yl) carbonate;Carbonic acid, 2,5-dioxo-1-pyrrolidinyl 1-[5-[23-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-3,19-dioxo-6,9,12,15-tetraoxa-2,18-diazatricos-1-yl]-2-nitrophenyl]ethyl ester
- CBNumber
- CB53363985
- Molecular Formula
- C35H50N6O14S
- Formula Weight
- 810.87
- MOL File
- 2055198-03-1.mol
PC-Biotin-PEG4-NHS carbonate Property
- Density
- 1.39±0.1 g/cm3(Predicted)
- storage temp.
- Storage temp. -20°C
- solubility
- Soluble in DMSO, DCM, DMF
- pka
- 13.90±0.40(Predicted)
- form
- Solid
- color
- White to off-white
N-Bromosuccinimide Price
- Product number
- BP-23108
- Product name
- PC-Biotin-PEG4-NHScarbonate
- Packaging
- 5mg
- Price
- $670
- Updated
- 2021/12/16
PC-Biotin-PEG4-NHS carbonate Chemical Properties,Usage,Production
Description
PC-Biotin-PEG4-NHS carbonate is a unique amine reactive, photocleavable biotin reagent that is useful for introducing a biotin moiety to amine-containing biomolecules. The NHS carbonate portion of this compound reacts specifically with primary amine groups on the target molecule(s) to form a carbamate linkage. Captured biomolecules can be efficiently photoreleased using an inexpensive, near-UV, low intensity lamp (e.g. 365 nm lamp at 1-5 mW/cm2).
Uses
PC-Biotin-PEG4-NHS carbonate is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
PEGs; Alkyl/ether
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
PC-Biotin-PEG4-NHS carbonate Preparation Products And Raw materials
Raw materials
Preparation Products
PC-Biotin-PEG4-NHS carbonate Suppliers
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View Lastest Price from PC-Biotin-PEG4-NHS carbonate manufacturers
- Product
- PC-Biotin-PEG4-NHS carbonate 2055198-03-1
- Price
- US $0.00/mg
- Min. Order
- 25mg
- Purity
- >98.00%
- Supply Ability
- 25mg
- Release date
- 2024-03-30