2',7'-DIFLUOROFLUORESCEIN Property

Boiling point:

591.7±50.0 °C(Predicted)

Density 

1.70±0.1 g/cm3(Predicted)

solubility 

Insoluble in water; soluble in N,Ndimethylformamide

form 

A solid

pka

4.8, (at 22℃);4.7, (at 22℃)

color 

Orange powder

λmax

490 nm (Buffer pH 9.0)

Major Application

As geothermal tracers;TiO2 nanoparticles for light energy conversion

Biological Applications

Detecting atherosclerosis;detecting/monitoring amyloid Aβ production/accumulation/aggregation/disaggregation; diagnosing Alzheimer’s disease;estimating/measuring concentration of cortisol, melatonin, secretory IgA in body fluids;11 evaluating cetuximab-based imaging probe to target epidermal growth factor receptor (EGFR);examining biodistribution of proteins;investigating/measuring protein-protein and protein-nucleic acid interactions;measuring pH of apoplast at the root surface;visualizing hair follicles;as a substrate for measuring β-lactamase activity,phosphatases activity

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

2',7'-DIFLUOROFLUORESCEIN Chemical Properties,Usage,Production

Uses

2'',7''-Difluorofluorescein is a reactant used in the synthesis of biarsenical probes that inhibit protein tyrosine phosphatases.