ChemicalBook > CAS DataBase List > 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)

Product Name: 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)
CAS No.: 16409-43-1
Chemical Name: 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)
Synonyms: ROSE OXIDE;2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-;(Z)-Rose oxide;ISOBUTENYL METHYLTETRAHYDROPYRAN;TETRAHYDRO-4-METHYL-2-(2-METHYL-1-PROPENYL)-2H-PYRAN;ROSE OXIDE RACEMIC;Rosoxide;FEMA 3236;rosenoxide;c-rose oxide
CBNumber: CB5344138
Molecular Formula: C10H18O
Formula Weight: 154.25
MOL File: 16409-43-1.mol

Less

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) Property

Boiling point:: 86 °C20 mm Hg(lit.)
Density: 0.873 g/mL at 20 °C(lit.)
vapor pressure: 53Pa at 20℃
refractive index: n20/D 1.454
FEMA: 3236 | TETRAHYDRO-4-METHYL-2-(2-METHYLPROPEN-1-YL)PYRAN
Flash point:: 157 °F
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
color: A colourless mobile liquid.
Odor: at 1.00 % in dipropylene glycol. green red rose spicy fresh geranium
Odor Type: floral
biological source: synthetic
optical activity: [α]20/D 28±1°, neat
Water Solubility: 920mg/L at 20℃
JECFA Number: 1237
BRN: 1680588
LogP: 3.3 at 23℃
CAS DataBase Reference: 16409-43-1(CAS DataBase Reference)
EPA Substance Registry System: 2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-propenyl)- (16409-43-1)

Less

Safety

Hazard Codes: Xi
Risk Statements: 38-36/37/38
Safety Statements: 36-26
WGK Germany: 3
RTECS: UQ1470000
F: 10-23
HS Code: 29329990
Toxicity: The acute oral LD₅₀ value in rats was reported as 4.3 g/kg (3.7-4.9 g/kg) and the acute dermal LD₅₀ value in rabbits as > 5 g/kg (Moreno, 1973).

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: W323608
Product name: Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran
Purity: mixture of cis and trans, ≥98%, stabilized, FG
Packaging: 1 unit
Price: $61.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: W323608
Product name: Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran
Purity: mixture of cis and trans, ≥98%, stabilized, FG
Packaging: 1 unit
Price: $61.7
Updated: 2025/07/31

Sigma-Aldrich

Product number: W323608
Product name: Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran
Purity: mixture of cis and trans, ≥98%, stabilized, FG
Packaging: 1kg
Price: $262
Updated: 2025/07/31

Sigma-Aldrich

Product number: 83917
Product name: (?)-Rose oxide
Purity: analytical standard
Packaging: 1ml
Price: $59.5
Updated: 2025/07/31

Sigma-Aldrich

Product number: W323608
Product name: Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran
Purity: mixture of cis and trans, ≥98%, stabilized, FG
Packaging: 100g
Price: $81.2
Updated: 2023/01/07

Less

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) Chemical Properties,Usage,Production

Chemical Properties

Rose Oxide occurs in small quantities, mainly as the levorotatory cis form, in essential oils (e.g., Bulgarian rose oil and geranium oil). Commercial synthetic products are either optically active or inactive mixtures of the cis- and trans-isomers. Their sensory properties depend on the starting material and the method of synthesis.They are colorless liquids with a strong odor reminiscent of geranium and rose oil.

Chemical Properties

Tetrahydro-4-methyl-2-(2-methylpropen-1-yl)pyran has a powerful distinctive geranium top note.

Occurrence

Reported found in the oils of rose (Bulgarian) and geranium (Réunion); both the cis- and the trans-form have been reportedly isolated from geranium oil. Unidentified isomers reported found in black currant berries, passion fruit, some types of Thymus and white wine.

Uses

Refer to the productμs Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Definition

ChEBI: Rose oxide is a member of the class of oxanes that is tetrahydro-2H-pyran which is substituted at positions 2 and 4 by an isoprop-1-enyl group and a methyl group, respectively. Organic compound of the pyran class and the monoterpene class and a fragrance found in roses and rose oil. All four possible stereoisomers are known; the 2S,4R and 2S,4S diastereoisomers [also known as the (-)-cis- and (-)-trans-isomers, respectively] are the main constituents in several essential oils and are used as a food flavouring and in perfumes and cosmetics. It has a role as a plant metabolite. It is a monoterpenoid, a member of oxanes and an olefinic compound.

