N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- Product Name
- N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- CAS No.
- 2100306-63-4
- Chemical Name
- N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- Synonyms
- N-(Boc-PEG1)-N-bis(PEG2-propargyl);5,11,14-Trioxa-2,8-diazaheptadec-16-ynoic acid, 8-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
- CBNumber
- CB53373706
- Molecular Formula
- C23H40N2O7
- Formula Weight
- 456.57
- MOL File
- 2100306-63-4.mol
N-(Boc-PEG1)-N-bis(PEG2-propargyl) Property
- Boiling point:
- 535.4±50.0 °C(Predicted)
- Density
- 1.068±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- form
- Viscous Liquid
- pka
- 12.26±0.46(Predicted)
- color
- Colorless to light yellow
N-Bromosuccinimide Price
- Product number
- BP-23563
- Product name
- N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- Purity
- 98%
- Packaging
- 100mg
- Price
- $320
- Updated
- 2021/12/16
- Product number
- BP-23563
- Product name
- N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- Purity
- 98%
- Packaging
- 250mg
- Price
- $650
- Updated
- 2021/12/16
- Product number
- BP-23563
- Product name
- N-(Boc-PEG1)-N-bis(PEG2-propargyl)
- Purity
- 98%
- Packaging
- 500mg
- Price
- $980
- Updated
- 2021/12/16
N-(Boc-PEG1)-N-bis(PEG2-propargyl) Chemical Properties,Usage,Production
Description
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry branched linker. The propargyl groups can react with azide-bearing molecule via copper catalyzed Click Chemistry . The Boc group can be deprotected under acidic conditions to release amine group.
Uses
N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
N-(Boc-PEG1)-N-bis(PEG2-propargyl) Preparation Products And Raw materials
Raw materials
Preparation Products
N-(Boc-PEG1)-N-bis(PEG2-propargyl) Suppliers
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View Lastest Price from N-(Boc-PEG1)-N-bis(PEG2-propargyl) manufacturers
- Product
- N-(Boc-PEG1)-N-bis(PEG2-propargyl) 2100306-63-4
- Price
- US $0.00/mg
- Min. Order
- 250mg
- Purity
- >95.00%
- Supply Ability
- 250mg
- Release date
- 2024-03-28