rolapitant intermediate

Product Name: rolapitant intermediate
CAS No.: 873947-10-5
Chemical Name: rolapitant intermediate
Synonyms: NK-1 Antagonist 1;NK 1 Antagonist 1,NK1 Antagonist 1;3-Piperidinecarbonitrile, 6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl)-6-phenyl-, (3S,6S)-
CBNumber: CB53373014
Molecular Formula: C25H23F6N5O2
Formula Weight: 539.47
MOL File: 873947-10-5.mol

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rolapitant intermediate Property

storage temp.: Store at -20°C
solubility: Soluble in DMSO

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Hazard and Precautionary Statements (GHS)

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rolapitant intermediate Chemical Properties,Usage,Production

Uses

SCH 900978 (NK-1 Antagonist 1) is an antagonist of NK-1 receptor, used in the research of NK-1 related diseases and conditions such as cough, overactive bladder, alcohol dependency and depression[1].

References

[1] Jane H. Hsiao, et al. Heteroaryl carbonitriles for the treatment of disease. WO2017011445A1.

rolapitant intermediate Preparation Products And Raw materials

Raw materials

Preparation Products

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rolapitant intermediate Suppliers

China 7 United States 1 Global 8

Jinan Yaoyan Pharmaceutical Co., Ltd.

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Fan De(Beijing) Biotechnology Co., Ltd.

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Nanjing Meihao Pharmaceutical Technology Co., Ltd.

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TargetMol Chemicals Inc.

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Beijing Jin Ming Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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Biosynth Biological Technology (Suzhou) Co Ltd

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Adooq Bioscience LLC

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873947-10-5, rolapitant intermediateRelated Search:

NK-1 Antagonist 1

3-Piperidinecarbonitrile, 6-[[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]methyl]-3-(1,5-dihydro-5-oxo-4H-1,2,4-triazol-4-yl)-6-phenyl-, (3S,6S)-

NK 1 Antagonist 1,NK1 Antagonist 1

873947-10-5

C25H23F6N5O2