DIHYDROCYCLOSPORIN A

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DIHYDROCYCLOSPORIN A

Product Name: DIHYDROCYCLOSPORIN A
CAS No.: 59865-15-5
Chemical Name: DIHYDROCYCLOSPORIN A
Synonyms: CS-2523;Cyclosporin EP B;Dihydrocyclosporin;Capecitabine Imp.G;DIHYDROCYCLOSPORIN A;Dihydrocyclosporine A;Cyclosporin Impurity 10;Cyclosporine Impurity 10;Ciclosporin EP impurity B;Dihydrocyclosporin A reference
CBNumber: CB5352728
Molecular Formula: C62H113N11O12
Formula Weight: 1204.63
MOL File: 59865-15-5.mol

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DIHYDROCYCLOSPORIN A Property

Melting point:: 120-125?C
Boiling point:: 1285.3±65.0 °C(Predicted)
Density: 1.012±0.06 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: Solid
pka: 13.33±0.70(Predicted)
color: White
InChIKey: TYFOVYYNQGNDKH-AAJDKDKZNA-N

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H350May cause cancer

H362May cause harm to breast-fed children

Precautionary statements

P201Obtain special instructions before use.

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P263Avoid contact during pregnancy/while nursing.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TRC

Product number: D448865
Product name: DihydroCyclosporinA
Packaging: 5mg
Price: $130
Updated: 2021/12/16

Usbiological

Product number: D3801-01
Product name: Dihydrocyclosporin A
Packaging: 1mg
Price: $362
Updated: 2021/12/16

TRC

Product number: D448865
Product name: DihydroCyclosporinA
Packaging: 100mg
Price: $1480
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: API0002365
Product name: DIHYDROCYCLOSPORIN A
Purity: 95.00%
Packaging: 100MG
Price: $1732.5
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FD21913
Product name: Dihydrocyclosporin A
Packaging: 25mg
Price: $700
Updated: 2021/12/16

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DIHYDROCYCLOSPORIN A Chemical Properties,Usage,Production

Chemical Properties

White Solid

Uses

Dihydrocyclosporin A is a closely related co-metabolite of cyclosporin A. Dihydrocyclosporin A possesses no immunosuppressant activity and has found use as a control to determine the role of immunosuppression in the pharmacology of cyclosporin A, particularly in the treatment of parasitic infections.

Uses

Dihydrocyclosporin A (DHCsA-d) is cyclosporine A (CsA) derivative. DHCsA-d significantly inhibited promastigotes and intracellular amastigotes, but it is highly cytotoxic.

Uses

A Cyclosporin A (C988900) analog, an immunosuppressant.

Side effects

Dihydrocyclosporine A has no obvious nephrotoxic effect, but it exhibits hepatotoxic effects, often leading to hypertension.

DIHYDROCYCLOSPORIN A Preparation Products And Raw materials

Raw materials

Preparation Products

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59865-15-5, DIHYDROCYCLOSPORIN ARelated Search:

DIHYDROCYCLOSPORIN C dihydrocyclosporin D Dihydrocyclosporin E DIHYDROCYCLOSPORIN A CYCLOSPORIN J

DIHYDROCYCLOSPORIN A

Dihydrocyclosporin

(3R,4R)-3-Hydroxy-4,N-dimethyl-5-propylcyclo[L-Nva-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-]

(3R,4R)-3-Hydroxy-N-methyl-5-propylcyclo(L-Leu-L-Abu-Sar-N-methyl-L-Leu-L-Val-N-methyl-L-Leu-L-Ala-D-Ala-N-methyl-L-Leu-N-methyl-L-Leu-N-methyl-L-Val-)

6-[(2S,3R,4R)-3-Hydroxy-4-Methyl-2-(MethylaMino)octanoic acid]cyclosporin A

Cyclosporin A Dihydro IMpurity

Dihydrocyclosporine A

Cyclosporin Impurity 10

Dihydrocyclosporin A reference

Dihydrocyclosporine A/6-[(2S,3R,4R)-3-Hydroxy-4-methyl-2-(methylamino)octanoic acid]cyclosporin A

CS-2523

Cyclosporin Impurity 10（Dihydrocyclosporin A）

Cyclosporin A,6-[(2S,3R,4R)-3-hydroxy-4-methyl-2-(methylamino)octanoic acid]-

Capecitabine Imp.G

Cyclosporine Impurity 10

Ciclosporin EP impurity B

Cyclosporin Impurity 10(Dihydrocyclosporin A)(Ciclosporin EP Impurity B)

Ciclosporin EP Impurity B (Dihydrocyclosporin A)

Cyclosporin EP B

59865-15-5

C62H113N11O12

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