6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE
- Product Name
- 6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE
- CAS No.
- 20035-41-0
- Chemical Name
- 6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE
- Synonyms
- NSC95682;6-Bromo-2-hydroxy-2-methoxybenzaldehyde;6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE;2-Hydroxy-3-methoxy-6-bromobenzaldehyde;Benzaldehyde, 6-bromo-2-hydroxy-3-methoxy-;6-Bromo-2-hydroxy-3-methoxybenzaldehyde >6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE 99+%;6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE (NSC95682);6-Bromo-2-hydroxy-3-methoxybenzaldehyde, 10 mM in DMSO;IRE1,6 Bromo 2 hydroxy 3 methoxybenzaldehyde,6Bromo2hydroxy3methoxybenzaldehyde,inhibit,Inhibitor,NSC-95682,Inositol requiring enzyme 1,NSC 95682
- CBNumber
- CB5362165
- Molecular Formula
- C8H7BrO3
- Formula Weight
- 231.04
- MOL File
- 20035-41-0.mol
6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE Property
- Melting point:
- 102-105 °C(lit.)
- Boiling point:
- 282.1±35.0 °C(Predicted)
- Density
- 1.653±0.06 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Sealed in dry,Room Temperature
- solubility
- DMSO : 113 mg/mL (489.09 mM)
- form
- powder to crystal
- pka
- 7.21±0.15(Predicted)
- color
- Light yellow to Yellow to Orange
- InChI
- InChI=1S/C8H7BrO3/c1-12-7-3-2-6(9)5(4-10)8(7)11/h2-4,11H,1H3
- InChIKey
- JUPJZUTYDWXZAQ-UHFFFAOYSA-N
- SMILES
- C(=O)C1=C(Br)C=CC(OC)=C1O
- CAS DataBase Reference
- 20035-41-0(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 553581
- Product name
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 5g
- Price
- $127
- Updated
- 2023/06/20
- Product number
- 553581
- Product name
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
- Purity
- 98%
- Packaging
- 25g
- Price
- $364
- Updated
- 2023/01/07
- Product number
- B1487
- Product name
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
- Purity
- >99.0%(GC)(T)
- Packaging
- 1g
- Price
- $29
- Updated
- 2025/07/31
- Product number
- B1487
- Product name
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
- Purity
- >99.0%(GC)(T)
- Packaging
- 5g
- Price
- $86
- Updated
- 2025/07/31
- Product number
- B1487
- Product name
- 6-Bromo-2-hydroxy-3-methoxybenzaldehyde
- Purity
- >99.0%(GC)(T)
- Packaging
- 25g
- Price
- $253
- Updated
- 2025/07/31
6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE Chemical Properties,Usage,Production
Uses
6-Bromo-2-hydroxy-3-methoxybenzaldehyde may be used in the synthesis of:
- 2-benzyloxy-6-bromo-3-methoxybenzaldehyde
- biphenyls
- antihypertensive natural products S-(+)-XJP and R-(-)-XJP
General Description
6-Bromo-2-hydroxy-3-methoxybenzaldehyde is a bromobenzaldehyde derivative. It participates in the synthesis of (±)-norannuradhapurine. Its crystals exhibit monoclinic crystal system and space group P21/n.
Synthesis
159263-87-3
20035-41-0
2-Acetoxy-3-methoxy-6-bromobenzaldehyde (48.2 g, 176.5 mmol) was used as starting material and dissolved in methanol (500 mL). Subsequently, 6 N hydrochloric acid (500 mL) was slowly added and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the product was separated by diafiltration. The filter cake was washed with petroleum ether (100 mL × 3) and subsequently dried under vacuum to afford the yellow solid product 6-bromo-2-hydroxy-3-methoxybenzaldehyde (40.4 g, 99% yield).
References
[1] Patent: CN108358761, 2018, A. Location in patent: Paragraph 0042; 0043; 0078; 0079; 0096; 0097; 0105; 0106
[2] Journal of Medicinal Chemistry, 2000, vol. 43, # 14, p. 2731 - 2737
[3] Patent: US2003/220304, 2003, A1
[4] Patent: US2006/293394, 2006, A1. Location in patent: Figure 12
[5] Tetrahedron Letters, 2003, vol. 44, # 27, p. 5129 - 5132
6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE manufacturers
- Product
- 6-BROMO-2-HYDROXY-3-METHOXYBENZALDEHYDE 20035-41-0
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 200kg
- Release date
- 2019-12-31