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DIMETHYLZINC

Product Name
DIMETHYLZINC
CAS No.
544-97-8
Chemical Name
DIMETHYLZINC
Synonyms
(CH3)2Zn;Dimethylzinc solution;methylzinc;zincmethyl;dimethyl-zin;DIMETHYLZINC;Dimethylzink;M in heptane;Zinc, dimethyl-;Dimethylzincmin
CBNumber
CB5353482
Molecular Formula
C2H6Zn
Formula Weight
95.46
MOL File
544-97-8.mol
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DIMETHYLZINC Property

Melting point:
-42°C
Boiling point:
44-46 °C
Density 
0.92 g/mL at 20 °C
Flash point:
30 °F
storage temp. 
0-6°C
form 
liquid
color 
colorless
Sensitive 
Air & Moisture Sensitive
Merck 
14,3263
BRN 
3587195
InChIKey
AXAZMDOAUQTMOW-UHFFFAOYSA-N
CAS DataBase Reference
544-97-8(CAS DataBase Reference)
EPA Substance Registry System
Zinc, dimethyl- (544-97-8)
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Safety

Hazard Codes 
F,C,N,Xn
Risk Statements 
11-14-34-50/53-65-67-63-51/53-48/20-17-14/15-36/38
Safety Statements 
26-45-61-62-60-43-36/37/39-33-29-16-46-43A-36/37
RIDADR 
UN 3399 4.3/PG 2
WGK Germany 
2
10-23
TSCA 
Yes
HazardClass 
4.2
PackingGroup 
I
HS Code 
29319090
Hazardous Substances Data
544-97-8(Hazardous Substances Data)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H225Highly Flammable liquid and vapour

H250Catches fire spontaneously if exposed to air

H252Self-heating in large quantities; may catch fire

H260In contact with water releases flammable gases which may ignite spontaneously

H261In contact with water releases flammable gas

H304May be fatal if swallowed and enters airways

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

H336May cause drowsiness or dizziness

H373May cause damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P222Do not allow contact with air.

P223Keep away from any possible contact with water, because of violent reaction and possible flash fire.

P231+P232Handle under inert gas. Protect from moisture.

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P370+P378In case of fire: Use … for extinction.

P405Store locked up.

P422Store contents under …

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
417246
Product name
Dimethylzinc solution
Purity
1.0 M in heptane
Packaging
50ml
Price
$323
Updated
2024/03/01
Sigma-Aldrich
Product number
364401
Product name
Dimethylzinc solution
Purity
2.0?M in toluene
Packaging
50mL
Price
$606
Updated
2024/03/01
Sigma-Aldrich
Product number
364401
Product name
Dimethylzinc solution
Purity
2.0?M in toluene
Packaging
500ml
Price
$3000
Updated
2024/03/01
Alfa Aesar
Product number
039563
Product name
Dimethylzinc, 96%
Packaging
25g
Price
$1044.65
Updated
2024/03/01
Strem Chemicals
Product number
30-5062
Product name
Dimethylzinc, min. 99% (10 wt% in hexanes) (Sure/Seal(TM) bottle)
Packaging
50g
Price
$302
Updated
2024/03/01
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DIMETHYLZINC Chemical Properties,Usage,Production

Chemical Properties

Clear colorless liquid

Uses

Dimethylzinc is pharmaceutical compound comprising Hemiasterlin derivatives and its antibody conjugate for treatment of cancer.

Uses

Dimethylzinc solution can be used as:

  • A catalyst with nickel for the stereoselective C?2 alkenylation and dialkenylation of pyridine derivatives by alkynes to give monoalkenylation products.
  • A reagent with aldehydes and 2-methoxyaniline for the synthesis of enantioselective alkyl and aralkyl secondary amines via one-pot three-component coupling reaction in the presence of zirconium tetraisopropoxide.
  • A methylating reagent for methylation of fluoroalkylated pyruvates in the presence of copper/chiral diphosphine catalyst.

