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Lefamulin acetate

Product Name
Lefamulin acetate
CAS No.
1350636-82-6
Chemical Name
Lefamulin acetate
Synonyms
Lefamulin acetate;BC-3781 ACETATE;Lefamulin Acetat;BC-3781;BC 3781;BC3781;Lefamulin acetate (Xenleta);WSMXIQXWHPSVDE-WHAUHWDVSA-N;Lefamulin acetate (BC-3781 acetate);WSMXIQXWHPSVDE-WHAUHWDVSA-N USP/EP/BP;Inhibitor,Lefamulin,BC 3781,BC3781,Lefamulin acetate,inhibit,BC-3781,Bacterial,Antibiotic;(3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate acetate
CBNumber
CB53399603
Molecular Formula
C30H49NO7S
Formula Weight
567.78
MOL File
1350636-82-6.mol
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Lefamulin acetate Property

storage temp. 
Store at -20°C
solubility 
DMSO:100.0(Max Conc. mg/mL);176.12(Max Conc. mM)
form 
Solid
color 
White to off-white
InChI
InChI=1/C28H45NO5S.C2H4O2/c1-6-26(4)14-22(34-23(32)15-35-21-8-7-18(29)13-20(21)31)27(5)16(2)9-11-28(17(3)25(26)33)12-10-19(30)24(27)28;1-2(3)4/h6,16-18,20-22,24-25,31,33H,1,7-15,29H2,2-5H3;1H3,(H,3,4)/t16-,17+,18-,20-,21-,22-,24+,25+,26-,27?,28?;/s3
InChIKey
WSMXIQXWHPSVDE-IHBHSJRLNA-N
SMILES
C(=O)(O)C.C[C@H]1[C@@H]([C@](C[C@@H](OC(=O)CS[C@@H]2CC[C@@H](N)C[C@H]2O)C2([C@H](C)CCC31CCC(=O)[C@]32[H])C)(C)C=C)O |&1:5,6,7,9,15,18,21,24,33,r|
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H317May cause an allergic skin reaction

H318Causes serious eye damage

H330Fatal if inhaled

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P284Wear respiratory protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P320Specific treatment is urgent (see … on this label).

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P363Wash contaminated clothing before reuse.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0012946
Product name
Lefamulin(acetate)
Purity
98.02%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0012946
Product name
Lefamulin(acetate)
Purity
98.02%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0012946
Product name
Lefamulin(acetate)
Purity
98.02%
Packaging
50mg
Price
$1100
Updated
2021/12/16
Biorbyt Ltd
Product number
orb573027
Product name
Lefamulin acetate
Purity
>98%
Packaging
50mg
Price
$1356.6
Updated
2021/12/16
ChemScene
Product number
CS-0012946
Product name
Lefamulin(acetate)
Purity
98.02%
Packaging
100mg
Price
$1800
Updated
2021/12/16
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Lefamulin acetate Chemical Properties,Usage,Production

Chemical Properties

Lefamulin acetate is a white to off-white solid. It is a stable compound (requiring no special storage conditions) which is highly soluble in water and 0.9% sodium chloride solution (>300mg/ml). The hydration level of lefamulin acetate at ambient conditions is typically below 1% w/w.

Uses

Lefamulin (BC-3781) acetate is an orally active antibiotic. Lefamulin acetate inhibits protein synthesis by binding to the peptidyl transferase center of the 50S bacterial ribosome. Lefamulin acetate has anti-inflammatory activity. Lefamulin acetate can be used in the research of bacterial infections, such as bacterial pneumonia.

Definition

Lefamulin acetate is a single stereoisomer semi-synthetically derived from pleuromutilin, a homochiral, natural fermentation product of known absolute stereochemistry. Lefamulin acetate is a diastereomer with R-configuration at carbons of the cyclohexane moiety. The absolute configuration of the active substance has been confirmed by single-crystal structure determination.

Lefamulin acetate Preparation Products And Raw materials

Raw materials

Preparation Products

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Lefamulin acetate Suppliers

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View Lastest Price from Lefamulin acetate manufacturers

shandong perfect biotechnology co.ltd
Product
Lefamulin Acetate 1350636-82-6
Price
US $0.00/g
Min. Order
1g
Purity
98% HPLC
Supply Ability
100kgs
Release date
2023-08-14
BEIJING SJAR TECHNOLOGY DEVELOPMENT CO., LTD.
Product
Lefamulin Acetat 1350636-82-6
Price
US $0.00/g
Min. Order
1g
Purity
More Than 99%
Supply Ability
100kg/Month
Release date
2024-07-24
Wuhan Nutra Biotechnology Co.,Ltd
Product
Lefamulin acetate 1350636-82-6
Price
US $0.00-0.00/g
Min. Order
1g
Purity
98%+
Supply Ability
100kgs
Release date
2021-05-21

1350636-82-6, Lefamulin acetateRelated Search:


  • WSMXIQXWHPSVDE-WHAUHWDVSA-N
  • BC-3781;BC 3781;BC3781
  • Lefamulin acetate
  • BC-3781 ACETATE
  • Lefamulin acetate (BC-3781 acetate)
  • WSMXIQXWHPSVDE-WHAUHWDVSA-N USP/EP/BP
  • Inhibitor,Lefamulin,BC 3781,BC3781,Lefamulin acetate,inhibit,BC-3781,Bacterial,Antibiotic
  • Lefamulin acetate (Xenleta)
  • Lefamulin Acetat
  • (3aR,4R,5R,7S,8S,9R,9aS,12R)-8-Hydroxy-4,7,9,12-tetramethyl-3-oxo-7-vinyldecahydro-4,9a-propanocyclopenta[8]annulen-5-yl 2-(((1R,2R,4R)-4-amino-2-hydroxycyclohexyl)thio)acetate acetate
  • 1350636-82-6