ChemicalBook > CAS DataBase List > 5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN

Product Name
5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN
CAS No.
2784-27-2
Chemical Name
5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN
Synonyms
NSC 156081;hydroxyphenytoin;4-hydroxyphenytoin;p-hydroxyphenytoin;4-Hydroxydiphenylhy;para-hydroxyphenytoin;hydroxydiphenylhydantoin;4-hydroxydiphenylhydantoin;p-hydroxydiphenylhydantoin;5--5-phenyl-d5-hydantoin-13C3
CBNumber
CB5355815
Molecular Formula
C15H12N2O3
Formula Weight
268.27
MOL File
2784-27-2.mol
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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Property

Melting point:
>300 °C(lit.)
Boiling point:
411.43°C (rough estimate)
Density 
1.1992 (rough estimate)
refractive index 
1.5906 (estimate)
solubility 
soluble50mg/mL, clear, colorless to faintly yellow (DMF:MeOH(2:1))
form 
Solid
pka
8.37±0.10(Predicted)
color 
White to Off-White
Water Solubility 
36mg/L(37 ºC)
InChI
1S/C15H12N2O3/c18-12-8-6-11(7-9-12)15(10-4-2-1-3-5-10)13(19)16-14(20)17-15/h1-9,18H,(H2,16,17,19,20)
InChIKey
XEEDURHPFVXALT-UHFFFAOYSA-N
SMILES
Oc1ccc(cc1)C2(NC(=O)NC2=O)c3ccccc3
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
2
RTECS 
MU2485000
Storage Class
11 - Combustible Solids
Hazard Classifications
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
161543
Product name
5-(4-Hydroxyphenyl)-5-phenylhydantoin
Purity
98%
Packaging
1g
Price
$145
Updated
2023/06/20
TRC
Product number
H516770
Product name
5-(4-Hydroxyphenyl)-5-phenylhydantoin
Packaging
50mg
Price
$65
Updated
2021/12/16
Matrix Scientific
Product number
156061
Product name
5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione
Packaging
0.500g
Price
$100
Updated
2021/12/16
Matrix Scientific
Product number
156061
Product name
5-(4-Hydroxyphenyl)-5-phenylimidazolidine-2,4-dione
Packaging
1g
Price
$120
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
RME0000016
Product name
4-HYDROXYPHENYTOIN
Purity
95.00%
Packaging
1G
Price
$640.25
Updated
2021/12/16
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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Chemical Properties,Usage,Production

Uses

5-(4-Hydroxyphenyl)-5-phenylhydantoin was used in enantiomeric separation of chiral pharmaceuticals using a teicoplanin chiral stationary phase by aqueous and non-aqueous packed capillary electrochromatography. It was used as internal standard in determination of phenylbutazone and its metabolite oxyphenbutazone in human plasma by GLC.

Definition

ChEBI: A imidazolidine-2,4-dione that consists of hydantoin bearing phenyl and 4-hydroxyphenyl substituents at position 5.

General Description

5-(4-Hydroxyphenyl)-5-phenylhydantoin is the major metabolite of phenytoin.

5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOIN Suppliers

Shanghai Hanhong Scientific Co.,Ltd.
Tel
021-54306202 13764082696
Email
info@hanhongsci.com
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China
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Clearsynth Labs Limited
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+91-22-26355700
Fax
+91-22-26355701
Email
info@clearsynth.com
Country
India
ProdList
9679
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Sigma-Aldrich
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021-61415566 800-8193336
Email
orderCN@merckgroup.com
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China
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Amadis Chemical Company Limited
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571-89925085
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0086-571-89925065
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sales@amadischem.com
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China
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131957
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Aikon International Limited
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025-58859352 18068836627
Fax
(5)02557626880
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dt3@aikonchem.com
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China
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Tianjin heowns Biochemical Technology Co., Ltd.
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400-6387771-6039 18920764717
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sales@heowns.com
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China
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Nanjing Haolv Biotechnology Co.,Ltd
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025-84622273 17361806303
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kexin.zhou@haolvbiotech.com
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China
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Energy Chemical
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021-58432009 400-005-6266
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021-58436166
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marketing@energy-chemical.com
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China
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Yancheng Tongming Biotechnology Co., Ltd.
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15195160625
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2863565288@qq.com
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China
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Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
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029-029-81120477 17792793610
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1033@dideu.com
Country
China
ProdList
9989
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2784-27-2, 5-(4-HYDROXYPHENYL)-5-PHENYLHYDANTOINRelated Search:


  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-
  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl- (9CI)
  • 2,4-Imidazolidinedione, 5-(4-hydroxyphenyl)-5-phenyl-, (.+-.)-
  • 4-Hydroxydiphenylhy
  • (Hydroxyphenyl)phenylhydantoin
  • 5-(para-Hydroxyphenyl)-5-phenylhydantoin
  • (p-hydroxyphenyl)phenylhydantoin
  • 4-hydroxydiphenylhydantoin
  • 4-hydroxyphenytoin
  • 5-(4-hydroxyphenyl)-5-phenyl-4-imidazolidinedione
  • 5-(p-hydroxyphenyl)-5-phenyl-hydantoi
  • 5-(p-hydroxyphenyl)-5-phenylhydantoin
  • 5-p-hydroxyphenyl-5-phenylhydantoin
  • 5-(4-Hydroxyphenyl)-5-phenylhydantoin 98%
  • hydroxydiphenylhydantoin
  • hydroxyphenytoin
  • para-hydroxyphenytoin
  • p-hydroxydiphenylhydantoin
  • p-hydroxyphenytoin
  • 5-(4-hydroxyphenyl)-5-phenylimidazolidine-2,4-dione
  • 5--5-phenyl-d5-hydantoin-13C3
  • NSC 156081
  • 5-Phenyl-5-(4-hydroxyphenyl)imidazolidine-2,4-dione
  • 4-Hydroxyphenytoin (5- (4-Hydroxyphenyl)-5-phenylhydantoin)
  • 5-<WBR>(4-<WBR>Hydroxyphenyl)<WBR>-<WBR>5-<WBR>phenylhydantoin
  • 4-Hydroxyphenytoin (5-(4-Hydroxyphenyl)-5-phenylhydantoin) 0.1 mg/ml in Methanol
  • 2784-27-2
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  • Imidazolines/Imidazolidines
  • Heterocyclic Building Blocks
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  • Imidazolines/Imidazolidines