ChemicalBook > CAS DataBase List > N'-Cbz-L-ornithine

N'-Cbz-L-ornithine

Product Name
N'-Cbz-L-ornithine
CAS No.
3304-51-6
Chemical Name
N'-Cbz-L-ornithine
Synonyms
Orn(Z);Z-ORN-OH;H-ORN(Z)-OH;N-ORN(Z)-OH;l-orn(z)-oh;L-Orn(Cbz)-OH;N-D-CBZ-L-ORN;H-L-ORN(Z)-OH;H-ORN(CBZ)-OH;N5-Cbz-Orn-OH
CBNumber
CB5343696
Molecular Formula
C13H18N2O4
Formula Weight
266.29
MOL File
3304-51-6.mol
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N'-Cbz-L-ornithine Property

Melting point:
248-252℃
Boiling point:
492.2±45.0 °C(Predicted)
Density 
1.234±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
solubility 
Acidic Alcohol (Sparingly), Aqueous Acid (Slightly)
pka
2.51±0.24(Predicted)
form 
Solid
color 
White
CAS DataBase Reference
3304-51-6(CAS DataBase Reference)
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

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N-Bromosuccinimide Price

TRC
Product number
O671015
Product name
L-Orn(Z)-OH
Packaging
1g
Price
$45
Updated
2021/12/16
AK Scientific
Product number
J90695
Product name
L-Orn(Z)-OH
Packaging
1g
Price
$10
Updated
2021/12/16
Chem-Impex
Product number
02223
Product name
-Z-L-ornithine
Purity
≥ 98% (HPLC)
Packaging
5G
Price
$12.5
Updated
2021/12/16
AK Scientific
Product number
J90695
Product name
L-Orn(Z)-OH
Packaging
5g
Price
$14
Updated
2021/12/16
Chem-Impex
Product number
02223
Product name
Nδ-Z-L-ornithine,98%(HPLC)
Purity
98%(HPLC)
Packaging
25G
Price
$33.6
Updated
2021/12/16
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N'-Cbz-L-ornithine Chemical Properties,Usage,Production

Chemical Properties

White powder

Uses

L-Orn(Z)-OH is used as a reactant in the synthesis of cyclic aminohexapeptides which showed antifungal activity.

Synthesis

3184-13-2

501-53-1

3304-51-6

The general procedure for the synthesis of (S)-2-amino-5-(((benzyloxy)carbonyl)amino)pentanoic acid from L-ornithine hydrochloride and benzyl chloroformate was as follows: 7.5 g of L-ornithine hydrochloride was dissolved in 89 mL of 0.5 mol/L sodium hydroxide solution, 5.55 g of anhydrous copper sulfate was added, and the reaction was carried out for 15 minutes. Subsequently, 6.15 g of anhydrous potassium carbonate and 8.2 mL of benzyl chloroformate were added and the reaction mixture was stirred at room temperature overnight. After completion of the reaction, the filtrate was washed to give a blue solid. The solid was treated with saturated disodium ethylenediaminetetraacetic acid solution, which was first heated to reflux for 2 hours and then left at room temperature overnight. Finally, the filtrate was filtered and dried to give a white solid product in 83% yield.

References

[1] Patent: CN104788431, 2017, B. Location in patent: Paragraph 0055; 0056
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2009, vol. 52, # 2, p. 29 - 32
[3] Tetrahedron, 1999, vol. 55, # 33, p. 10201 - 10220
[4] Journal of the Chemical Society [Section] C: Organic, 1971, p. 3743 - 3748
[5] Journal of Agricultural and Food Chemistry, 1999, vol. 47, # 3, p. 939 - 944

N'-Cbz-L-ornithine Preparation Products And Raw materials

Raw materials

Preparation Products

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N'-Cbz-L-ornithine Suppliers

