1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine

Product Name: 1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine
CAS No.: 167695-87-6
Chemical Name: 1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine
Synonyms: N4Py;N 4 Py;N-4-Py;1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine;2-Pyridinemethanamine, α-2-pyridinyl-N,N-bis(2-pyridinylmethyl)-
CBNumber: CB53368041
Molecular Formula: C23H21N5
Formula Weight: 367.45
MOL File: 167695-87-6.mol

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1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine Property

Boiling point:: 490.6±40.0 °C(Predicted)
Density: 1.208±0.06 g/cm3(Predicted)
pka: 4.61±0.12(Predicted)

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Hazard and Precautionary Statements (GHS)

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1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine Chemical Properties,Usage,Production

Uses

N4Py is a pentadentate ligand, that forms a stable complex with metal ions, such as iron, platinum, and copper. N4py mimics the metal binding domains of iron-dependent antibiotics like Bleomycin(HY-17565), forms the DNA-cleaving FeII-N4Py complexes, generates reactive oxygen species (ROS), and causes oxidative damage in cells. N4py can be used in cancer research[1].

References

[1] Geersing A, et al., Importance of Metal-Ion Exchange for the Biological Activity of Coordination Complexes of the Biomimetic Ligand N4Py. Inorg Chem. 2018 Jul 2;57(13):7748-7756. DOI:10.1021/acs.inorgchem.8b00714

1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine Preparation Products And Raw materials

Raw materials

Preparation Products

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1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine Suppliers

CHINA 5 United States 2 Global 7

Zhengzhou Ruke Biological Co., Ltd.

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167695-87-6, 1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamineRelated Search:

1,1-di(pyridin-2-yl)-N,N-bis(pyridin-2-ylmethyl)methanamine

2-Pyridinemethanamine, α-2-pyridinyl-N,N-bis(2-pyridinylmethyl)-

N 4 Py

N4Py

N-4-Py

167695-87-6