Lefamulin acetate
- Product Name
- Lefamulin acetate
- CAS No.
- 1350636-82-6
- Chemical Name
- Lefamulin acetate
- Synonyms
- Lefamulin acetate;BC-3781 ACETATE;Lefamulin Acetat;BC-3781;BC 3781;BC3781;Lefamulin acetate (Xenleta);WSMXIQXWHPSVDE-WHAUHWDVSA-N;Lefamulin acetate (BC-3781 acetate);WSMXIQXWHPSVDE-WHAUHWDVSA-N USP/EP/BP;Inhibitor,Lefamulin,BC 3781,BC3781,Lefamulin acetate,inhibit,BC-3781,Bacterial,Antibiotic;(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate acetate
- CBNumber
- CB53399603
- Molecular Formula
- C30H49NO7S
- Formula Weight
- 567.78
- MOL File
- 1350636-82-6.mol
Lefamulin acetate Property
- storage temp.
- Store at -20°C
- solubility
- DMSO:100.0(Max Conc. mg/mL);176.12(Max Conc. mM)
- form
- Solid
- color
- White to off-white
- InChI
- InChI=1/C28H45NO5S.C2H4O2/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28;1-2(3)4/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3;1H3,(H,3,4)/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27?,28?;/s3
- InChIKey
- WSMXIQXWHPSVDE-IHBHSJRLNA-N
- SMILES
- C(=O)(O)C.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CS[C@@H]2CC[C@@H](N)C[C@H]2O)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:5,6,7,9,15,18,21,24,33,r|
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H317May cause an allergic skin reaction
H318Causes serious eye damage
H330Fatal if inhaled
- Precautionary statements
-
P260Do not breathe dust/fume/gas/mist/vapours/spray.
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P271Use only outdoors or in a well-ventilated area.
P272Contaminated work clothing should not be allowed out of the workplace.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P284Wear respiratory protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P310Immediately call a POISON CENTER or doctor/physician.
P320Specific treatment is urgent (see … on this label).
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P363Wash contaminated clothing before reuse.
P403+P233Store in a well-ventilated place. Keep container tightly closed.
P405Store locked up.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- CS-0012946
- Product name
- Lefamulin(acetate)
- Purity
- 98.02%
- Packaging
- 5mg
- Price
- $350
- Updated
- 2021/12/16
- Product number
- CS-0012946
- Product name
- Lefamulin(acetate)
- Purity
- 98.02%
- Packaging
- 10mg
- Price
- $550
- Updated
- 2021/12/16
- Product number
- CS-0012946
- Product name
- Lefamulin(acetate)
- Purity
- 98.02%
- Packaging
- 50mg
- Price
- $1100
- Updated
- 2021/12/16
- Product number
- orb573027
- Product name
- Lefamulin acetate
- Purity
- >98%
- Packaging
- 50mg
- Price
- $1356.6
- Updated
- 2021/12/16
- Product number
- CS-0012946
- Product name
- Lefamulin(acetate)
- Purity
- 98.02%
- Packaging
- 100mg
- Price
- $1800
- Updated
- 2021/12/16
Lefamulin acetate Chemical Properties,Usage,Production
Chemical Properties
Lefamulin acetate is a white to off-white solid. It is a stable compound (requiring no special storage conditions) which is highly soluble in water and 0.9% sodium chloride solution (>300mg/ml). The hydration level of lefamulin acetate at ambient conditions is typically below 1% w/w.
Uses
Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia.
Definition
Lefamulin acetate is a single stereoisomer semi-synthetically derived from pleuromutilin, a homochiral, natural fermentation product of known absolute stereochemistry. Lefamulin acetate is a diastereomer with R-configuration at carbons of the cyclohexane moiety. The absolute configuration of the active substance has been confirmed by single-crystal structure determination.
Lefamulin acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from Lefamulin acetate manufacturers
- Product
- Lefamulin Acetate 1350636-82-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- 98% HPLC
- Supply Ability
- 100kgs
- Release date
- 2023-08-14
- Product
- Lefamulin Acetat 1350636-82-6
- Price
- US $0.00/g
- Min. Order
- 1g
- Purity
- More Than 99%
- Supply Ability
- 100kg/Month
- Release date
- 2024-07-24
- Product
- Lefamulin acetate 1350636-82-6
- Price
- US $0.00-0.00/g
- Min. Order
- 1g
- Purity
- 98%+
- Supply Ability
- 100kgs
- Release date
- 2021-05-21