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GLY-ARG-GLY-ASP-SER

Product Name
GLY-ARG-GLY-ASP-SER
CAS No.
96426-21-0
Chemical Name
GLY-ARG-GLY-ASP-SER
Synonyms
GRGDS;GRGDS 1/2ACOH 2H2O;GLY-ARG-GLY-ASP-SER;H-GLY-ARG-GLY-ASP-SER-OH;Gly-Arg-Gly-Asp-Ser (TFA);GRGDS, fibrinogen fragment;GLY-ARG-GLY-ASP-SER ACETATE;GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O;Gly-Arg-Gly-Asp-Ser >=97% (HPLC);H-Gly-Arg-Gly-Asp-Ser-OH TFA salt
CBNumber
CB5414527
Molecular Formula
C17H30N8O9
Formula Weight
490.47
MOL File
96426-21-0.mol
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GLY-ARG-GLY-ASP-SER Property

Density 
1.66±0.1 g/cm3(Predicted)
storage temp. 
-20°C
solubility 
DMSO : 100 mg/mL (203.89 mM);Water : 33.33 mg/mL (67.96 mM)
form 
White to off-white lyophilized solid
pka
2.85±0.10(Predicted)
Sequence
H-Gly-Arg-Gly-Asp-Ser-OH
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
G4391
Product name
Gly-Arg-Gly-Asp-Ser
Purity
≥97% (HPLC)
Packaging
1mg
Price
$47.16
Updated
2024/03/01
Sigma-Aldrich
Product number
G4391
Product name
Gly-Arg-Gly-Asp-Ser
Purity
≥97% (HPLC)
Packaging
5mg
Price
$274
Updated
2024/03/01
ChemScene
Product number
CS-7044
Product name
Gly-Arg-Gly-Asp-Ser
Purity
95.05%
Packaging
5mg
Price
$108
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001478
Product name
GLY-ARG-GLY-ASP-SER
Purity
95.00%
Packaging
5MG
Price
$667.02
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0001478
Product name
GLY-ARG-GLY-ASP-SER
Purity
95.00%
Packaging
25MG
Price
$909.56
Updated
2021/12/16
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GLY-ARG-GLY-ASP-SER Chemical Properties,Usage,Production

Uses

Gly-Arg-Gly-Asp-Ser has been used-

  • as an antigen to determine whether integrin α4 or α5 hinders the adhesion of day 3 postirradiation thymocytes to thymic epithelial cells, in mice
  • for the treatment of collagen IV-coated dishes to study the role of integrins α1, αv, β1, and β3 in Sca-1+ progenitor cell differentiation into SMCs (smooth muscle cells)
  • as a blocking peptide for the pre-incubation of Nisseria meningitides strains, to perform blocking experiments to study the interactions between these bacterial strains and fibronectin
  • for the pre-treatment of EL-4 cells infected by AdCMV-GFP (cytomegalovirus-green fluorescent protein), to study whether interaction with cellular integrins is essential for the transduction of adenovirus

General Description

Gly-Arg-Gly-Asp-Ser peptide sequence is identical to the cell-binding region of fibronectin protein. Arg-Gly-Asp (RGD) region is found in various proteins, and is crucial for facilitating cell-adhesive activity.

Biochem/physiol Actions

Antagonist of integrin function

GLY-ARG-GLY-ASP-SER Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from GLY-ARG-GLY-ASP-SER manufacturers

Career Henan Chemical Co
Product
GLY-ARG-GLY-ASP-SER 96426-21-0
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

96426-21-0, GLY-ARG-GLY-ASP-SERRelated Search:


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  • GRGDS, FIBRONECTIN ATTACHMENT PEPTIDE
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  • GLY-ARG-GLY-ASP-SER 1/2ACOH 2H2O
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  • Glycyl-L-Arginylglycyl-L-alpha-Aspartyl-L-Serine
  • GRGDS, fibrinogen fragment
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  • Gly-Arg-Gly-Asp-Ser (TFA)
  • L-Serine, glycyl-L-arginylglycyl-L-α-aspartyl-
  • Gly-Arg-Gly-Asp-Ser >=97% (HPLC)
  • H-Gly-Arg-Gly-Asp-Ser-OH TFA salt
  • Glycyl-L-arginylglycyl-L-α-aspartyl-L-serine
  • 96426-21-0
  • Extracellular Matrix Peptides and Proteins
  • Extracellular Matrix
  • Cytoskeleton and Extracellular Matrix
  • Cell Biology
  • Cell Signaling and Neuroscience
  • BioChemical
  • Cell Signaling Enzymes
  • ECM Related Proteins and PeptidesCytoskeleton and Extracellular Matrix
  • Extracellular Matrix
  • Extracellular Matrix Peptides (ECM)
  • Extracellular Matrix Peptides and ProteinsPeptides for Cell Biology
  • Fibronectin Fragments and Analogs
  • Matrix Metalloproteinases Products
  • peptide