H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2
- Product Name
- H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2
- CAS No.
- 119386-39-9
- Chemical Name
- H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2
- Synonyms
- KKRAARATS-NH2;MYOSIN KINASE INHIBITING PEPTIDE;MYOSIN LIGHT CHAIN KINASE (11-19) AMIDE;LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2;H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2;LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-AMIDE;myosin light chain kinase fragment 11-19 amide;Myosin Light Chain Kinase Fragment 11-19 amide >=97% (HPLC);L-Serinamide, L-lysyl-L-lysyl-L-arginyl-L-alanyl-L-alanyl-L-arginyl-L-alanyl-L-threonyl-
- CBNumber
- CB5389559
- Molecular Formula
- C40H78N18O11
- Formula Weight
- 987.16
- MOL File
- 119386-39-9.mol
H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2 Property
- storage temp.
- −20°C
Safety
- WGK Germany
- 3
N-Bromosuccinimide Price
- Product number
- L2275
- Product name
- Myosin Light Chain Kinase Fragment 11-19 amide
- Purity
- ≥97% (HPLC)
- Packaging
- 5mg
- Price
- $451
- Updated
- 2023/01/07
- Product number
- M9848-02
- Product name
- Myosin Kinase Inhibiting Peptide
- Packaging
- 1mg
- Price
- $531
- Updated
- 2021/12/16
- Product number
- orb372574
- Product name
- Myosin Kinase Inhibiting Peptide
- Purity
- > 95%
- Packaging
- 5mg
- Price
- $688.5
- Updated
- 2021/12/16
- Product number
- orb372574
- Product name
- Myosin Kinase Inhibiting Peptide
- Purity
- > 95%
- Packaging
- 10mg
- Price
- $884
- Updated
- 2021/12/16
- Product number
- PEP0002560
- Product name
- MYOSIN LIGHT CHAIN KINASE (11-19) AMIDE
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $899.51
- Updated
- 2021/12/16
H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2 Chemical Properties,Usage,Production
Uses
Myosin light chain kinase fragment 11-19 amide (MLCK(11-19) amide) is a substrate-specific peptide inhibitor of MLCK. Myosin light chain kinase fragment 11-19 amide inhibits hypotonicity-induced Ca2+ entry. Myosin light chain kinase fragment 11-19 amide can be used in the research of human cervical cancer[1][2].
References
[1] Aromolaran AS, et al. Evidence for myosin light chain kinase mediating noradrenaline-evoked cation current in rabbit portal vein myocytes. J Physiol. 2000 May 1;524 Pt 3(Pt 3):853-63. DOI:10.1111/j.1469-7793.2000.00853.x
[2] Shen MR, et al. Myosin light chain kinase modulates hypotonicity-induced Ca2+ entry and Cl- channel activity in human cervical cancer cells. Pflugers Arch. 2002 May;444(1-2):276-85. DOI:10.1007/s00424-002-0811-3
[3] Chilcoat CD, et al. Tonic protein kinase A activity maintains inactive beta2 integrins in unstimulated neutrophils by reducing myosin light-chain phosphorylation: role of myosin light-chain kinase and Rho kinase. J Leukoc Biol. 2008 Apr;83(4):964-71. DOI:10.1189/jlb.0405192
H-LYS-LYS-ARG-ALA-ALA-ARG-ALA-THR-SER-NH2 Preparation Products And Raw materials
Raw materials
Preparation Products
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