[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate

Product Name: [2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate
CAS No.: 491611-43-9
Chemical Name: [2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate
Synonyms: MRS2298, CID:10432920;[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate;1,3-Propanediol, 2-[[2-chloro-6-(methylamino)-9H-purin-9-yl]methyl]-, 1,3-bis(dihydrogen phosphate)
CBNumber: CB53369972
Molecular Formula: C10H16ClN5O8P2
Formula Weight: 431.66
MOL File: 491611-43-9.mol

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[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate Property

Boiling point:: 735.8±70.0 °C(Predicted)
Density: 2.03±0.1 g/cm3(Predicted)
pka: 1.55±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate Chemical Properties,Usage,Production

Description

MRS2298 is a potent antagonists of the P2Y 1 receptor, which has antiaggregatory activity in human platelets.

Uses

MRS2298? is a potent acyclic P2Y1 receptor antagonist with a Ki of 29.6 nM. MRS2298 inhibits the ADP-induced aggregation of human platelets with an IC50 of 62.8 nM. MRS2298 inhibits Ca2+ rise in platelets with an IC50 of 810 nM[1].

References

[1] Marco Cattaneo, et al. Antiaggregatory activity in human platelets of potent antagonists of the P2Y 1 receptor. Biochem Pharmacol. 2004 Nov 15;68(10):1995-2002. DOI:10.1016/j.bcp.2004.06.026

[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate Suppliers

China 4 United States 2 Global 6

Jinan Yaoyan Pharmaceutical Co., Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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JinOu Biomedical (Nanjing) Co., Ltd.

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TargetMol Chemicals Inc.

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TargetMol Chemicals Inc.

Tel: +17819995354
Email: marketing@targetmol.com
Country: United States
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491611-43-9, [2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphateRelated Search:

MRS2298, CID:10432920

[2-[(2-chloro-6-methylaminopurin-9-yl)methyl]-3-phosphonooxypropyl] dihydrogen phosphate

1,3-Propanediol, 2-[[2-chloro-6-(methylamino)-9H-purin-9-yl]methyl]-, 1,3-bis(dihydrogen phosphate)

491611-43-9