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4-CHLORO-3-METHYLBENZALDEHYDE

Product Name
4-CHLORO-3-METHYLBENZALDEHYDE
CAS No.
101349-71-7
Chemical Name
4-CHLORO-3-METHYLBENZALDEHYDE
Synonyms
4-CHLORO-3-METHYLBENZALDEHYDE;Benzaldehyde, 4-chloro-3-Methyl-;a-Chloro-3,5-difluoroacetophenone
CBNumber
CB5380480
Molecular Formula
C8H7ClO
Formula Weight
154.59
MOL File
101349-71-7.mol
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4-CHLORO-3-METHYLBENZALDEHYDE Property

Melting point:
27-28°C
Boiling point:
115°C 27mm
Density 
1.195±0.06 g/cm3(Predicted)
storage temp. 
under inert gas (nitrogen or Argon) at 2-8°C
Appearance
White to light yellow Solid
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38-51-41-37/38
Safety Statements 
26-36/37/39-39
HS Code 
2913000090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC
Product number
C367795
Product name
4-Chloro-3-methylbenzaldehyde
Packaging
1g
Price
$85
Updated
2021/12/16
TRC
Product number
C367795
Product name
4-Chloro-3-methylbenzaldehyde
Packaging
10g
Price
$525
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC149317
Product name
4-Chloro-3-methylbenzaldehyde
Packaging
5G
Price
$505
Updated
2021/12/16
Oakwood
Product number
022358
Product name
4-Chloro-3-methylbenzaldehyde
Purity
97%
Packaging
25g
Price
$510
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC149317
Product name
4-Chloro-3-methylbenzaldehyde
Packaging
1g
Price
$145
Updated
2021/12/16
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4-CHLORO-3-METHYLBENZALDEHYDE Chemical Properties,Usage,Production

Uses

4-Chloro-3-methylbenzaldehyde is a reactant used in the preparation of pyrrolidine Ureas as C-C chemokine receptor 1 (CCR1) antagonists.

Synthesis

4403-61-6

101349-71-7

1) Synthesis of intermediate A33-2: Phosphorus oxychloride (POCl3, 18.3 mL, 200 mmol) was added to a 100 mL two-necked flask and stirred 100 times. 2-Methyl-2-butenenitrile (A33-1, 10.43 g, 70%, 90 mmol) was dissolved in N,N-dimethylformamide (DMF, 15.4 mL, 200 mmol) and slowly added dropwise to the above solution. After the dropwise addition, the reaction was stirred at 110°C for 24 hours. After the reaction was completed, it was cooled to room temperature and the reaction mixture was slowly diluted with dichloromethane (100 mL) and then poured into ice water. The aqueous phase was extracted with dichloromethane (100 mL x 3), the organic phases were combined and washed with water. The organic phase was then washed with saturated saline (200 mL x 3), dried over anhydrous sodium sulfate, filtered to remove the desiccant, and the solvent was removed by rotary evaporation. The residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate=10:1) to give a white solid product (2.9 g, 21% yield).

References

[1] Patent: CN105254613, 2016, A. Location in patent: Paragraph 0246; 0247; 0248

4-CHLORO-3-METHYLBENZALDEHYDE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-CHLORO-3-METHYLBENZALDEHYDE Suppliers

China 79 Germany 2 India 3 United Kingdom 3 United States 13 Global 100
NovoChemy Ltd.
Tel
021-31261262/ 49 (0)17662837245
Fax
(0)21-33250524
Email
sales@novochemy.com
Country
Germany
ProdList
6328
Advantage
58
ABCR GmbH & CO. KG
Tel
--
Fax
--
Email
info@abcr.de
Country
Germany
ProdList
6831
Advantage
75
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View Lastest Price from 4-CHLORO-3-METHYLBENZALDEHYDE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD
Product
4-Chloro-3-methylbenzaldehyde 101349-71-7
Price
US $1.60-6.60/kg
Min. Order
1kg
Purity
99%
Supply Ability
100kg
Release date
2025-06-19
Shaanxi Dideu Medichem Co. Ltd
Product
4-Chloro-3-methylbenzaldehyde 101349-71-7
Price
US $0.00-0.00/KG
Min. Order
10mg
Purity
99%HPLC
Supply Ability
2000tons
Release date
2020-01-15
Career Henan Chemical Co
Product
4-CHLORO-3-METHYLBENZALDEHYDE 101349-71-7
Price
US $1.00/kg
Min. Order
1kg
Purity
95%-99%
Supply Ability
1000kg
Release date
2018-12-25

101349-71-7, 4-CHLORO-3-METHYLBENZALDEHYDERelated Search:

4-CHLORO-3-METHYLPHENYL METHANESULFONATE Methyl 4-chloro-3-Methylpicolinate 4-Chloro-3-methylbenzoic acid 4-Chloro-3-(trifluoromethyl)benzaldehyde 4-CHLORO-3-METHYLACETOPHENONE METHYL 4-CHLORO-3-METHYLBENZOATE 2-BROMO-1-(4-CHLORO-3-METHYLPHENYL)ETHAN-1-ONE 2-CHLORO-4-METHYLBENZALDEHYDE 2-CHLORO-6-METHYLBENZALDEHYDE 2,6-DICHLORO-4-METHYLBENZALDEHYDE 4-CHLORO-2-METHYLBENZALDEHYDE 3-CHLORO-4-METHYLBENZALDEHYDE, 97% MIN.,3-CHLORO-4-METHYLBENZALDEHYDE 97 m-Tolualdehyde TOLUALDEHYDES 3-(4-BROMO-2-THIENYL)-1-(4-CHLORO-3-METHYLPHENYL)PROP-2-EN-1-ONE 2-CHLOROANTHRAQUINONE-3-CARBOXYLIC ACID 1-(4-CHLORO-3-METHYLPHENYL)-3-(2,6-DICHLOROPHENYL)PROP-2-EN-1-ONE 6-CHLORO-7-METHYL ISATIN

  • 4-CHLORO-3-METHYLBENZALDEHYDE
  • Benzaldehyde, 4-chloro-3-Methyl-
  • a-Chloro-3,5-difluoroacetophenone
  • 101349-71-7