N-(Azido-PEG2)-N-Fluorescein-PEG3-acid

Product Name: N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
CAS No.: 2086689-04-3
Chemical Name: N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
Synonyms: PUN 89043;PROTAC Linker;N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
CBNumber: CB53373685
Molecular Formula: C36H41N5O12S
Formula Weight: 767.81
MOL File: 2086689-04-3.mol

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

BroadPharm

Product number: BP-23521
Product name: N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
Purity: 98%
Packaging: 1mg
Price: $190
Updated: 2021/12/16

BroadPharm

Product number: BP-23521
Product name: N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
Purity: 98%
Packaging: 2mg
Price: $330
Updated: 2021/12/16

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N-(Azido-PEG2)-N-Fluorescein-PEG3-acid Chemical Properties,Usage,Production

Description

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a fluorescein dye linker containing a terminal azide group and a terminal carboxylic acid. The azide group enables PEGylation via Click Chemistry. The terminal carboxylic acid can react with primary amino groups in the presence of activators (e.g. EDC, or HATU) to form a stable amide bond.

Uses

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid Preparation Products And Raw materials

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Preparation Products

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N-(Azido-PEG2)-N-Fluorescein-PEG3-acid Suppliers

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View Lastest Price from N-(Azido-PEG2)-N-Fluorescein-PEG3-acid manufacturers

Xian confluore Biological Technology Co., Ltd.

Product: N-(Azido-PEG2)-N-Fluorescein-PEG3-acid 2086689-04-3
Price: US $0.00/mg
Min. Order: 5mg
Purity: >95.00%
Supply Ability: 5mg
Release date: 2024-03-28

2086689-04-3, N-(Azido-PEG2)-N-Fluorescein-PEG3-acidRelated Search:

N-(Azido-PEG2)-N-Fluorescein-PEG3-acid

PUN 89043

PROTAC Linker

2086689-04-3