Preparation

Rose oxide is usually prepared from citronellol, which can be converted into a mixture of two allyl hydroperoxides by photosensitized oxidationwith singlet oxygen. Reduction of the hydroperoxideswith sodium sulfite yields the corresponding diols . Treatmentwith dilute sulfuric acid results in allylic rearrangement and spontaneous cyclization of one of the isomers; amixture of diastereoisomeric rose oxides is thus formed. The unreacted diol isomer is separated by distillation. (?)- Citronellol as the starting material yields an approximately 7 : 3 mixture of (?)-cisand (?)-trans-rose oxide. Higher proportions of the cis-isomer may be obtained by dehydration with a stronger acid.Other methods for the production of rose oxide starting from citronellol consist of halogenation–dehalogenation reactions of citronellol.
An alternative technical process does not use citronellol but starts from prenal [107-86-8] and 3-methyl-3-buten-1-ol [763-32-6]. Under acidic conditions, the reaction affords a mixture of isomers of dehydro rose oxide (C₁₀H₁₆O6; [1786- 08-9], [92356-05-3], [60857-05-8]). Subsequent hydrogenation using a ruthenium/alumina catalyst leads to rose oxide.The proportion of cis-isomer can be increased by isomerization under acidic conditions.

Taste threshold values

Taste characteristics at 20 ppm: green, vegetative and herbal with a citrus nuance.

Flammability and Explosibility

Non flammable

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) Preparation Products And Raw materials

Raw materials

Ethyl linalool

Preparation Products

Less

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) Suppliers

Americas 1 Australia 1 China 188 Europe 3 France 1 Germany 5 India 25 Italy 1 Japan 3 Mexico 1 South Korea 1 Spain 2 Switzerland 1 United Kingdom 8 United States 51 USA 1 Global 293

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

jiliang chemicals

Tel: 21-62165282 15801962796;
Fax: 021 61153784
Email: bidingchem@163.com
Country: China
ProdList: 1379
Advantage: 60

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527768836
Email: 1791901229@qq.com
Country: China
ProdList: 6950
Advantage: 52

Beijing Isomersyn Technology CO;LTD

Tel: 010-82954736 13391601435
Email: sales@isomersyn.com
Country: China
ProdList: 3295
Advantage: 57

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Sichuan Kulinan Technology Co., Ltd

Tel: 400-1166-196 18981987031
Fax: 028-84555506 800101999
Email: cdhxsj@163.com
Country: China
ProdList: 11705
Advantage: 57

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shanghai Jian Chao Chemical Technology Co., Ltd.

Tel: 150-2103-5486 18017383231
Fax: qq：2817624287
Email: 983544897@qq.com
Country: China
ProdList: 9342
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

Quzhou Juhua Friendship Co., Ltd

Tel: 0570-3066667
Fax: 0570-3063388
Country: China
ProdList: 3930
Advantage: 58

Beijing Universal Century Technology Co., Ltd.

Tel: 400-8706899
Fax: 400-8706899
Email: hysj_bj.com
Country: China
ProdList: 3583
Advantage: 55

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

Shanghai Balmxy Pharmaceutical Co., Ltd

Tel: 021-24206007 13764915196
Fax: 86-021-23027023
Email: sales@balmxy.com
Country: China
ProdList: 6874
Advantage: 55

Hubei Jusheng Technology Co.,Ltd

Tel: 027-59599241 18871490274
Fax: 027-59599241
Email: 1400878000@qq.com
Country: China
ProdList: 9858
Advantage: 58

Changsha Jing Kang New Material Technology Co., Ltd.

Tel: 0733-0731-85118349 18874718518
Fax: 0731-85118349
Email: 877634463@qq.com
Country: China
ProdList: 1864
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
Fax: QQ:3008007432
Email: 3008007409@qq.com
Country: China
ProdList: 71826
Advantage: 60

Shandong Xiya Chemical Co., Ltd.

Tel: 4009903999 13395398332
Fax: 0539-6365991
Email: sales@xiyashiji.com
Country: China
ProdList: 20794
Advantage: 60

Grader reagent

Tel: 18221735425
Email: sales@xinpingchem.com
Country: China
ProdList: 9942
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Wuhai Shuou Technology Co., Ltd.

Tel: 17792809151
Fax: 18872220797
Email: 2355916837@ycphar.com
Country: China
ProdList: 6133
Advantage: 55

Taian Jiaye Biotechnology Co.Ltd

Tel: 13127280945
Email: 285424065@qq.com
Country: China
ProdList: 9976
Advantage: 55

Shanghai Orgchem Co.,Ltd.

Tel: +86-21-5877 1921
Fax: +86-21-5877 1925
Email: info@chemofchina.com
Country: China
ProdList: 9653
Advantage: 55

Shandong Ono Chemical Co., Ltd.

