3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER

Synthesis

Product Name: 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER
CAS No.: 793-19-1
Chemical Name: 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER
Synonyms: NSC 54971;DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE;DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE;diMethyl 3,3'-(benzylazanediyl)dipropanoate;dimethyl 3,3'-(benzylazanediyl)dipropionate;N,N-BIS(B-(METHOXYCARBONYL)ETHYL)BENZYLAMINE;3,3'-Benzyliminobis(propanoic acid methyl) ester;3,3'-(Benzylimino)dipropionic acid dimethyl ester;3,3'-(Benzylimino)bispropionic acid dimethyl ester;3,3'-(Benzylimino)bis(propionic acid methyl) ester
CBNumber: CB5344693
Molecular Formula: C15H21NO4
Formula Weight: 279.34
MOL File: 793-19-1.mol

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3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Property

Boiling point:: 150-161 °C(Press: 0.6 Torr)
Density: 1.108±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
solubility: Chloroform (Slightly), Methanol (Slightly)
form: Oil
pka: 5.79±0.50(Predicted)
color: Colourless to Pale Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: S535613
Product name: DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE
Purity: Aldrich<sup>CPR</sup>
Packaging: 1 unit
Price: $185
Updated: 2025/07/31

Sigma-Aldrich

Product number: S535613
Product name: DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE
Purity: AldrichCPR
Packaging: 250mg
Price: $179
Updated: 2024/03/01

TRC

Product number: B130175
Product name: 3-[Benzyl-(2-methoxycarbonylethyl)amino]propionicAcidMethylEster
Packaging: 500mg
Price: $120
Updated: 2021/12/16

AK Scientific

Product number: 2113AJ
Product name: 3-[Benzyl-(2-methoxycarbonyl-ethyl)-amino]-propionicacidmethylester
Packaging: 1g
Price: $234
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0118233
Product name: DIMETHYL 3,3'-(BENZYLAZANEDIYL)DIPROPANOATE
Purity: 95.00%
Packaging: 100G
Price: $4445.75
Updated: 2021/12/16

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3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Chemical Properties,Usage,Production

Synthesis

A neat mixture of methyl acrylate 129 (63 ml, 0.70 mol) and BnNH2 130 (25 g, 0.23 mol) was refluxed in the presence of Et3N (65 ml, 0.46 mol) overnight. Excess methyl acrylate was distilled off, the residue was taken in EtOAc and washed with water, brine, dried over anhydrous Na2SO4 and filtered. Solvent removed under reduced pressure. The resultant oil was chromatographed over silica gel using EtOAc-pet ether to furnish Michael adduct 131 as a yellow oil (58.67 g).

Uses

3-[Benzyl-(2-methoxycarbonylethyl)amino]propionic Acid Methyl Ester is used in preparation of substituted Phenyloxazolidinones as antimicrobial agents for treating antimicrobial.

References

[1] Patent: WO2017/15106, 2017, A1. Location in patent: Page/Page column 30
[2] Journal of Labelled Compounds and Radiopharmaceuticals, 2013, vol. 56, # 14, p. 722 - 725
[3] Planta Medica, 2017, vol. 83, # 5, p. 420 - 425
[4] Patent: US2017/274362, 2017, A1. Location in patent: Paragraph 0077-0079
[5] Patent: EP2570410, 2013, A1. Location in patent: Paragraph 0062

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER Suppliers

Canada 1 China 22 India 3 United Kingdom 3 United States 8 Global 37

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793-19-1, 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTERRelated Search:

N-BENZYL-N-BIS(TERT-BUTYLPROPIONATE) AMINE trans-Dimethyl 1-benzyl-3,4-pyrrolidinedicarboxylate N-(2-CARBETHOXYETHYL)-N-(2-CARBOMETHOXYPROPYL)BENZYLAMINE cis-Dimethyl 1-benzyl-3,4-pyrrolidinedicarboxylate 3-[BENZYL-(2-ETHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID ETHYL ESTER DIETHYL CIS-1-BENZYL-3,4-PYRROLIDINEDICARBOXYLATE 3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER

3-[BENZYL-(2-METHOXYCARBONYL-ETHYL)-AMINO]-PROPIONIC ACID METHYL ESTER

methyl N-benzyl-N-(3-methoxy-3-oxopropyl)-beta-alaninate

N,N-BIS(B-(METHOXYCARBONYL)ETHYL)BENZYLAMINE

3,3'-(Benzylimino)bis(propionic acid methyl) ester

3,3'-(Benzylimino)bispropionic acid dimethyl ester

3,3'-(Benzylimino)dipropionic acid dimethyl ester

3,3'-Benzyliminobis(propanoic acid methyl) ester

N-(3-Methoxy-3-oxopropyl)-N-phenylmethyl-β-alanine methyl ester

3-[benzyl-(3-keto-3-methoxy-propyl)amino]propionic acid methyl ester

methyl 3-[(3-methoxy-3-oxo-propyl)-(phenylmethyl)amino]propanoate

methyl 3-[(3-methoxy-3-oxopropyl)-(phenylmethyl)amino]propanoate

diMethyl 3,3'-(benzylazanediyl)dipropanoate

NSC 54971

phenanthro(1,2-b)furan-10,11-dione, 6,7,8,9-tetrahydro-7-hydroxy-1-methyl-6-methylene-

Methyl 3-[benzyl-(3-methoxy-3-oxo-propyl)amino]propanoate

dimethyl 3,3'-(benzylazanediyl)dipropionate

DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE

7-hydroxy-1-methyl-6-methylene-8,9-dihydro-7H-naphtho[1,2-g]benzofuran-10,11-dione

β-Alanine, N-(3-methoxy-3-oxopropyl)-N-(phenylmethyl)-, methyl ester

β-Alanine, N-(3-methoxy-3-oxopropyl)-N-(phenylmethyl)-, methyl estermethyl 3-[benzyl(3-methoxy-3-oxopropyl)amino]propanoate

Methyl N-benzyl-N-(3-methoxy-3-oxopropyl)-β-alaninate

DIMETHYL 3,3'-(BENZYLIMINO)DIPROPIONATE

793-19-1