ChemicalBook > CAS DataBase List > CELECOXIB-D7

CELECOXIB-D7

Product Name
CELECOXIB-D7
CAS No.
544686-21-7
Chemical Name
CELECOXIB-D7
Synonyms
CELECOXIB-D7;Celecoxiβ-d7;[2H7]-Celecoxib;4-[5-[2,3,5,6-tetradeuterio-4-(trideuteriomethyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide;Celecoxib D7Q: What is Celecoxib D7 Q: What is the CAS Number of Celecoxib D7 Q: What is the storage condition of Celecoxib D7 Q: What are the applications of Celecoxib D7
CBNumber
CB5388385
Molecular Formula
C17H7D7F3N3O2S
Formula Weight
388.42
MOL File
Mol file
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CELECOXIB-D7 Property

storage temp. 
Store at -20°C
solubility 
DMSO: 76 mg/ml,Ethanol: 33 mg/ml
form 
A solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H360May damage fertility or the unborn child

H400Very toxic to aquatic life

H410Very toxic to aquatic life with long lasting effects

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P391Collect spillage. Hazardous to the aquatic environment

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
18248
Product name
Celecoxib-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
500μg
Price
$106
Updated
2024/03/01
Cayman Chemical
Product number
18248
Product name
Celecoxib-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
1mg
Price
$198
Updated
2024/03/01
Cayman Chemical
Product number
18248
Product name
Celecoxib-d7
Purity
≥99% deuterated forms (d1-d7)
Packaging
5mg
Price
$826
Updated
2024/03/01
TRC
Product number
C251004
Product name
Celecoxib-d7
Packaging
1mg
Price
$230
Updated
2021/12/16
Medical Isotopes, Inc.
Product number
D32648
Product name
Celecoxib-d7(tolyl-d7)
Packaging
0.01g
Price
$895
Updated
2021/12/16
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CELECOXIB-D7 Chemical Properties,Usage,Production

Description

Celecoxib-d7 is intended for use as an internal standard for the quantification of celecoxib by GC- or LC-MS. Celecoxib is a selective inhibitor of COX-2 (IC50s = 22.9 and 0.05 μM for COX-1 and COX-2, respectively). It displays chemopreventive activity in multiple tumor types via proapoptotic effects that are independent of COX-2 inhibition. Formulations containing celecoxib have been used in the treatment of inflammation while circumventing the gastrointestinal toxicity associated with traditional non-sterodial anti-inflammatory drugs, however, the use of celecoxib has been tempered due to its ability to induce adverse cardiovascular events.

Uses

Celecoxib-d7 is the labeled analogue of Celecoxib (C251000), a selective cyclooxygenase-2 (COX-2) inhibitor. Anti-inflammatory. Used in treatment of familial adenomatous polyposis.

CELECOXIB-D7 Preparation Products And Raw materials

Raw materials

Preparation Products

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544686-21-7, CELECOXIB-D7Related Search:

Celecoxib 2-Methyl Analog 4-DesMethyl-3-Methyl Celecoxib N-De(4-sulfonaMidophenyl)-N'-(4-sulfonaMidophenyl) Celecoxib Celecoxib

  • CELECOXIB-D7
  • 4-[5-[2,3,5,6-tetradeuterio-4-(trideuteriomethyl)phenyl]-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide
  • [2H7]-Celecoxib
  • Celecoxib D7Q: What is Celecoxib D7 Q: What is the CAS Number of Celecoxib D7 Q: What is the storage condition of Celecoxib D7 Q: What are the applications of Celecoxib D7
  • Celecoxiβ-d7
  • 544686-21-7
  • C17H7D7F3N3O2S