1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE

Product Name: 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
CAS No.: 145645-62-1
Chemical Name: 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
Synonyms: NO-711;NNC 711;NNC711,HCl;NO-711 HYDROCHLORIDE;NNC-711 hydrochloride;YZYRTEYMUTWJPL-UHFFFAOYSA-N;NO-711 HCL POTENT GABA UPTAKE IN;1,2,5,6-Tetrahydro-1-(2-(((diphenylmethylene)amino)oxy]ethyl)-3-pyridinecarboxylicacidhydrochloride;1-[2-[[(diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride;1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE
CBNumber: CB5362529
Molecular Formula: C21H23ClN2O3
Formula Weight: 386.87
MOL File: 145645-62-1.mol

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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Property

storage temp.: protect from light
solubility: H₂O: ≥10 mg/mL at 60 °C
form: solid
color: off-white

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N142
Product name: NO-711 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $163
Updated: 2024/03/01

Sigma-Aldrich

Product number: N142
Product name: NO-711 hydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $337.8
Updated: 2024/03/01

Cayman Chemical

Product number: 29687
Product name: NNC-711 (hydrochloride)
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 29687
Product name: NNC-711 (hydrochloride)
Packaging: 25mg
Price: $343
Updated: 2024/03/01

Cayman Chemical

Product number: 29687
Product name: NNC-711 (hydrochloride)
Packaging: 5mg
Price: $139
Updated: 2024/03/01

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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Chemical Properties,Usage,Production

Uses

NNC 711 is an anticonvulsant agent and a selective GABA uptake inhibitor (1,2).

Uses

NO-711 hydrochloride is suitable for use as γ-aminobutyric acid (GABA) transporter-1 (GAT-1) antagonists or GABA uptake inhibitor.

Biological Activity

Potent and selective inhibitor of GABA uptake by GAT-1 (IC 50 values are 0.04, 171, 1700 and 622 μ M for hGAT-1, rGAT-2, hGAT-3 and hBGT-1 respectively). Anticonvulsant following systemic administration in vivo .

Biochem/physiol Actions

NO-711 is a potent and selective GABA uptake inhibitor that crosses the blood-brain barrier.

storage

Desiccate at +4°C

1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE Suppliers

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145645-62-1, 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDERelated Search:

3-(DIETHYLAMINO)PROPIONIC ACID HYDROCHLORIDE Benzophenone oxime 3-[(2-HYDROXYETHYL)AMINO]PROPANOIC ACID GUVACINE HYDROCHLORIDE 1-METHYL-1,2,3,6-TETRAHYDROPYRIDINE 1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE 2-DIETHYLAMINOMETHYL-ACRYLIC ACID 1,2,3,6-TETRAHYDROPYRIDINE HYDROCHLORIDE ARECAIDINE HYDROCHLORIDE

NO-711 HYDROCHLORIDE

NNC 711

1,2,5,6-TETRAHYDRO-1-[2-[[(DIPHENYLMETHYLENE)AMINO]OXY]ETHYL]-3-PYRIDINECARBOXYLIC ACID HYDROCHLORIDE

1-(2-(((DIPHENYLMETHYLENE)IMINO)OXY)ETHYL)-1,2,5,6-TETRAHYDRO-3-PYRIDINE CARBOXYLIC ACID HYDROCHLORIDE

NO-711 HCL POTENT GABA UPTAKE IN

1,2,5,6-Tetrahydro-1-(2-(((diphenylmethylene)amino)oxy]ethyl)-3-pyridinecarboxylicacidhydrochloride

NNC711,HCl

1-[2-[[(diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride

1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1,2,5,6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride

NNC-711 hydrochloride

YZYRTEYMUTWJPL-UHFFFAOYSA-N

NO-711

3-Pyridinecarboxylic acid, 1-[2-[[(diphenylmethylene)amino]oxy]ethyl]-1,2,5,6-tetrahydro-, hydrochloride (1:1)

1-[2-[[(Diphenylmethylene)imino]oxy]ethyl]-1，2，5，6-tetrahydro-3-pyridinecarboxylic acid hydrochloride hydrochloride， NNC-711 hydrochloride

145645-62-1

C21H22N2O3HCl

BioChemical

Cell Signaling and Neuroscience

Cell Biology

Ion Channels

Ligand-Gated Ion Channels

GABA and Glycine Receptor Modulators

GABA/Glycine receptor