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IQHNJQKWEMCXAD-YYZTVXDQSA-N

Product Name
IQHNJQKWEMCXAD-YYZTVXDQSA-N
CAS No.
709026-60-8
Chemical Name
IQHNJQKWEMCXAD-YYZTVXDQSA-N
Synonyms
IQHNJQKWEMCXAD-YYZTVXDQSA-N;C16-Sphingosine-1-phosphate;Sphingosine-1-phosphate (d16:1);4-Hexadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)-
CBNumber
CB53577025
Molecular Formula
C16H34NO5P
Formula Weight
351.42
MOL File
709026-60-8.mol
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IQHNJQKWEMCXAD-YYZTVXDQSA-N Property

Boiling point:
528.2±60.0 °C(Predicted)
Density 
1.120±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
0.3 M NaOH: 4 mg/ml; DMF: <50 μg/ml; DMSO: <50 μg/ml; PBS (pH 7.2): <50 μg/ml
form 
A crystalline solid
pka
1.76±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
9002921
Product name
Sphingosine-1-phosphate (d16:1)
Purity
≥95%
Packaging
500μg
Price
$201
Updated
2024/03/01
Cayman Chemical
Product number
9002921
Product name
Sphingosine-1-phosphate (d16:1)
Purity
≥95%
Packaging
1mg
Price
$362
Updated
2024/03/01
Cayman Chemical
Product number
9002921
Product name
Sphingosine-1-phosphate (d16:1)
Purity
≥95%
Packaging
5mg
Price
$1161
Updated
2024/03/01
TRC
Product number
S680730
Product name
C16-Sphingosine-1-phosphate
Packaging
0.5mg
Price
$195
Updated
2021/12/16
AK Scientific
Product number
1273DJ
Product name
C16Sphingosine-1-phosphate
Packaging
5mg
Price
$1391
Updated
2021/12/16
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IQHNJQKWEMCXAD-YYZTVXDQSA-N Chemical Properties,Usage,Production

Description

C16 Sphingosine-1-phosphate (C16 S1P) is a derivative of sphingosine-1-phosphate (S1P; ) that binds to S1P1/EDG-1, S1P3/EDG-3, and S1P2/EDG-5 receptors with affinities of 115%, 83%, and 103%, respectively, relative to S1P in CHO cells. C16 S1P was increased in postmortem primary open angle glaucoma trabecular meshwork samples.

Uses

C16-Sphingosine-1-phosphate is an important regulator of a wide variety of biological processes acting as an endogenous ligand to EDG/S1P receptors.

Definition

ChEBI: Hexadecasphing-4-enine-1-phosphate is a sphingoid 1-phosphate that is hexadecasphing-4-enine substituted by a phospho group at position 1. It has a role as a mouse metabolite. It is functionally related to a hexadecasphing-4-enine.

References

[1] HYUN-SUK LIM . Syntheses of sphingosine-1-phosphate analogues and their interaction with EDG/S1P receptors[J]. Bioorganic & Medicinal Chemistry Letters, 2004, 14 10: Pages 2499-2503. DOI: 10.1016/j.bmcl.2004.03.001
[2] AYMAN J ALJOHANI. Human trabecular meshwork sphingolipid and ceramide profiles and potential latent fungal commensalism.[J]. Investigative ophthalmology & visual science, 2014: 3413-3422. DOI: 10.1167/iovs.13-13570

IQHNJQKWEMCXAD-YYZTVXDQSA-N Preparation Products And Raw materials

Raw materials

Preparation Products

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IQHNJQKWEMCXAD-YYZTVXDQSA-N Suppliers

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709026-60-8, IQHNJQKWEMCXAD-YYZTVXDQSA-NRelated Search:


  • IQHNJQKWEMCXAD-YYZTVXDQSA-N
  • Sphingosine-1-phosphate (d16:1)
  • C16-Sphingosine-1-phosphate
  • 4-Hexadecene-1,3-diol, 2-amino-, 1-(dihydrogen phosphate), (2S,3R,4E)-
  • 709026-60-8