ChemicalBook > CAS DataBase List > ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate

ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate

Product Name
ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
CAS No.
300803-69-4
Chemical Name
ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
Synonyms
STOML3 inhibitor OB-1;ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate;3-Benzofurancarboxylic acid, 5-[(1-methyl-4-nitro-1H-imidazol-5-yl)oxy]-2-phenyl-, ethyl ester
CBNumber
CB53577722
Molecular Formula
C21H17N3O6
Formula Weight
407.38
MOL File
300803-69-4.mol
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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Property

storage temp. 
Store at -20°C
solubility 
Soluble in DMSO
form 
A solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

DC Chemicals
Product number
002953
Product name
STOML3inhibitorOB-1
Packaging
004
Price
$1100
Updated
2021/12/16
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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Chemical Properties,Usage,Production

Biological Activity

OB-1 is an inhibitor of the oligomerization of Stomatin-like protein-3 (STOML3), which is a modulator of the mechanosensitive ion channel Piezo2. STOML3 requires oligomerization for its role as an endogenous regulator of the sensitivity of mechanosensitive Piezo ion channels in sensory neurons. By inhibiting this activity, OB-1 has been shown to reduce touch-evoked pain behavior in two mouse models of neuropathic pain.

storage

Store at RT

ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate Suppliers

OTAVA chemicals
Tel
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Fax
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Email
north.america@otavachemicals.com
Country
Ukraine
ProdList
6495
Advantage
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300803-69-4, ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylateRelated Search:


  • ethyl 5-((1-methyl-4-nitro-1H-imidazol-5-yl)oxy)-2-phenylbenzofuran-3-carboxylate
  • 3-Benzofurancarboxylic acid, 5-[(1-methyl-4-nitro-1H-imidazol-5-yl)oxy]-2-phenyl-, ethyl ester
  • STOML3 inhibitor OB-1
  • 300803-69-4