China 163 Germany 5 India 6 Japan 4 Switzerland 2 United Kingdom 7 United States 26 Global 213
J & K SCIENTIFIC LTD.
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18210857532; 18210857532
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86-10-82849933
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jkinfo@jkchemical.com
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China
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Meryer (Shanghai) Chemical Technology Co., Ltd.
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4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
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China
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Alfa Aesar
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400-6106006
Fax
021-67582001/03/05
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saleschina@alfa-asia.com
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China
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Energy Chemical
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021-021-58432009 400-005-6266
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021-58436166
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China
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GL Biochem (Shanghai) Ltd
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86-21-61263399
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ymbetter@glbiochem.com
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Capot Chemical Co., Ltd
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+86 (0) 571 85 58 67 18
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0086-571-85864795
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Shanghai Sinch Parmaceuticals Tech. Co. Ltd.
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+86-21-54096319
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sales@sinch.com.cn
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956
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0573-85285100
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isenchem@163.com
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China
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66
Adamas Reagent, Ltd.
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400-6009262 16621234537
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021-64823266
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chenyj@titansci.com
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China
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14101
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Shanghai Hanhong Scientific Co.,Ltd.
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021-54306202 13764082696
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info@hanhongsci.com
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China
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42934
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3304-51-6, N'-Cbz-L-ornithineRelated Search:

L-Ornithine Trimethoprim N-Carbobenzyloxyglycine N-δ-Boc-L-Ornithine H-Orn(2-Cl-Z)-OH N-Cbz-L-Leucine N-Cbz-L-histidine N-Cbz-L-Phenylalanine N-CBZ-L-glutamyl-L-tyrosine USP/EP/BP N-Cbz-L-Isoleucine H-Orn(Boc)-OBzl·HCl H-ORN(FMOC)-OH H-Orn(Tfa)-OH H-Orn(Trt)-OH H-Orn(Boc)-OtBu.HCl N(delta)-acetylornithine Ethyl L-ornithine dihydrochloride H-ORN(BOC)-OME HCL

  • L-ORNITHINE(CBZ)
  • H-ORN(Z)-OH
  • H-ORN(CBZ)-OH
  • Orn(Z)
  • L-Orn(Cbz)-OH
  • Nd-Z-L-ornithine≥ 98% (HPLC)
  • (2S)-2-amino-5-{[(benzyloxy)carbonyl]amino}pentanoic acid
  • N5-Cbz-L-ornithine
  • H-L-ORN(Z)-OH
  • N-D-CBZ-L-ORN
  • N-DELTA-Z-L-ORNITHINE
  • N-DELTA-BENZYLOXYCARBONYL-L-ORNITHINE
  • N-DELTA-CARBOBENZOXY-L-ORNITHINE
  • N-DELTA-CARBOBENZYLOXY-L-ORNITHINE
  • N-DELTA-CBZ-L-ORNITHINE
  • N-ORN(Z)-OH
  • ORNITHINE(Z)-OH
  • Z-ORN-OH
  • N<SUB>δ</SUB>-Cbz-L-ornithine
  • N-?-CBZ-L-Ornithine N-?-Carbobenzyloxy-L-ornithine
  • N-5-BENZYLOXYCARBONYL-L-ORNITHINE
  • N5-benzyloxycarbonyl-L-ornithine
  • N--Benzyloxycarbonyl-L-ornithine
  • l-orn(z)-oh
  • N'-Cbz-L-ornithine
  • Z-L-ORNITHINE extrapure
  • (S)-2-Amino-5-[[(benzyloxy)carbonyl]amino]pentanoic acid
  • N5-[(Phenylmethoxy)carbonyl]-L-ornithine
  • N5-Cbz-Orn-OH
  • 2-amino-5-(benzyloxycarbonylamino)valeric acid
  • 2-amino-5-(phenylmethoxycarbonylamino)pentanoic acid
  • 2-azanyl-5-(phenylmethoxycarbonylamino)pentanoic acid
  • N-D-BENZYLOXYCARBONYL-LORNITHINE
  • N-Δ-Z-L-ORNITHINE
  • Ornithine, N5-[(phenylmethoxy)carbonyl]-
  • L-Ornithine, N5-[(phenylmethoxy)carbonyl]-
  • N^d-Benzyloxycarbonyl-L-ornithine,98%
  • N'-Cbz-L-ornithine USP/EP/BP
  • 3304-51-6
  • Modified Amino Acids
  • I - Z
  • BioChemical
  • Biochemicals and Reagents
  • Amino Acids and Peptides
  • Ornithine [Org]
  • Amino Acids and Derivatives
  • Z-Amino acid series
  • Amino Acids