THIENYLDECYL ISOTHIOCYANATE
- Product Name
- THIENYLDECYL ISOTHIOCYANATE
- CAS No.
- 288323-41-1
- Chemical Name
- THIENYLDECYL ISOTHIOCYANATE
- Synonyms
- THIENYLDECYL ISOTHIOCYANATE;Thiophene, 2-(10-isothiocyanatodecyl)-
- CBNumber
- CB5362998
- Molecular Formula
- C15H23NS2
- Formula Weight
- 281.48
- MOL File
- Mol file
THIENYLDECYL ISOTHIOCYANATE Property
- Boiling point:
- 399.5±15.0 °C(Predicted)
- Density
- 1.02±0.1 g/cm3(Predicted)
- storage temp.
- Store at -20°C
- solubility
- ≤30mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
- form
- solution in ethanol.
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H225Highly Flammable liquid and vapour
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233Keep container tightly closed.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242Use only non-sparking tools.
P243Take precautionary measures against static discharge.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
P403+P235Store in a well-ventilated place. Keep cool.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- 19653
- Product name
- Thienyldecyl Isothiocyanate
- Purity
- ≥98%
- Packaging
- 5mg
- Price
- $76
- Updated
- 2024/03/01
- Product number
- 19653
- Product name
- Thienyldecyl isothiocyanate
- Purity
- ≥98%
- Packaging
- 25 mg
- Price
- $302
- Updated
- 2024/03/01
- Product number
- 19653
- Product name
- Thienyldecyl Isothiocyanate
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $28
- Updated
- 2023/01/06
- Product number
- 19653
- Product name
- Thienyldecyl Isothiocyanate
- Purity
- ≥98%
- Packaging
- 10mg
- Price
- $136
- Updated
- 2024/03/01
- Product number
- C5554
- Product name
- ThienyldecylIsothiocyanate
- Packaging
- 5mg(solution)
- Price
- $158
- Updated
- 2021/12/16
THIENYLDECYL ISOTHIOCYANATE Chemical Properties,Usage,Production
Biological Activity
thienyldecyl isothiocyanate is a cytochrome p450 inhibitor [1].the human cytochrome p450 (cyp), a cellular chromophore, has been implicated in metabolism of drugs, arachidonic acid, foreign chemicals, and eicosanoids; steroid synthesis and metabolism; vitamin d3 synthesis and metabolism; cholesterol metabolism and bile-acid biosynthesis; retinoic acid hydroxylation. until now, there are more than 270 different cyp gene families have been identified, with 18 recorded in mammals. it has been repoted that cytochrome p450 is now understood to include a myriad of enzymic reactions implicated in important life processes. mutations in many cyp genes result in inborn errors of metabolism and contribute to many clinically relevant diseases [2].thienyldecyl isothiocyanate was an analog of thienylbutyl isothiocyanate. thienyldecyl isothiocyanate showed antiproliferative activity against cancer cells presumably that, like many isothiocyanates. thienyldecyl isothiocyanate functioned by modulation of xenobiotic-metabolizing enzymes, such as by inhibition of cytochrome p450, and/or by induction of phase ii detoxifying enzymes [1].
References
[1] yu r, mandlekar s, harvey k j, et al. chemopreventive isothiocyanates induce apoptosis and caspase-3-like protease activity[j]. cancer research, 1998, 58(3): 402-408.
[2] nebert d w, russell d w. clinical importance of the cytochromes p450[j]. the lancet, 2002, 360(9340): 1155-1162.
THIENYLDECYL ISOTHIOCYANATE Preparation Products And Raw materials
Raw materials
Preparation Products
THIENYLDECYL ISOTHIOCYANATE Suppliers
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