Uses

Activator for radical trifluoromethylation of silyl enol ethers leading to α-trifluoromethyl ketones.1

Definition

ChEBI: Dimethylzinc is a dialkylzinc compound.

General Description

Mobile liquid, with peculiar garlic odor.

Air & Water Reactions

Highly flammable. Ignites in air and burns with a blue flame giving off a peculiar garlicky odor. Explodes in oxygen or ozone. Reacts violently with water to generate methane [Merck, 11th ed., 1989; Brauer(1965)]. Very slow oxidation with traces of air to give methylzinc methylate.

Reactivity Profile

DIMETHYLZINC is very reactive, acts as a strong reducing agent. Combines with acids, with alcohols (methanol, ethanol), and 2-2-dichloropropane as well as with water with explosive violence. When heated to decomposition emits toxic fumes of zinc oxide [Bretherick, 5th ed., 1995, p. 354]. Oxidants may yield peroxide formation, which is explosive.

Health Hazard

Inhalation of mist or vapor causes immediate irritation of upper respiratory tract. Excessive or prolonged inhalation of fumes from ignition or decomposition may cause ``metal fume fever'' (sore throat, headache, fever, chills, nausea, vomiting, muscular aches, perspiration, constricting sensation in lungs, weakness, sometimes prostration). Symptoms usually last 12-24 hrs. Eyes are immediately and severely irritated by liquid, vapor, or dilute solutions. If not removed by thorough flushing with water, chemical may permanently damage cornea. Skin will undergo thermal and acid burns when chemical reacts with moisture in skin. Unless washed quickly, skin may be scarred. Treat dilute solutions with same precautions as concentrated liquid. Ingestion, while unlikely, would cause immediate burns at site of contact. Nausea, vomiting, cramps, and diarrhea may follow. Tissues may ulcerate if not treated.

DIMETHYLZINC Preparation Products And Raw materials

Raw materials

Preparation Products

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DIMETHYLZINC Suppliers

Shaoxing Shangyu Hualun Chemical Co. Ltd.
Tel
0575-82732398 13735223794
Email
xchl@hualun-chem.com
Country
China
ProdList
6
Advantage
58
Huangshi Bo’Er Chemical Co., Ltd.
Tel
0714-6401888 18671400300
Fax
0714-6401888
Email
273568016@qq.com
Country
China
ProdList
545
Advantage
58
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44688
Advantage
61
Beijing Ouhe Technology Co., Ltd
Tel
010-82967028 13552068683
Fax
+86-10-82967029
Email
2355560935@qq.com
Country
China
ProdList
12390
Advantage
60
JinYan Chemicals(ShangHai) Co.,Ltd.
Tel
13817811078
Fax
86-021-50426522,50426273
Email
sales@jingyan-chemical.com
Country
China
ProdList
9976
Advantage
60
Jia Xing Isenchem Co.,Ltd
Tel
0573-85285100 18627885956
Fax
0573-85285100
Email
isenchem@163.com
Country
China
ProdList
9513
Advantage
66
Syntechem Co.,Ltd
Tel
Fax
E-Mail Inquiry
Email
info@syntechem.com
Country
China
ProdList
12984
Advantage
57
Thermo Fisher Scientific
Tel
800-810-5118
Fax
+86-10-84193589
Email
cnchemical@thermofisher.com
Country
China
ProdList
17770
Advantage
75
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View Lastest Price from DIMETHYLZINC manufacturers

Hebei Weibang Biotechnology Co., Ltd
Product
DIMETHYLZINC 544-97-8
Price
US $9.90/KG
Min. Order
1KG
Purity
99%
Supply Ability
5tons
Release date
2024-12-03
Shanghai UCHEM Inc.
Product
Dimethylzinc 544-97-8
Price
US $126.00-474.00/g
Min. Order
100g
Purity
1M in n-hexane
Supply Ability
25kg
Release date
2023-12-15
Hebei Mojin Biotechnology Co., Ltd
Product
DIMETHYLZINC 544-97-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-08-25

544-97-8, DIMETHYLZINCRelated Search:


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