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Chlorotripyrrolidinophosphonium hexafluorophosphate

Product Name
Chlorotripyrrolidinophosphonium hexafluorophosphate
CAS No.
133894-48-1
Chemical Name
Chlorotripyrrolidinophosphonium hexafluorophosphate
Synonyms
PYCLOP;PYCIOP;REF DUPL: PyClOP;Chlorotripyrrolidino;Chlorotripyrrolidinop;Chlorotripyrrolidinophosphonium;Chlorotriphenylalkyl hexafluorophosphate;Chlorotripyrrolidinophosphoniumhexafluorophosphat;CHLOROTRIPYRROLIDINOPHOSPHONIUM HEXAFLUOROPHOSPHATE;Chlorotriphyrrolidinyl hexafluorophosphate (PYCLOP)
CBNumber
CB5408289
Molecular Formula
C12H24ClF6N3P2
Formula Weight
421.73
MOL File
133894-48-1.mol
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Chlorotripyrrolidinophosphonium hexafluorophosphate Property

Melting point:
145-148°C
storage temp. 
2-8°C
solubility 
soluble in Chloroform, Methanol
form 
Crystalline Powder
color 
White to yellow
Sensitive 
Moisture Sensitive
BRN 
6842341
InChI
InChI=1S/C12H24ClN3P.F6P/c13-17(14-7-1-2-8-14,15-9-3-4-10-15)16-11-5-6-12-16;1-7(2,3,4,5)6/h1-12H2;/q+1;-1
InChIKey
BSCYRXJVGSZNKX-UHFFFAOYSA-N
SMILES
[P+5]([F-])([F-])([F-])([F-])([F-])[F-].[P+](N1CCCC1)(N1CCCC1)(N1CCCC1)Cl
CAS DataBase Reference
133894-48-1(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi,C
Risk Statements 
36/37/38-34
Safety Statements 
26-36-45-36/37/39
RIDADR 
UN 1759 8/PG 2
WGK Germany 
3
10-21
HazardClass 
8
PackingGroup 
II
HS Code 
29339900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H318Causes serious eye damage

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P330+P331IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
26564
Product name
Chlorotripyrrolidinophosphonium hexafluorophosphate
Purity
≥98.0% (AT)
Packaging
25g
Price
$353
Updated
2025/07/31
Sigma-Aldrich
Product number
26564
Product name
Chlorotripyrrolidinophosphonium hexafluorophosphate
Purity
≥98.0% (AT)
Packaging
5G
Price
$118
Updated
2023/06/20
TCI Chemical
Product number
C2551
Product name
Chlorotripyrrolidinophosphonium Hexafluorophosphate
Purity
>98.0%(HPLC)(T)
Packaging
5g
Price
$71
Updated
2025/07/31
TCI Chemical
Product number
C2551
Product name
Chlorotripyrrolidinophosphonium Hexafluorophosphate
Purity
>98.0%(HPLC)(T)
Packaging
25g
Price
$311
Updated
2023/06/20
Usbiological
Product number
286595
Product name
PyCloP
Packaging
1g
Price
$315
Updated
2021/12/16
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Chlorotripyrrolidinophosphonium hexafluorophosphate Chemical Properties,Usage,Production

Uses

Crystalline reagent for peptide coupling of a-alkylated N-Fmoc and N-Z-amino acids in high yield and without racemization.

Uses

Reagent for:
Peptide coupling reactions and synthesis of coupling reagents
Sequence selective peptide recognition
Synthesis of condensing reagents
Synthesis of heterocyclic β-sheet ligands

Preparation

Preparation of chlorotripyrrolidinophosphonium hexafluorophosphate: addition of chlorine to a diethyl ether solution of tripyrrolidinophosphine, then addition of KPF6 in water. Addition of tripyrrolidinophosphine oxide to a DCM solution of phosphoryl trichloride, then addition of KPF6 in water.

reaction suitability

reaction type: Coupling Reactions

Chlorotripyrrolidinophosphonium hexafluorophosphate Preparation Products And Raw materials

Raw materials

Preparation Products

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Chlorotripyrrolidinophosphonium hexafluorophosphate Suppliers

Changzhow Moisten International Trading Co., Ltd.
Tel
13606112397
Email
tang13606112397@163.com
Country
China
ProdList
191
Advantage
58
Suzhou Highfine Biotech Co., Ltd
Tel
0512-69209928 18796809688
Fax
0512-68417696
Email
zhouyingxiang@highfine.com
Country
China
ProdList
475
Advantage
75
Shanghai Yuben Technology Co., Ltd.
Tel
13917011423
Email
86908523@qq.com
Country
China
ProdList
58
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58
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
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76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
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62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
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57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44801
Advantage
61
Wuhan Chemwish Technology Co., Ltd
Tel
86-027-67849912
Fax
86-027-87531808
Email
sales@chemwish.com
Country
China
ProdList
35896
Advantage
56
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View Lastest Price from Chlorotripyrrolidinophosphonium hexafluorophosphate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
Chlorotripyrrolidinophosphonium hexafluorophosphate 133894-48-1
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
Chlorotripyrrolidinophosphonium hexafluorophosphate 133894-48-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
Chlorotripyrrolidinophosphonium hexafluorophosphate 133894-48-1
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

133894-48-1, Chlorotripyrrolidinophosphonium hexafluorophosphateRelated Search:


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