Tel: 0539-6362799 20）
Fax: 0539-6362799（To 20）
Country: China
ProdList: 9998
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 021-021-52271985 17721149837
Fax: +86 (21) 52271987
Email: sales@9dingchem.com
Country: China
ProdList: 19800
Advantage: 60

Shanghai BaiShun Biological Technology Co., Ltd

Tel: 021-37581181
Fax: 021-57456066
Email: sales@chem-mall.com
Country: China
ProdList: 10330
Advantage: 58

Shanghai Zhen Li Biological Technology Co., Ltd

Tel: 021-16621358918; 18516310516
Fax: 13045646768
Email: zhenlipharma888@163.com
Country: China
ProdList: 19035
Advantage: 58

Aikon International Limited

Tel: 025-58859352 18068836627
Fax: 02557626880
Email: sales01@aikonchem.com
Country: China
ProdList: 16027
Advantage: 58

Wuhan FengyaoTonghui Chemical Products Co., Ltd.

Tel: 027-87466105 15377573527
Email: 2678564200@qq.com
Country: China
ProdList: 17987
Advantage: 58

QuZhou Rainfull Chemical Co.,Ltd.

Tel: 0570-3062289 13819008176 15068926975
Fax: 0570-3063388
Email: 527757556@qq.com
Country: China
ProdList: 2957
Advantage: 58

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400-6387771-6039 18920764717
Email: sales@heowns.com
Country: China
ProdList: 23771
Advantage: 60

Shanghai Shuai Sun Industrial Co., Ltd.

Tel: 021-37590756 57450129
Fax: 021-57450128
Country: China
ProdList: 4284
Advantage: 58

Hubei Xinyuanshun Pharmaceutical Chemical Co., Ltd.

Tel: 027-51831887 15337167856
Fax: 027-51837635 QQ1165326703
Email: hubeixinyuanshun@163.com
Country: China
ProdList: 10295
Advantage: 58

Chengdu Saint - Kay Biotechnology Co., Ltd.

Tel: 028-85157043 15882256948
Email: 676046971@qq.com
Country: China
ProdList: 4181
Advantage: 58

Shanghai Jizhi Biochemical Technology Co. Ltd.

Tel: 4009004166/18616739031 18616739031
Email: 3007523370@qq.com
Country: China
ProdList: 52687
Advantage: 58

Shanghai wencai New Material Technology Co., Ltd.

Tel: 15721586846
Fax: 15721586846
Email: wencaimat@163.com
Country: China
ProdList: 2794
Advantage: 58

Shenzhen Polymeri Biochemical Technology Co., Ltd.

Tel: +86-400-002-6226 +86-13028896684;
Email: sales@rrkchem.com
Country: China
ProdList: 57422
Advantage: 58

Henan Alpha Chemical Co., Ltd.

Tel: 0371-55055611 18137792234
Fax: QQ：3002694073
Email: 3002694073@qq.com
Country: China
ProdList: 9987
Advantage: 58

Shanghai Dingfen Chemical Technology Co., Ltd.

Tel: 021-37590756
Fax: 021-57450128
Email: 373600283@qq.com
Country: China
ProdList: 4995
Advantage: 58

Hebei Yanxi Chemical Co., Ltd.

Tel: +8618531123677
Email: faithe@yan-xi.com
Country: China
ProdList: 5853
Advantage: 58

ANHUI WITOP BIOTECH CO., LTD

Tel: +8615255079626
Email: eric@witopchemical.com
Country: China
ProdList: 23541
Advantage: 58

Shandong Zhishang New Material Co., Ltd.

Tel: +8617653113209
Email: sales002@sdzschem.com
Country: China
ProdList: 3049
Advantage: 58

Hefei TNJ Chemical Industry Co.,Ltd.

Tel: +86-0551-65418671 +8618949823763
Fax: 0551-65418697
Email: sales@tnjchem.com
Country: China
ProdList: 34563
Advantage: 58

ShanDong Look Chemical Co.,Ltd.

Tel: +8617653113219
Email: sales01@sdlookchemical.com
Country: China
ProdList: 2768
Advantage: 58

sgtlifesciences pvt ltd

Tel: +8617013299288
Email: dj@sgtlifesciences.com
Country: China
ProdList: 12373
Advantage: 58

Dayang Chem (Hangzhou) Co.,Ltd.

Tel: +86-0571-88938639 +8617705817739
Fax: +86-571-88938652，+86-571- 88492614
Email: info@dycnchem.com
Country: China
ProdList: 52846
Advantage: 58

Chemwill Asia Co.,Ltd.

