ChemicalBook > CAS DataBase List > N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)

N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)

Product Name
N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)
CAS No.
653600-56-7
Chemical Name
N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)
Synonyms
Ac4GaINAz;Ac4GalNAz;GalNAz tetraacetate;N-Azidoacetylgalactosamine, Acylated;N-Azidoacetylgalactosamine-tetraacylated;N-Azidoacetylgalactosamine-tetraacylated;1,3,4,6-Tetra-O-acetyl-N-azidoacetylgalactosamine;N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz);Ac4GalNAz,PROTAC Linkers,inhibit,Ac-4GalNAz,Inhibitor;N-N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz)
CBNumber
CB53364124
Molecular Formula
C16H22N4O10
Formula Weight
430.37
MOL File
653600-56-7.mol
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N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) Property

storage temp. 
-20°C
solubility 
DMSO, DMF, DCM, THF, Chloroform
form 
powder or crystals
color 
White to off-white
Appearance
white crystals
InChIKey
HGMISDAXLUIXKM-FECVBEAVNA-N
SMILES
O([C@H]1[C@H]([C@@H](COC(=O)C)OC(OC(=O)C)[C@@H]1NC(=O)CN=[N+]=[N-])OC(=O)C)C(=O)C |&1:1,2,3,15,r|
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
900915
Product name
N-Azidoacetylgalactosamine-tetraacylated
Packaging
50MG
Price
$403
Updated
2025/07/31
Biosynth Carbosynth
Product number
MA46005
Product name
1,3,4,6-Tetra-O-acetyl-N-azidoacetylgalactosamine
Packaging
100mg
Price
$550
Updated
2021/12/16
BroadPharm
Product number
BP-24306
Product name
N-N-azidoacetylgalactosamine-tetraacylated(Ac4GalNAz)
Purity
95%
Packaging
100mg
Price
$595
Updated
2021/12/16
Chem-Impex
Product number
35139
Product name
N-azidoacetylgalactosamine-tetraacylated(Ac4GalNAz),≥90%
Purity
≥90%
Packaging
100MG
Price
$780.42
Updated
2021/12/16
AK Scientific
Product number
7080DU
Product name
Ac4GalNAz
Packaging
100mg
Price
$792
Updated
2021/12/16
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N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) Chemical Properties,Usage,Production

Description

The unnatural azido-containing monosaccharide building block. The azide moiety can be used for modification though chemoselective ligation chemistries including CuAAC, Cu-free click reaction or Staudinger ligation. The acetyl groups increase solubility in many solvents and make handling of this reagent easier.

Uses

N-Azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) provides the first part of a simple and robust two-step technique that helps identify and characterize cell surface sialic acid-containing glycoproteins. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

Application

N-Azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) provides the first part of a simple and robust two-step technique that helps identify and characterize cell surface sialic acid-containing glycoproteins. The azide-modified protein can be detected by reaction with alkynes. For example alkynes labeled with a fluorescent probe or a biotin can be used. The acetyl groups increase cell permeability and allow the unnatural sugars to easily pass through the cell membrane. Carboxyesterases remove the acetyl groups once the monosaccharide is in the cell.

reaction suitability

reaction type: click chemistry

IC 50

Alkyl-Chain

N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) Suppliers

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View Lastest Price from N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) 653600-56-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-09-27
Xian confluore Biological Technology Co., Ltd.
Product
Ac4GalNAz 653600-56-7
Price
US $0.00/mg
Min. Order
50mg
Purity
>95.00%
Supply Ability
50mg
Release date
2024-03-30
GlycoPharm.LLC
Product
Ac4GalNAz 653600-56-7
Price
US $0.00/mg
Min. Order
10mg
Purity
97%HPLC
Supply Ability
MG-KG
Release date
2020-03-17

653600-56-7, N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)Related Search:


  • N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz)
  • N-Azidoacetylgalactosamine-tetraacylated
  • Ac4GalNAz
  • N-Azidoacetylgalactosamine, Acylated
  • 2-[(2-Azidoacetyl) amino] -2-deoxy-1,3,4,6- tetra-O-acetyl-D-galac- topyranose
  • 1,3,4,6-Tetra-O-acetyl-N-azidoacetylgalactosamine
  • 1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos
  • N-N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz)
  • N-azidoacetylgalactosamine-tetraacylated (Ac4GaINAz) USP/EP/BP
  • Ac4GalNAz,PROTAC Linkers,inhibit,Ac-4GalNAz,Inhibitor
  • Ac4GaINAz
  • GalNAz tetraacetate
  • (2R,3R,4R,5R)-3,4,6-triacetyloxy-5-[(2-azidoacetyl)amino]oxan-2-yl]methyl acetate
  • 2-[(Azidoacetyl)amino]-2-deoxy-D-glactopyranose 1,3,4,6-tetraacetate
  • (3R,4R,5R,6R)-6-(acetoxymethyl)-3-(2-azidoacetamido)tetrahydro-2H-pyran-2,4,5-triyl triacetate
  • D-Galactopyranose, 2-[(2-azidoacetyl)amino]-2-deoxy-, 1,3,4,6-tetraacetate
  • 1,3,4,6-Tetra-O-acetyl-N-azidoacetylgalactosamine/Ac4GalNAz
  • <i>N</i>-Azidoacetylgalactosamine-tetraacylated
  • N-azidoacetylgalactosamine-tetraacylated (Ac4GalNAz) (CCT-1086)
  • 1,3,4,6-Tetra-O-acetyl-2-[(azidoacetyl)amino]-2-deoxy-β-D-galactopyranos
  • (3R,4R,5R,6R)-6-(Acetoxymethyl)-3-(2-azidoacetcarboxcarboxcarboxamido)-tetrahydro-2H-pyran-2,4,5-triyl triacetate
  • 653600-56-7