3'-DT CEP

Product Name: 3'-DT CEP
CAS No.: 142103-12-6
Chemical Name: 3'-DT CEP
Synonyms: 3'-dT;3'-DT CEP;5-METHYL-3'-DU CEP;3′-dT-CE Phosphoramidite;5-Me-3’-dU-2’-phosphoramidite;5-Me-3'-dU-2'-phosphoramidite;3'-Deoxy-5'-O-DMT-5-methyluridine2'-CEphosphoramidite;3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite;5’-O-DMTr-3’-deoxy-5-methyl?uridine-2’-CED-phosphoramidite;3′-Deoxy-5′-O-DMT-5-methyluridine 2′-CE phosphoramidite, CAS 142103-12-6
CBNumber: CB5414956
Molecular Formula: C40H49N4O8P
Formula Weight: 744.81
MOL File: 142103-12-6.mol

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3'-DT CEP Property

solubility: DMSO: Sparingly soluble: 1-10 mg/ml
Ethanol: Sparingly soluble: 1-10 mg/ml
pka: 9.55±0.10(Predicted)

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

American Custom Chemicals Corporation

Product number: NUC0002156
Product name: 3'-DEOXYTHYMIDINE 3'-CE PHOSPHORAMIDITE
Purity: 95.00%
Packaging: 5MG
Price: $495.36
Updated: 2021/12/16

Biosynth Carbosynth

Product number: PD08648
Product name: 3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite
Packaging: 250mg
Price: $1207.5
Updated: 2021/12/16

AK Scientific

Product number: 1129CW
Product name: 3-[[(2R,3R,5S)-5-[[Bis(4-methoxyphenyl)-phenylmethoxy]methyl]-2-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile
Packaging: 250mg
Price: $1680
Updated: 2021/12/16

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3'-DT CEP Chemical Properties,Usage,Production

Uses

5-Me-3’-dU-2’-phosphoramidite is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005
[2] TAKASHI OSAWA. Synthesis and hybridizing properties of isoDNAs including 3′-O,4′-C-ethyleneoxy-bridged 5-methyluridine derivatives[J]. Bioorganic & Medicinal Chemistry, 2018, 26 14: Pages 3875-3881. DOI: 10.1016/j.bmc.2018.05.043
[3] CARMELO J. RIZZO Ronald B ∗ Joseph P Dougherty. 3′-Deoxy-2′-phosphoramidites of adenosine and 5-methyluridine used for the solid phase synthesis of unnatural 3′-deoxy-2′–5″-Oligonucleotides.[J]. Tetrahedron Letters, 1992, 33 29: Pages 4129-4132. DOI: 10.1016/s0040-4039(00)74670-3

3'-DT CEP Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-DT CEP Suppliers

China 20 United Kingdom 2 United States 5 Global 27

Zhengzhou Granlen Sciences, ltd.

Tel: 0371-85513397 +86-18610099868
Email: info@granlen.com
Country: China
ProdList: 1890
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BOC Sciences

Tel: 16314854226; +16314854226
Email: inquiry@bocsci.com
Country: United States
ProdList: 19654
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NewCan Biotech Limited

Tel: +86-0571-86912261 +8613735419629
Email: sales@newcanbio.com
Country: China
ProdList: 9985
Advantage: 58

Amel Pharmatech Corporation

Tel: 027-888-4366503
Fax: 888-502-1736
Email: sales@amelpharmatech.com
Country: China
ProdList: 5000
Advantage: 58

BOC Sciences

Tel: 16314854226
Fax: 1-631-614-7828
Email: inquiry@bocsci.com
Country: United States
ProdList: 9713
Advantage: 58

Henan Kehong Biological Technology Co. LTD

Tel: 0371-86658258 ；0371-55969461
Fax: QQ：3311217266
Email: info@kehobio.com
Country: China
ProdList: 2575
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Nanjing Shizhou Biology Technology Co.,Ltd

Tel: 18351873721
Email: helen.zhang@synzest.com
Country: China
ProdList: 8295
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TargetMol Chemicals Inc.

Tel: 4008200310
Email: marketing@tsbiochem.com
Country: China
ProdList: 24961
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Beijing Qinling Pharmaceutical Co., Ltd.

Tel: 010-61241352 18901327973
Email: 834537306@qq.com
Country: China
ProdList: 5860
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Xi'an Kezhan Biotechnology Co., Ltd.

Tel: 18729005399
Email: 78282739@qq.com
Country: China
ProdList: 2302
Advantage: 58

142103-12-6, 3'-DT CEPRelated Search:

3'-DEOXY-5'-O-(DIMETHOXYTRITYL)-5-METHYLURIDINE 3'-Deoxy-5'-O-trityl-D-uridine 3'-DT CEP

3'-Deoxy-5'-O-DMT-5-methyluridine 2'-CE phosphoramidite

5'-O-[Bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-5-methyluridine 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5-METHYL-3'-DU CEP

3'-DT CEP

5-Me-3'-dU-2'-phosphoramidite

Uridine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-deoxy-5-methyl-, 2'-[2-cyanoethyl N,N-bis(1-methylethyl)phosphoramidite]

5’-O-(4,4-Dimethoxytrityl)-3’-deoxy-5-methyl uridine-2’-CED-phosphoramidite

Diisopropyl-phosphoramidous acid (2R,3R,5S)-5-[bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-tetrahydro-furan-3-yl ester 2-cyano-ethyl ester

5’-O-DMTr-3’-deoxy-5-methyl?uridine-2’-CED-phosphoramidite

3'-dT

5-Me-3’-dU-2’-phosphoramidite

3'-Deoxy-5'-O-DMT-5-methyluridine2'-CEphosphoramidite

(2R,3R,5S)-5-((Bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-2-(5-methyl-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite

3′-Deoxy-5′-O-DMT-5-methyluridine 2′-CE phosphoramidite, CAS 142103-12-6

3′-dT-CE Phosphoramidite

142103-12-6