Tel: 86-21-51086038
Fax: 86-21-51861608
Email: chemwill_asia@126.com
Country: CHINA
ProdList: 23912
Advantage: 58

Less

View Lastest Price from 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: FEMA 3236 16409-43-1
Price: US $1.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-10-24

Hebei Chuanghai Biotechnology Co., Ltd

Product: (Z)-Rose oxide 16409-43-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 500000kg
Release date: 2024-11-04

Hebei Zhuanglai Chemical Trading Co.,Ltd

Product: Rose Oxide 16409-43-1
Price: US $99.00-35.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20ton
Release date: 2024-05-16

16409-43-1, 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)Related Search:

MUCONOMYCIN A HT-2 TOXIN 4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture) 15-ACETOXY-3ALPHA,7ALPHA-DIHYDROXY-12,13-EPOXYTRICHOTHEC-9-EN-8-ONE T-2 TOXIN DIACETOXYSCIRPENOL 3-ACETYLDEOXYNIVALENOL Tetrahydropyran Isobutylene (-)-ROSE OXIDE RORIDIN E VERRUCAROL trichothecin T-2 TETRAOL VERRUCARINK T-2 TRIOL scirpentriol RORIDIN A

(Z)-Rose oxide

2-(2-methyl-1-propenyl)-4-methyltetrahydro-pyra

2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-

2H-Pyran, tetrahydro-4-methyl-2-(2-methylpropenyl)-

4-Methyl-2-(2-methyl-1-propenyl)tetrahydro-2H-pyran

c-rose oxide

Pyran, 2-(2-methyl-1-propenyl)-4-methyltetrahydro-

Pyran, tetrahydro-2-(2-methyl-1-propenyl)-4-methyl-

Rose oxide , I

Rose oxide cis

Rose oxide levo

tetrahydro-4-methyl-2-(2-methyl-1-propen-1-yl)-2H-Pyran

FEMA 3236

rosenoxide

Rosoxide

tetrahydro-2-(2-methyl-1-propenyl)-4-methyl-pyra

tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2h-pyra

tetrahydro-4-methyl-2-(2-methylpropenyl)-2h-pyra

tetrahydro-4-methyl-2-(2-methylpropenyl)-pyra

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran (cis- and trans- mixture)

4-Methyl-2-(2-methylprop-1-en-1-yl)

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran, 99%, mixture of cis and trans

ROSE OXIDE BRI

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran ROSE

ISOBUTENYL METHYLTETRAHYDROPYRAN

tetrahydro-4-methyl-2-(2-methylprop-1-enyl)pyran

4-METHYL-2-(2-METHYLPROPENYL)TETRAHYDRO-2H-PYRAN

(4S)-2-(2-METHYL-1-PROPENYL)-4-METHYLTETRAHYDROPYRAN

ROSE OXIDE

ROSE OXIDE HIGH CIS

ROSE OXIDE RACEMIC

TETRAHYDRO-4-METHYL-2-(2-METHYL-1-PROPENYL)-2H-PYRAN

TETRAHYDRO-4-METHYL-2(2'-METHYL PROPEN-1'-YL)-PYRAN

TETRAHYDRO-4-METHYL-2-(2-METHYL-1-PROPEN

(-)-ROSE OXIDE, TERPENE STANDARD

(-)-ROSE OXIDE, TERPENE STANDARD 99%

Tetrahydro-4-methyl-2(2'-methylpropen-1'-yl)pyrane

2-Isobutenyl 4-methyl tetrahydropyran

DL-Rose oxide

ROSENOXID INAKTIV

4-Methyl-2-(2-methyl-1-propenyl)-tetrahydropyran

(+)-Rose oxide, (4S)-2-(2-Methyl-1-propenyl)-4-methyltetrahydropyran

2-(2-Methyl-1-propenyl)-4-methyltetrahydro-2H-pyran

Pyran, 2-(2-methyl-1

4-Methyl-2-(2-Methyl-1-propenyl)tetrahydropyran (cis- and trans- Mixture)

2-(2-Methyl-1-Propenyl)-4-Methyltetrahydropyran Rose Oxide

2H-Pyran, tetrahydro-4-methyl-2-(2-methyl-1-p ropen-1-yl)-

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran(cis-andtrans-mixture)&gt

4-Methyl-2-(2-methyl-1-propenyl)tetrahydropyran USP/EP/BP

(4S)-4-methyl-2-(2-methylprop-1-en-1-yl)oxane

High Purity Fema 3236 Rose Oxide CAS 16409-43-1 with Best Price

TIANFU-CHEM CAS:16409-43-1 FEMA 3236

2-(2-methyl-1-propenyl)-4-methyltetrahydro-pyran

LEVO-ROSE OXIDE 969651

Tetrahydro-4-methyl-2-(2-methyl-1-propenyl)-2H-pyran

(?)-Rose oxide

4-Methyl-2-(2-methylprop-1-en-1-yl)tetrahydro-2H-pyran, mixture of cis and trans, ≥98%, stabilized

16409-43-1