SAR405 R enantiomer

Product Name: SAR405 R enantiomer
CAS No.: 1946010-79-2
Chemical Name: SAR405 R enantiomer
Synonyms: SAR405 R enantiomer;SAR405 R enantiomer, 10 mM in DMSO;SAR-405 R enantiomer,Inhibitor,SAR405 R enantiomer,inhibit;4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8R)-
CBNumber: CB53386513
Molecular Formula: C19H21ClF3N5O2
Formula Weight: 443.85
MOL File: 1946010-79-2.mol

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SAR405 R enantiomer Property

Boiling point:: 526.5±60.0 °C(Predicted)
Density: 1.51±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: Soluble in DMSO
pka: 3.29±0.20(Predicted)
form: Solid
color: White to off-white

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Crysdot

Product number: CD11174554
Product name: (R)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
Purity: 95+%
Packaging: 1g
Price: $520
Updated: 2021/12/16

Alichem

Product number: 1946010792
Product name: (R)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
Packaging: 1g
Price: $577.5
Updated: 2021/12/16

Crysdot

Product number: CD11174554
Product name: (R)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
Purity: 95+%
Packaging: 5g
Price: $1712
Updated: 2021/12/16

Alichem

Product number: 1946010792
Product name: (R)-1-((5-Chloropyridin-3-yl)methyl)-8-((R)-3-methylmorpholino)-2-(trifluoromethyl)-3,4-dihydro-1H-pyrimido[1,2-a]pyrimidin-6(2H)-one
Packaging: 5g
Price: $1794
Updated: 2021/12/16

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SAR405 R enantiomer Chemical Properties,Usage,Production

Uses

SAR405 R enantiomer is the less active enantiomer of SAR405. SAR405 is a PIK3C3/Vps34 inhibitor.

References

[1] Pasquier B. SAR405, a PIK3C3/Vps34 inhibitor that prevents autophagy and synergizes with MTOR inhibition in tumor cells. Autophagy. 2015 Apr 3;11(4):725-6. DOI:10.1080/15548627.2015.1033601

SAR405 R enantiomer Preparation Products And Raw materials

Raw materials

Preparation Products

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SAR405 R enantiomer Suppliers

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1946010-79-2, SAR405 R enantiomerRelated Search:

SAR405 R enantiomer

4H-Pyrimido[1,2-a]pyrimidin-4-one, 9-[(5-chloro-3-pyridinyl)methyl]-6,7,8,9-tetrahydro-2-[(3R)-3-methyl-4-morpholinyl]-8-(trifluoromethyl)-, (8R)-

SAR-405 R enantiomer,Inhibitor,SAR405 R enantiomer,inhibit

SAR405 R enantiomer, 10 mM in DMSO

1946010-79-2