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N-(Boc-PEG1)-N-bis(PEG2-propargyl)

Product Name
N-(Boc-PEG1)-N-bis(PEG2-propargyl)
CAS No.
2100306-63-4
Chemical Name
N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Synonyms
N-(Boc-PEG1)-N-bis(PEG2-propargyl);5,11,14-Trioxa-2,8-diazaheptadec-16-ynoic acid, 8-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
CBNumber
CB53373706
Molecular Formula
C23H40N2O7
Formula Weight
456.57
MOL File
2100306-63-4.mol
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N-(Boc-PEG1)-N-bis(PEG2-propargyl) Property

Boiling point:
535.4±50.0 °C(Predicted)
Density 
1.068±0.06 g/cm3(Predicted)
storage temp. 
2-8°C, protect from light
form 
Viscous Liquid
pka
12.26±0.46(Predicted)
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P330Rinse mouth.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

BroadPharm
Product number
BP-23563
Product name
N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Purity
98%
Packaging
100mg
Price
$320
Updated
2021/12/16
BroadPharm
Product number
BP-23563
Product name
N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Purity
98%
Packaging
250mg
Price
$650
Updated
2021/12/16
BroadPharm
Product number
BP-23563
Product name
N-(Boc-PEG1)-N-bis(PEG2-propargyl)
Purity
98%
Packaging
500mg
Price
$980
Updated
2021/12/16
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N-(Boc-PEG1)-N-bis(PEG2-propargyl) Chemical Properties,Usage,Production

Description

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry branched linker. The propargyl groups can react with azide-bearing molecule via copper catalyzed Click Chemistry . The Boc group can be deprotected under acidic conditions to release amine group.

Uses

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

IC 50

PEGs

References

[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

N-(Boc-PEG1)-N-bis(PEG2-propargyl) Preparation Products And Raw materials

Raw materials

Preparation Products

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N-(Boc-PEG1)-N-bis(PEG2-propargyl) Suppliers

Bide Pharmatech Ltd.
Tel
400-400-164-7117 18317119277
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
40000
Advantage
60
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
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58
Xi'an Confluore Biological Technology Co., Ltd.
Tel
+86-156-80926068 +86-15680926068
Email
1924344760@qq.com
Country
China
ProdList
4952
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58
TargetMol Chemicals Inc.
Tel
+1-781-999-5354; +17819995354
Email
marketing@targetmol.com
Country
United States
ProdList
32469
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58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
400-8210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
54995
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58
Guangzhou Hongyuan Chemical Co.,Ltd
Tel
15817493340
Email
981810490@qq.com
Country
China
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1566
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58
Zhengzhou Akem Chemical Co., Ltd
Tel
13303867194
Email
3001317055@qq.com
Country
China
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9779
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58
Beijing Jin Ming Biotechnology Co., Ltd.
Tel
010-60605840 15801484223;
Email
psaitong@jm-bio.com
Country
China
ProdList
29757
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58
Shanghai Huici Pharmaceutical Technology Co., LTD
Tel
133-31922809 19372841038
Email
lixing@pharmahuici.com
Country
China
ProdList
842
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58
Zhejiang Rui 'ao Biological Technology Co.,LTD.
Tel
+86-573-82087565 15757883359
Email
yan@ruiaochem.cn
Country
China
ProdList
640
Advantage
58
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View Lastest Price from N-(Boc-PEG1)-N-bis(PEG2-propargyl) manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
N-(Boc-PEG1)-N-bis(PEG2-propargyl) 2100306-63-4
Price
US $0.00/mg
Min. Order
250mg
Purity
>95.00%
Supply Ability
250mg
Release date
2024-03-28

2100306-63-4, N-(Boc-PEG1)-N-bis(PEG2-propargyl)Related Search:


  • N-(Boc-PEG1)-N-bis(PEG2-propargyl)
  • 5,11,14-Trioxa-2,8-diazaheptadec-16-ynoic acid, 8-[2-[2-(2-propyn-1-yloxy)ethoxy]ethyl]-, 1,1-dimethylethyl ester
  • 2100306-63-4
  • C23H40N2O7