ChemicalBook > CAS DataBase List > ADDA 5 hydrochloride
ADDA 5 hydrochloride
- Product Name
- ADDA 5 hydrochloride
- CAS No.
- 473268-46-1
- Chemical Name
- ADDA 5 hydrochloride
- Synonyms
- ADDA-5);ADDA 5 HCl;ADDA 5 (ADDA5;ADDA 5 hydrochloride;ADDA 5 hydrochloride >=98% (HPLC)
- CBNumber
- CB53386447
- Molecular Formula
- C24H36ClNO2
- Formula Weight
- 406.01
- MOL File
- 473268-46-1.mol
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ADDA 5 hydrochloride Property
- storage temp.
- Store at -20°C
- solubility
- DMSO : 65 mg/mL (160.10 mM)
- form
- Solid
- color
- White to off-white
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- SML1940
- Product name
- ADDA 5 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 5 mg
- Price
- $108
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- SML1940
- Product name
- ADDA 5 hydrochloride
- Purity
- ≥98% (HPLC)
- Packaging
- 25 mg
- Price
- $347
- Updated
- 2025/07/31
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ADDA 5 hydrochloride Chemical Properties,Usage,Production
Uses
ADDA 5 hydrochloride has been used as a complex IV inhibitor to study its effects on leptomeningeal derivatives of human breast and lung cancer cells.
Biological Activity
ADDA 5 is a potent and selective inhibitor of cytochrome c oxidase (Complex IV) th at depletes the bioenergetics reserve capacity in intact glioma cells. ADDA 5 specifically inhibits the proliferation of chemosensitive and chemoresistant glioma cells, while sparing non-cancer cells. Additionally ADDA 5 is effective against glioma stem cells.
in vivo
ADDA 5 (8 mg/kg, i.p.) significantly suppresses the growth of tumor in mice. ADDA 5 does not causes detectable toxicity at up to 80 mg/kg in mice[1].
ADDA 5 hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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